week 7+8 - cardiovascular substance exchange Flashcards

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1
Q

SUBSTANCE EXCHANGE

A

Blood flow through capillaries
- Capillaries branch to form an extensive capillary network throughout the tissues and are found near almost every cell in the body

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2
Q

VASOMOTION

A
  • Smooth muscles contract and relax in metarterioles and precapillary sphincters
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3
Q

SUBSTANCE EXCHANGE IN CAPILLARIES
diffusion

A

o Through fenestration
o O2, CO2, glucose, amino acids, hormones

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4
Q

SUBSTANCE EXCHANGE IN CAPILLARIES
transcytosis

A

o In blood
o Pinocytic vesicles
o Lipid molecules
o Endocytosis and exocytosis

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5
Q

SUBSTANCE EXCHANGE IN CAPILLARIES
bulk flow

A

o Pressure differences
o Large no. ions

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6
Q

what order are vessels connected in?

A

artery –> arteriole –> capillaries –> venule –> vein

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7
Q

what is your blood pressure

A
  • Highest pressure at systole in arteries
    o Ventricular contraction
  • Lowest pressure at diastole in arteries
    o Ventricular contraction
  • PULSE: expansion & relax elastic arteries after each systole
    o “same as heart beat”
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8
Q

PHYSIOLOGICAL FACTORS AFFECTING BLOOD PRESSURE:

A
  • Cardiac output
    o Heart rate
    o End systolic volume
    o Myocardial contractivity
  • Blood volume
    o Venous pressure
  • Vascular resistance
    o Size of lumen
    o Blood viscosity
    o Vessel length
    o Venous return
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9
Q

what causes changes in your blood pressure

A
  • Behaviour (diet, exercise)
    o Gas and nutrient exchange to metabolic tissues
  • Environment (thermoregulation
  • Emotions (fright)
  • Lesions in brain
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10
Q

blood pressure controlled by…

A

negative feedback systems

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11
Q

negative feedback systems

A
  • Cardiovascular centre (CV) in medulla oblongata (brain):
    o Heart rate and stroke volume
    (feedback on blood pressure)
  • Neural regulation
  • Hormone regulation
  • Autoregulation:
    o Local metabolic demands
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