week 7+8 - cardiovascular substance exchange Flashcards
SUBSTANCE EXCHANGE
Blood flow through capillaries
- Capillaries branch to form an extensive capillary network throughout the tissues and are found near almost every cell in the body
VASOMOTION
- Smooth muscles contract and relax in metarterioles and precapillary sphincters
SUBSTANCE EXCHANGE IN CAPILLARIES
diffusion
o Through fenestration
o O2, CO2, glucose, amino acids, hormones
SUBSTANCE EXCHANGE IN CAPILLARIES
transcytosis
o In blood
o Pinocytic vesicles
o Lipid molecules
o Endocytosis and exocytosis
SUBSTANCE EXCHANGE IN CAPILLARIES
bulk flow
o Pressure differences
o Large no. ions
what order are vessels connected in?
artery –> arteriole –> capillaries –> venule –> vein
what is your blood pressure
- Highest pressure at systole in arteries
o Ventricular contraction - Lowest pressure at diastole in arteries
o Ventricular contraction - PULSE: expansion & relax elastic arteries after each systole
o “same as heart beat”
PHYSIOLOGICAL FACTORS AFFECTING BLOOD PRESSURE:
- Cardiac output
o Heart rate
o End systolic volume
o Myocardial contractivity - Blood volume
o Venous pressure - Vascular resistance
o Size of lumen
o Blood viscosity
o Vessel length
o Venous return
what causes changes in your blood pressure
- Behaviour (diet, exercise)
o Gas and nutrient exchange to metabolic tissues - Environment (thermoregulation
- Emotions (fright)
- Lesions in brain
blood pressure controlled by…
negative feedback systems
negative feedback systems
- Cardiovascular centre (CV) in medulla oblongata (brain):
o Heart rate and stroke volume
(feedback on blood pressure) - Neural regulation
- Hormone regulation
- Autoregulation:
o Local metabolic demands