Week 6 Part 3 Common Bioceramics Flashcards
Al2O3 Aluminum oxide properties (5)
- nearly inert
- excellent biocompatibility
- high density
- high wear resistance
- grain size < 4 micrometers
Al2O3 applications
polycrystalline powder used in pharmaceuticals, artificial joints, and dental applications
Al2O3 made by ____________
solid state sintering - particles joined together
ZrO2 Zirconia properties
- nearly inert
- exceptional mechanical strength
- biocompatibility
Zirconia is made by ________________
solid state sintering
Zirconium dioxide applications
- dental crowns
- bridges
- implants
Bioglass is also
calcium sodium phosphosilicate
Bio glass properties
- bioactive
- non-crystalline
Bio glass applications
- bond to tissue
- improve other ceramics performance
- bone grafts
- cranial & maxillofacial repair
- nerve repair
Calcium phosphate applications
- orthopedic
- bone grafts
- tissue engineering
Calcium phosphate at body temp. and pH < 4.2 =
dicalcium phosphate
Calcium phosphate at body temp. and pH > 4.2 =
Ha, tricalcium phosphate
Hydroxyapatite (HA) is a
naturally occurring mineral form of calcium apatite
HA applications
orthopedic and dental
1. bone grafts
2. coatings for dental implants
3. bone tissue engr scaffolds
HA property
low solubility
Biphasic calcium phosphate (BCP) used in
bone grafting because of similarity to mineral composition of bones
When designing medical devices with ceramics, consider the following:
- understand the application
- biocompatibility
- choose the right ceramic
- ceramic composites
ceramic composites
blending ceramics with other materials
Mechanical considerations of ceramics
brittle so the design must account for their mechanical properties and prevent fractures
- optimize shape, thickness, and stress distribution
Surface finish
roughness and finish are crucial for biocompatibility and wear resistance
Manufacturing processes
each method has advantages and disadvantages
quality control
to implement stringent QC measures to ensure the final product meets required standards
mechanical testing
conduct tests to assess the device’s strength, hardness, and wear resistance under realistic conditions
