Week 5- Oral Complications Flashcards

1
Q

What are effects of tumour metabolites?

A
  • Facial flushing
  • Pigmentations
  • Amyloidosis
  • Oral erosions
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2
Q

What are some potential changes caused by functional disturbances if pt has cancer?

A
  • Purpura
  • Bleeding
  • Infections
  • Anaemia
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3
Q

What is radiotherapy?

A

Ionising radiation therapy used to control/kill malignant cells by damaging DNA

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4
Q

What are radiation effects to skin and mucosa?

A

Erythema

Ulceration

Mucositis

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5
Q

What are radiation effects to muscle and connective tissue?

A
  • Trismus
  • Limited access for self care and operative care
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6
Q

What are radiation effects to bone?

A

ORN

Obliterans

Endarteritis

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7
Q

What are oral complications of radiotherapy?

A
  • Mucositis
  • Ulceration
  • Candidosis
  • Xerostomia
  • Radiation caries
  • Loss of taste
  • Dental hypersensitivity
  • Perio
  • Trismus
  • ORN
  • Craniofacial defects
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8
Q

What is this?

A

Osteoradionecrosis

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9
Q

Why can’t bone heal following radiation therapy?

A

Radiation kills osteocytes

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10
Q

What are dental pre-radiotherapy considerations?

A
  • OH/Prevention/Restorative Care
  • Risk/benefit of retaining teeth
  • Dental exrtactions
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11
Q

How is radiation administered to help prevent permanently damaging healthy tissues?

A

Fractionations

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12
Q

What are dental considerations for during radiotherapy treatment?

A
  • Discourage Smoking & Alcohol
  • Eliminate Infections
  • Relieve Mucositis
  • Saliva Substitutes
  • Physiotherapy for Trismus
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12
Q

What are dental considerations for during radiotherapy treatment?

A
  • Discourage smoking and alcohol
  • Eliminate infections
  • Relieve mucositis
  • Saliva substitutes
  • Physiotherapy for trismus
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13
Q

What are dental considerations after radiotherapy?

A
  • Continue OH/preventative care
  • Antibiotics for infections
  • Specialist OMFS for exos/oral surgery
  • Topical fluoride
  • Avoid mucosal trauma
  • Saliva substitutes
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14
Q

What are characteristics of chemotherapy?

A
  • Cytotoxic anti-cancer drugs
  • Kill rapidly dividing cells
  • Single agent/combination
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15
Q

What are oral complications of chemotherapy?

A
  • Infections
  • Ulcers & mucositis
  • Lip cracking
  • Bleeding
  • Xerostomia
  • Perio disease
  • Delayed/abnormal development
16
Q

What is required before chemotherapy?

A
  • Oral and dental assessment
  • Oral hygiene
17
Q

What are considerations for during chemotherapy?

A
  • Folic acid to reduce ulcers
  • Ice cold water/sucking ice
  • Diluted CHX mouthwash
  • Nystatin for candidosis
  • Acyclovir for herpetic infection
  • Antibiotics for infections
  • Methotrexate interaction with NSAIDs/Aspirin
18
Q

What is methotrexate used to treat?

A

Rheumatoid arthritis

19
Q

What are considerations for after chemotherapy?

A
  • OH/Preventative dentistry
  • Risk of anaemia/bleeding/infection
20
Q

What is one of the main reasons pts stop chemotherapy and radiotherapy?

A

Oral mucositis

21
Q

What are characteristics of oral mucositis?

A
  • Widespread erythema
  • Ulceration
  • Soreness & bleeding
22
Q

What is this?

A

Oral Mucositis

23
Q

What is the WHO scale for mucositis?

A
  1. Soreness / Erythema
  2. Erythema & ulcers / Able to eat solids
  3. Ulcers / Requires liquid diet
  4. Oral intake not possible
24
Q

What is the management for oral mucositis?

A
  • PCA/Opioids
  • Avoid smoking, spirits, spices
  • Good OH
  • Oral cooling (crushed ice and water)
  • Topical anlagesics
  • Growth factor M/W
25
Q

What is this?

A

Oral Mucositis

26
Q

What are the short term effects of surgery?

A
  • Difficulty swallowing and speaking
  • Anaesthesia
  • Paraesthesia
27
Q

What are long terms effects of surgery?

A
  • Tissue and bone loss
  • Functional problems
  • Cosmetic concerns
  • Difficulty swallowing and speaking