week 7 Flashcards

1
Q

Interpretation CTG

A

Registration of contractions, foetal heart rythm; decelerations, accelerations, variability, baseline heartrate (most important).

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2
Q

What are the signs of hypoxia?

A

Complicated variable decelerations with a average of > 60 sec. Also no accelerations and missing variability.

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3
Q

What four factors are important in the fysiology of the fetal heart rythm?

A

Baroreceptors, chemoreceptors, SA node and autonomic nervous system

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4
Q

Why do decelerations exsist?

A

Are a protection mechanism of the heart, by putting down the HF -> less oxygen needed. If the heart muscle relaxes, the coronary arteries will open up > more oxygen heart.

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5
Q

What are the 3 stages of oxygen shortage?

A
  1. Hypoxemia: days-weeks. The growth decreases, even as the movement.
  2. Hypoxia: hours. Less oxygen to perifere. Central organs get enough oxygen.
  3. Asphyxia: Also less oxygen to the central organs. Takes 18 minutes.
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6
Q

What are the 3 central organs?

A

Brain, adrenal glands and heart.

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7
Q

What is MOTHERS? and what is the most important factor?

A
Causes for less oxygen.
Meconium stained fluid
Oxytocin! most important
Temperature mother
Hyperstimulation
Epidural
Rate of progress in labour
Scar
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8
Q

What are the 3 steps you take when the spiral arteries remain closed?

A
  1. Stop oxytocin
  2. Give tocolyse: stops contractions
  3. Call OK
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9
Q

What is the ABCDE of hypoxia?

A
Starts with decelerations.
A. accelerations will disappear
B. Baseline increases
C. Compensated stress
D. Decompensation
E. End stage (myocard failure)
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10
Q

What are the three types of hypoxia?

A
  1. Gradually evolving: takes hours
  2. Subacute: More decelerations. No baseline. Takes 30-60 minutes. pH decreses 0.01 every 3-6 minutes.
  3. Acute: sudden decrease of fetal heart rate> 3 minutes. pH decreases every minute.
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11
Q

What are causes of acute asphyxia?

A

Schoulder dystocia, uterine rupture, cord prolaps, placental abruption.

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12
Q

What is perinatal asphyxia?

A

Failure of gas exchange and blood supply, leading to hypoxia. 80% survives, of the 80%, 25% has severe impairment.

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13
Q

What are the phases of asfyxia?

A
  1. Primary energy failure: Important organs don’t get blood > neural damage
  2. Latent phase: 6 hours, body tries to function again; also brings slechte stoffen.
  3. secondary energy failure: reperfussion, inflammation, accumulation of harmfull neurotransmitters, oxidative injury, apoptosis, edema.
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14
Q

What does cooling do in asphyxia?

A

You want to start whithin 6 hours. If you bring down the temperature > less free radicals, inflammatory cascade, reduction of NO synthesis, inhibition of apoptosis. You cool core temperature > whole body

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15
Q

What are the side effects of cooling?

A

Sinus bradycardia, thrombocytopenia, more use iontropic drugs, persistent pulmonary hypertension, risk of sepsis, subcutaneous necrosis, slower metabolism.

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16
Q

Inclusion criteria for cooling are:

A
  • Amennorhea 36 weeks
  • Start whithin 6 hours
  • Asphyxia
  • Encephalopahty
17
Q

What are the criteria for asphyxia?

A
  1. AS 5 minutes < 5
  2. Resucitation or ventilation > 10 min
  3. PH <7
  4. Lactate > 10
  5. BE < -16
18
Q

What are the encephalopathy criteria?

A
  1. Thompson score > 7
  2. Abnormal aEEG
  3. Convulsions
19
Q

What is the protocol for cooling?

A

Rectal temperature <33.5 for 72 hours. You give sedation. Than warm up 0.2 degrees/30 minutes. Afterwards 24 hours 36.5