Week 5 Flashcards
Lateralisation of the cerebral cortex
- The cortical regions are responsible for a particular psychological function are located in only one of the hemispheres OR
- Both hemispheres contribute, but the contribution of one is more important than or different to that of the other
Corpus callosum
- Bundle of fibres that crosses over between the two hemispheres
Divided visual field technique
- Relies on the visual anatomy of the pathway of the eye to the cerebral cortex
- Image showed briefly
- Sperry
Split brain study
- Presented in the right visual field – processed in the left hemisphere – verbal
- Presented in the left visual field – processed in the right hemisphere – visual
Block study
- Views a pattern made with squares and told to recreate using blocks
- Left hand – can complete it – right hemisphere
- Right hand – find it hard – left hemisphere
- Right hemisphere linked to visuospatial tasks
Lateralisation of language – Wada test
- Deactivate one hemisphere
- Person loses power of speech if left hemisphere is put to sleep
- However, can grab things with the left hand – right hemisphere
Language being across the brain
- In most people tested
- Fundamental components of language are located in the left hemisphere
- Can be in the right hemisphere – left handed
Broca
- Damage to Broca’s area
- Problems with language production – broca’s aphasia
- Doesn’t seem to effect comprehension
Broca’s area location
- An area in the left frontal lobe
- Next to the motor cortex
Broca’s aphasia symptoms
- Slow, laboured speech output
- Some degree of anomia
- Paraphasic errors
- Telegraphic speech
- Repetition of multisyllabic words impaired
- Aware of deficit and easily frustrated
Wernicke
- Can produce fluent, grammatical speech
- Difficulties comprehending spoken or written language
- Wernicke’s aphasia
Wernicke’s aphasia symptoms
- Problems understanding spoken and written language
- Speech is fluent with normal grammar
- Phonemic and semantic paraphasia – substituting words that related to eachother
Wernicke’s area
- Damage located in the posterior part of the superior temporal gyrus
Wernicke-Geschwind model
- Model of language organisation in the brain
- It shows how different region with different functions interact in language production and comprehension
Wernicke-Geschwind Broca’s area
- Formulates the speech plan implemented by motor cortex
- Turns intended meanings into motor plans for the speech articulators
Wernicke-Geschwind Wernicke’s area
- Controls language comprehension and processing of meaning
- Requires language to be coded in a specific way
Wernicke-Geschwind angular gyrus
- Provides visual language in the appropriate code to Wernicke’s area
Wernicke-Geschwind auditory cortex
- Provides spoken language in the appropriate code to Wernicke’s area involved in sensory processing of speech sounds
Wernicke-Geschwind motor cortex
- Involved in the production of articulatory movements
Wernicke-Geschwind arcuate fasciculus
- Bundle of axons linking Wernicke’s and Broca’s area
- Allows us to read aloud and repeat what others say
Wernicke-Geschwind repeating spoken words
- Auditory cortex processes speech sounds
- Meaning is accessed in Wernicke’s area
- Signals are transmitted via arcuate fasciculus to Broca’s area
- Broca’s area forms a speech-type representation of the word
- Instructions are sent to the motor cortex to execute action
Wernicke-Geschwind repeating written words
- Word is processed by the visual cortex
- Information is transmitted to the angular gyrus.
- The visual code is converted into a phonological in the angular gyrus
- The phonological representation is interpreted in Wernicke’s area
- Instructions are sent to the motor cortex to execute action
Conduction aphasia lesion
- damage to the arcuate fasciculus
conduction aphasia symptoms
- Good comprehension and production
- Repetition and reading aloud has paraphrasic errors and may fail with multisyllabic or nonsense words
Global aphasia
- damage to temporal and frontal areas
- poor comprehension, little speech and impaired repetition
Issues with Wernicke-Geschwind Model
- it is rare to find patients with damage confined to those regions
- the model is oversimplified
- functional distinctions aren’t mirrored in the brain
Issues with Wernicke-Geschwind Broca’s area
- it is only partly responsible for the ascribed function
- recent study of Broca’s patient showed damage to the insula cortex, other deep white and grey matter and the forebrain nuclei
Issues with Wernicke-Geschwind Wernicke’s area
- damage to Wernicke’s area alone produces mild symptoms
- initial swelling may cause the aphasia
- Visual information can reach Broca’s area without going via the angular gyrus and Wernicke’s area
Lichtheim’s model
- interpretation and comprehension of language required conceptual knowledge stored in a region outside Broca and Wernicke’s areas, interconnected by white matter tracts
- 3 types of disconnection damage could occur
Lichtheim damage to pathway from Wernicke’s to Broca’s areas
- this would be damage to the arcuate fasciculus
- causes conduction aphasia
Lichtheim damage to pathway from Wernicke’s to conceptual area
- impairs comprehension of speech (but not repetition)
-> transcortical sensory aphasia
Lichtheim damage to pathway from conceptual area to Broca’s
- similar to Broca’s aphasia, no repetition issues
obsessive repetition of heard phrases
-> transcortical motor aphasia
electrical stimulation methods
- Electrodes applied directly to the cortical surface whilst a patient was in surgery
(Penfield)
electrical stimulation LH
- aphasic arrest areas correspond roughly to Broca’s, Wernicke’s and angular gyrus
electrical stimulation of rostral regions
- strong stimulation- stop a patient talking
- weak stimulation- produce hesitant speech, mild anomia
- -> production issues
electrical stimulation of posterior regions
- speech arrest or words confusion
- -> comprehension issues
Right hemisphere linguistic function
- related to rhythm and expressive intonation in speaking and comprehension (surrounding meaning and emotional state of the speaker)