Week 5 - The Skeletal System Flashcards
Question
Answer
What composes the skeletal system?
All the bones and their associated cartilages, including bone (osseous) tissue, cartilage, dense connective tissue, epithelial tissue, adipose tissue, and nervous tissue.
Why is each individual bone considered an organ?
Because it comprises various tissues working together.
What are the six functions of the skeletal system?
Support, protection, assistance in movement, mineral homeostasis, blood cell production, triglyceride storage.
How does the skeletal system provide support?
It serves as the structural framework for the body, supporting soft tissues and providing attachment points for tendons.
How does the skeletal system protect the body?
It shields internal organs from injury, such as the skull protecting the brain and the rib cage protecting the heart and lungs.
How does the skeletal system assist in movement?
It provides anchor points for skeletal muscles, allowing for coordinated movements.
What is mineral homeostasis, and how does the skeletal system contribute to it?
It involves storing and releasing minerals, particularly calcium and phosphorus, to maintain proper levels in the blood.
What is hematopoiesis, and where does it occur?
Hematopoiesis is the production of blood cells, occurring in the red bone marrow.
What is stored in yellow bone marrow, and what is its function?
Yellow bone marrow stores triglycerides, serving as an energy reserve.
What is the diaphysis of a long bone?
The long, cylindrical shaft of the bone.
What are the epiphyses of a long bone?
The proximal and distal ends of the bone.
What are the metaphyses, and what do they contain in growing bones?
The regions between the diaphysis and epiphyses; they contain the epiphyseal (growth) plate in growing bones, which becomes the epiphyseal line in adults.
What is articular cartilage, and where is it found?
A thin layer of hyaline cartilage covering the epiphyses, reducing friction and absorbing shock at joints.
What is the periosteum, and what are its functions?
A tough connective tissue sheath covering the bone’s surface (except at joints), protecting the bone and serving as an attachment point for tendons and ligaments.
What is the medullary cavity, and what does it contain?
A hollow space within the diaphysis containing yellow bone marrow, which reduces the weight of the bone.
What is the endosteum?
A thin membrane lining the medullary cavity, containing bone-forming cells.
What is the composition of the bone’s extracellular matrix (ECM)?
15% water, 30% collagen fibers, 55% crystallized mineral salts.
What are osteoprogenitor (osteogenic) cells?
Unspecialized stem cells that divide to produce osteoblasts; found in the periosteum, endosteum, and canals containing blood vessels.
What are osteoblasts, and what is their function?
Immature bone cells responsible for bone formation, secreting collagen fibers and other organic components, and initiating calcification.
What are osteocytes, and where are they located?
Mature bone cells derived from osteoblasts, located within lacunae; they maintain bone tissue and regulate bone remodeling.
What are osteoclasts, and what is their role?
Large cells formed from the fusion of monocytes, responsible for bone resorption and regulating blood calcium levels; found in the endosteum.
What is calcification?
The process initiated by osteoblasts in which mineral salts and ions are deposited in a collagen framework, hardening the tissue to form bone.
What are the two types of bone tissue?
Compact (cortical) bone and spongy (trabecular or cancellous) bone.
What are the characteristics of compact bone?
Dense and strong, composed of osteons (Haversian systems), with central canals containing blood vessels and nerves, surrounded by concentric lamellae.
What are osteons, and what are their components?
Structural units of compact bone, consisting of osteonic (Haversian) canals, concentric lamellae, lacunae with osteocytes, and canaliculi for nutrient and waste exchange.
What are interstitial lamellae?
Fragments of older osteons that fill the spaces between osteons in compact bone.
What are circumferential lamellae?
Lamellae that encircle the bone just beneath the periosteum or around the medullary cavity, providing added strength.
What are the characteristics of spongy bone?
Composed of trabeculae, surrounded by red bone marrow, providing structural support, protecting red bone marrow, and reducing bone weight.
Where is spongy bone typically found?
In the epiphyses of long bones, the interior of short, flat, and irregular bones, and lining the medullary cavity of long bones.
What are the four zones of the epiphyseal growth plate?
Zone of resting cartilage, zone of proliferating cartilage, zone of hypertrophic cartilage, and zone of calcified cartilage.
What happens in the zone of resting cartilage?
Chondrocytes anchor the epiphyseal plate to the epiphysis, providing stability.
What occurs in the zone of proliferating cartilage?
Chondrocytes divide by mitosis, increasing the number of cells and contributing to bone growth in length.
What occurs in the zone of hypertrophic cartilage?
Chondrocytes mature and enlarge, preparing to calcify.
What happens in the zone of calcified cartilage?
Cartilage is calcified and replaced by bone tissue, contributing to the lengthening of the diaphysis.
What is the process of bone growth in thickness?
Appositional growth, where osteoblasts deposit new bone beneath the periosteum, increasing the diameter, and osteoclasts resorb bone on the endosteal surface, expanding the medullary cavity.
What is bone remodeling, and why is it important?
The ongoing replacement of old bone tissue with new bone tissue, maintaining bone strength and integrity, regulating calcium levels, and adapting to stress.