Week 7

Question 1

Cholesterol is not soluble in an aqueous medium. Therefore, cholesterol is esterified to make it ___ hydrophobic. Cholesterol esters are incorporated into protein/lipid composites called ___.

Answer 1

More hydrophobic - but this is less soluble

So it is incorporated into lipoproteins

Question 2

What are the different types of lipoproteins, in order of lowest to highest density?

Answer 2

Chylomicron, VLDL, LDL, HDL

Question 3

In hypercholesterolaemia, there is increased total ___ (free and esterified) in blood. In hypertriglyceridaemia, there is an increased level of ___ in blood.

Answer 3

Hypercholesterolaemia - increased total cholesterol

Hypertriglyceridaemia - increased triacylglycerols/triglycerides

Question 4

The first region of the heart to be infarcted due to ischaemia is the ___, and then spreads outwards.

Answer 4

Subendocardium