Week 5 Heart Failure Flashcards
What is heart failure ?
Unable to pump blood from the ventricles to meet body’s metabolic needs
Left sided failure causes
Elevated left ventricular pressure cause pulmonary edema
Right sided failure causes
Peripheral edema (ankles,jugular venous distension)
What is inotropy ?
Force of myocardial contraction
What is Chronotropy ?
Heart rate
What is Dromotropy ?
Cardiac nerve conduction (electrolytes)
What is a cardiac glycosides ?
Digoxin
Early treatment for heart failure
Ace inhibitor, ARBS, Beta Blockers
What is used to reduce symptoms of heart failure
Loop diuretics
Aldosterone inhibitor
Spironolactone and eplerenone
Are added as heart failure progresses. Stops aldosterone cause kidneys to cause water and sodium and keep potassium
Recommend drugs for black patients
Hydrazine/isosorbide dinitrate
What do spirinolactone and eplerenone ?
Causes RAAS which causes retention of sodium and water which leads to edema that worsens heart failure
Phosphodietsterase inhibitors/ inodilators
Works by inhibiting the enzymes phosphodiesterase cause positive in tropic, vasodilation.
What is phosphodiesterase inhibitor
Milrinone (only iv)
Adverse effects:
Thrombocytopenia, cardiac dysrhythias
