Week 6 Flashcards
What is primary prevention?
Treatment before the disease has occurred
What is secondary prevention?
Treatment when the disease is already present
What is the effect of statins?
Lower LDL -> lower CVD
What is the effect of PCSK9 inhibitors?
Lower LDL
What are antiplatelet drugs (aspirin) used for?
CVD risk reduction in secondary prevention
Arterial diseases
Platelets play a very small role in venous diseases
Would you use platelet inhibition drugs in primary prevention?
Maybe in young patients (mainly if they have diabetes), not in old patients because the risk of bleeding is too large.
Why does atherosclerosis mainly develop in arteries, and not in veins?
Because atherosclerosis mainly forms because of shear stress, because of high BP
What do diuretics do?
Decrease BP: remove salt and fluid
Beta-blockers
Decrease BP: decrease heart contractability
ACE inhibitors and angiotensin blockers
Decrease BP: works on renin
What antihypertensive drugs do you give to old or black people?
diuretics or calcium antagonists
What antihypertensive drugs do you give to young people?
ACE inhibitors or angiotensin receptor blockers, also work for kidney problems, MI, heart failure
What medication would you use for initial therapy of hypertension?
Dual therapy: ACE or ARB and calcium blocker or diuretic
What do you do when the initial therapy does not work?
Add another tablet
What do you do when 3 types of hypertensive medications still do not work?
Give spironolactone
