WEEK 6 Breast Disorders Flashcards
What are the 2 Healthy People 2020 Objectives for BREAST CANCER?
- ↓ female deaths from breast cancer
2. ↑ proportion women who receive a breast cancer screening based on most recent guidelines
What are the 2 Healthy People 2020 Objectives for PROSTATE CANCER?
- ↓ deaths from prostate cancer
- ↑ proportion of men who have discussed with their HCP whether or not to have a prostate-specific antigen (PSA) test to screen for prostate cancer
Fibroadenoma is a __ breast disorder
benign
In Fibroadenoma, there is a __, __ __ __ mass. This mass is: (6)
solid
slowly enlarging benign
round firm easily movable rubbery non-tender clearly delineated from surrounding tissue
Fibroadenoma is usually located in the __ __ __ of the breast
upper outer quadrant
When is Fibroadenoma most common?
It is most common during reproductive years
There is an immediate fear of an increased risk for breast cancer for these women who have Fibroadenoma. The chances of breast cancer are __ __
very small
what is a cyst?
a fluid filled mass
what does fibrosis mean?
the thickening and scarring of connective tissue, usually as a result of injury
In Fibrocystic Breast Condition, there are fibrocystic changes of the breast involving which 3 areas?
- lobules
- ducts
- stromal tissues
Fibrocystic Breast Condition is most common in…
premenopausal women between 20 and 50 years of age
Fibrocystic Breast Condition is possibly caused by the…
imbalance in normal estrogen-to-progesterone ratio
Does fibrocystic breast condition increase the risk of breast cancer?
NO
Describe the characteristics of fibrocystic breast condition. (7)
It contains:
What other symptoms are there?
- fibrosis and cysts
- rubbery, ill-defined
- painful/tender
- increased tenderness and size PRIOR to menstruation
- symptoms increase in the premenstrual phase
- also freely movable
- symptoms usually resolve during menstruation
What are the diagnostic studies for fibrocystic breast changes? (4)
- Aspiration biopsy
- Needle biopsy
- Mammography
- Ultrasound
If fibrocystic breast changes are very troublesome, __ __ is an option
surgical removal
Other collaborative care measures for patients with fibrocystic breast changes include __ __, __ __ __, and __.
supportive undergarments
OTC pain relievers
hormones
What specific hormones are prescribed for patients with fibrocystic breast changes?
oral contraceptives
How do oral contraceptives help patients with fibrocystic breast changes? What should you watch out for when giving oral contraceptives?
- oral contraceptives balance hormone levels and symptom management
- Watch out for DVTs for people greater than 35, PE, CVA
What is the point of doing an aspiration biopsy for a patient with fibrocystic breast changes?
To check and see if there are cancer cells in the fluid
Patients with fibrocystic breast changes should consume less __. Decreasing this ___ can lower symptoms like __.
caffeine
premenstrually
inflammation
Patients with fibrocystic breast changes should take __ and have a low __ diet or take __
vitamins
Na+
diuretics
Breast cancer is the __ leading cause of DEATH for women.
2nd
Deaths from breast cancer have __ since __.
decreased
1990
African American women have more __ breast cancer EVEN IF detected early
aggressive
What are complications of breast cancer? (4)
- Invasion of lymph channels causing skin edema
- Metastasis to lymph nodes
- Bone, lungs, brain, liver - sites of metastatic disease from breast cancer
- Ulceration of overlying skin
Breast cancer occurs __% in the upper outside quadrant,. This quadrant has the highest breast cancer occurrence b/c…
50%
that’s the location with the majority of glandular tissue
In breast cancer, the tumor is: (4)
- regularly shaped
- poorly delineated
- nonmovable
- nontender
What does noninvasive breast cancer mean? How many percent of breast cancers are noninvasive?
the cancer stays within the duct
20%
What does invasive breast cancer mean?
it penetrates surrounding tissue
Which of the following is a risk factor for developing breast cancer?
- Age greater than 35 years
- Early menopause less than age 45
- First birth less than age 20
- Early Menarche less than age 12
4 Early menarche b/c of prolonged exposure to estrogen
What are risk factors for breast cancer?
- Gender
- Age 55 years or older
- Inherited mutations BRCA 1 or 2
- Family hx
- Race and Ethnicity
- Dense Breast tissue
- Previous hx breast CA
- Early menarche (12 y/o)
- Late menopause (greater than 55 y/o)
- Previous chest radiation (esp. adolescence)
- Diethylstilbestrol (DES) exposure
An individual with inherited mutations BRCA 1 or 2 has an __ lifetime risk of breast cancer
80%
A person with a family history of breast cancer has a __-__% risk
20-30%
A person with a family history of breast cancer relating to a 1st degree relative:
- ) mother/sister/daughter - has a __X risk
- ) father/brother - what’s the risk?
- ) two 1st degree relative has a __X risk
- 2
- unknown
- 5
Breast Cancer Risk Factors: Race & Ethnicity:
White ->
Black ->
White: has a greater risk of developing breast ca
Black: has a greater risk of dying
What is DES? What does it stand for?
it’s a synthetic estrogen
Diethylstilbestrol
When were women given DES? Why were they given DES?
during the 1940s -1970s to reduce complications and complications
Do having kids or not having kids pose as a risk factor for breast cancer? why?
not having kids
you are not breastfeeding
Does having the first child after the age of 30 or before 30 pose as a risk factor for breast cancer?
AFTER age 30
__% of women who get breast cancer do not have a family history
85
Postmenopausal women who are on __ __ also have a risk for breast cancer
hormonal therapy
What type of modifiable risk factors are there for breast cancer? (4)
- excess alcohol intake
- lack of physical activity
- birth control
- being overweight or obese
__-___ lesions such as __ __ and __ lesions such as __ are also breast cancer risk factors
non-proliferative; ductal ectasia
proliferative; fibroadenoma
Why are being overweight/obese or lacking physical activity or being over age 55 risk factors of breast cancer?
Fat tissue holds estrogen especially when ovaries stop working
What are 4 factors with unclear effects on breast cancer risk?
- diet and vitamin intake - vitamin D and calcium
- chemicals in the environment
- tobacco smoke
- night work
What are 4 disproven or controversial breast cancer risk factors?
- Antiperspirants
- Bras
- Induced abortion
- Breast implants
BRCA1 and BRCA2 are __; it is their __ that is abnormal
normal
mutation
When an individual inherits a mutated copy of __ __ from a parent, the individual has a __ risk of breast cancer
either gene
high
BRCA1 mutations have a lifetime risk as high as __%. The average risk is __-__%
80%
55-65%
BRCA2 mutations have a lifetime risk around __%
45%
In the United States, BRCA mutations are more common in __ __ of __
Jewish people ; Ashkenazi
BRCA1 and BRCA2 gene mutations occur more so in __ __ origin than in other racial and ethnic groups, but they can occur in __
Eastern Europe
anyone
__ testing can be done to determine if an individual has a BRCA1 or BRCA2 mutation.
Genetic
Inheriting a mutated copy of a gene is more of a risk factor for __ women than __ women
younger; older