Week 6 Part 2: Substance Abuse Flashcards
Addiction
condition of continued use of substances (or reward seeking behaviors) despite adverse consequences
Withdrawal
Painful physical and or psychological that follow that the discontinuance of the substance(s)
Substance Induced Disorder
occur when medications used for other medical/mental health disorders cause intoxication or withdrawal or other health problems
Substance Use Disorder
occurs when substance use continues despite cognitive ,behavior, and physiological symptoms
Addiction is behavior patterns with…
overwhelming compulsive involvement with securing and using a substance
What is there a high tendency for what following drug discontinuation with addiction
relapse
Addiction is a disease of ____
perception
___ is a major component of addiction
Denail
People with addictions refuse to…
admit powerlessness over the problems
People with addictions will continue…
to use despite the negative consequences
How do those with addictions justify their behavior
they justify behaviors and use with blame on external sources for addiction
How big is the incidence of drug abuse
10.6% of those over 12 yo use ilict drugs
millions addicted to prescription painkillers, cocaine, hallucinogens, marijuana. alcohol, bing drinking, heavy alcohol use
How many people have a substance use disorder in the US
20.1 million people
What sort of substance use misuse is more common in teens and young adults
drinking
What groups are more likely to abuse drinking
teens and young adults
college students in higher quantities, but lower frequency than non college students
men drink in more harmful ways than women
What ends up being very costly for the US economy regarding drugs
abuse of tobacco, alcohol, and ilicit drug abuse
tobacco - 300 billion; alcohol 249 billion; ilicit drugs 193 billion; opioids 78.5 billions
___% of those with a serious mental illness have a ___ ___ ___ some time in their lives
50%; substance use disorder
Psychiatric disorders associated with substance abuse
acute and chronic cognitive impairment disorders
ADD
BPD and Antisocial PD
Anxiety disorders
depression and higher risk for suicide
eating disorders
compulsive behavior
4 Important theories of addiction
biological
psychological
behavior
sociocultural
Biological Theory of Addiction
specific effects on selected NTs, NIH
specific genes increase risk for addiction
physiologic mechanisms for compulsion despite consequences –> dopamine adn pleasure
Psychological Theory of Addiction
Impulsive and Risk Taking Behavior!!!
Defense against anxious impulses
oral regression (dependency)
Self medication for depression, hallucinations, thought disorders, PTSD, stress response, coping styles
Behavioral Theory of Addiction
positive reinforcement effects of drug seeking behavior
Sociocultural Theory of Addiction
social and cultural norms
socioeconomic stress
Tolerance
the need for higher and hgiher doses to achieve the desired effect
Withdrawal
after a long period of continued use, stopping or reducing a drug results in specific physical and psychological s/s
How does tolerance and withdrawal differ
Tolerance is needing higher doses for getting an effect, withdrawal is the physical and psych symptoms from discontinued use or not getting enough
The healthy liver can metabolizehow much alcohol per hour
1 ounce of alcohol
What happens to the excess alcohol that the liver cannot metabolize in an hour ?
it remains in the blood –> raises BAC/BAL
What BAL (mg%) causes change in mood, behavior, and impaired judgment in a non tolerant drinker
0.05%
What BAL (mg%) causes staggering, ataxia, and labile emotions in a non tolerant drinker
0.20%
What BAL (mg%) causes coma in a non tolerant drinker
0.40%
What BAL (mg%) causes death from respiratory depression in a non tolerant drinker
0.50%
BAL can be used to assess what?
- Level of intoxication
2. Level of tolerance
As tolerance develops, what occurs with the BAL measurement
there is a greater discrepancy between BAL and exepcted behavior as tolerance increases
What systems can be damaged and have a comorbidity due to alcohol use
GI System
Cardiovascular System
Liver Damage
CNS
What GI system comorbidities can occur from alcohol abuse
esophagitis
gastritis
pancreatitis
gastric ulcers
related issues of increased acid production and poor nutrition and absorption
impaired peristalsis
What Cardiovascular system comorbidities can occur from alcohol abuse
HTN
Cardiomyopathy
Dysrhythmias
Malnutrition
What is the primary organ for ETOH metabolism
Liver
What sort of medical comorbidities can occur from alcohol abuse in the liver
Fatty Liver
Hepatitis
Cirrhosis
Clinical Signs of Alcohol Induced Liver Damage
reddened palms
contractures and or clubbing of fingers and nails
white nails
NV
enlarged or inflammed liver
elevated LFTs
Comorbidities that can occur in the CNS from alcohol abuse
Wernicke’s Encephalopathy
Korsakoff’s Amnestic Syndrome
Thyamine Deficiences
Alcohol Demetia
Blackouts
Intoxication
Wernicke’s Encephalopathy
Comorbidity caused by alcohol in the CNS
a degeneerative brain disorder, caused by Thiamine deficiency
Leads to inability to learn new information, recall remote information, unsteady gait, myopathy (muscle weakness and wasting, as well as pain and tenderness)