Week 5 Flashcards

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1
Q

What is an example of key genes being different in different populations of closely related species?

A

Humans, Apes, Howler monkeys, Old World monkeys trichromatic -They have 3 receptors in their retina allowing them to see all colours

New World monkeys dichromats and trichromats - every animal has the blue opsin, but red and green are encoded on separate X chromosomes

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2
Q

Why are Humans, Apes, Howler monkeys, Old World monkeys trichromatic?

A

Blue receptor gene is autsomal
X chromosome has both red and green

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3
Q

What can happen in Humans, Apes, Howler monkeys, Old World monkeys impacting being trichromatic?

A

XY = single allele – mutations are exposed
XX = “back-up” allele
XY more likely to have dichromatic mutations causing colour blindness

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4
Q

Why are new world monkeys dichromates and trichromates?

A

XY = always dichromatic blue autosomal AND (red or green) x chromosome
XX = can be dichromatic OR trichromatic

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5
Q

How did they test for the advantage to being trichromatic compared to dichromatic?

A

They got trichromatic and dichromatic marmosets and spread pink and green kix cereal on the ground.
They then recorded how well each monkey did at collecting the number of cereal
Then the did PCR to amplify the opsin region and sequenced the amplified DNA

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6
Q

What were the results of the experiment of trichrimates and dichrimate marmosets?

A

Both groups found green kix around the same trichromates slightly more
Dichromates found green and red kix about the same
Trichromates found pink kix a lot more than dichromatic marmosets

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7
Q

What conclusions can be drawn from this experiment about tri vs dichromates?

A

There is a definite link between being trichromatic and being able to distinguish orange/red food
In the forest the red fruit is the ripe fruit and therefore the ability to better distinguish red is advantageous
This provided an adaptive explanation for trichromatic colour vision

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8
Q

Why are there still dichromatic monkeys if being trichromatic is advantagous?

A

It would require a chance mutation restructuring an entire chromosome

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9
Q

What are the different behaviours for fruit fly feeding behaviours and what encoded for it?

A

Rovers = 70% of population
Sitters = 30% of population
Due to differences in the gene ‘foraging’
forR is the dominant allele
fors is recessive

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10
Q

Could fruit fly feeding behaviours change based on the environment?

A

However, rovers can become sitters, and vice versa given certain environmental conditions
So genetically encoded ‘innate’ behaviours can be variable, just like learned behaviours

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11
Q

What is an parenting behaviour in male Three-spined stickleback (Gasterosteus aculeatus)?

A

During breeding season, males defend territories, construct nests and attract mates
Females spawn in the nests
Males are the sole providers of parental care – they defend and tend their fertilised eggs
An important behaviour is “fanning” – oxygenates eggs

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12
Q

What can change male stickleback parenting behaviour?

A

Males adjust their care in response to many environmental factors – diet, algal blooms, temperature, oxygen availability, clutch size etc.
However, males show consistant individual differences in fanning behaviour

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13
Q

What is heritability?

A

The extent to which phenotypic variation in a population can be attributed to individual genetic differences

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14
Q

What is the heritability equation?

A

h^2 = V(inverse ^)A / V (inverse ^)P

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15
Q

What do each of the letters in the heritability equation mean?

A

h^2 = this is just the symbol for heritability, nothing is being squared! The value is always between 0 and 1
VA = additive genetic variance (variation in genotype)
VP = total phenotypic variance (variation in phenotype) (VP = VA + VE)

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16
Q

What happens if phenotypic variance is 0?

A

If there is no phenotypic variation, you can’t calculate heritability. The concept just doesn’t exist as you cant divide by 0

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17
Q

What happens if VE = 0 (identical environments)?

A

Identical environments –> 100% of trait variation attributed to genetics –> Heritability = 1.0
VP = VA + VE VE = 0 so VP = VA

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18
Q

What happens if VA = 0 (identical genetics)?

A

Identical genetics –> 0% of trait variation attributed to genetics –> Heritability = 0
VA = 0 0/x is always 0

19
Q

What does it mean if heritability = 1?

A

This does not mean that environment is irrelevant to a trait

20
Q

What does it mean if heritability = 0?

A

This does not mean genes are irrelevant to a trait just that there is no variation in the genotypes at this point.

21
Q

Whats difficult about measuring genes responsible for behaviour?

A

Its VERY difficult to identify genes responsible for a phenotype, which in this case is a behavioural trait, and therefore measure the genetic variation

22
Q

How did they investigate the impact on genes on behaviour?

A

Raise the offspring seperately from the parents, eliminaring phenotypic influence of the parents

23
Q

What is the logic behind the investigation?

A

If parents vary in fanning behaviour
And offspring are similar to their parents
Then we can conclude that genetic variation is causing at least some of the phenotypic variation

24
Q

How can you calculate heritability of a trait?

A

X axis = time parents sent fanning
Y axis = time offspring spent fanning
change in y /change in x = heritability
gradient y of 1 = heritability of 1

25
Q

Why is environment still important even if heritability is 1?

A

It is possible for fanning behaviour to be highly heritable, but also to be greater in offspring than the parent!
This is because the environment also has an effect on the trait – maybe the offspring experienced lower oxygen levels and so increased fanning to compensate

26
Q

How can you describe how environment has impacted a trait whilst showing heritability?

A

The intercept indicates a response to the environment
We can describe these regressions with y = mx + c

27
Q

How did they investigate the heritability of the fanning trait?

A

Bell et al collected breeding stickleback from the wild
Males were allowed to build nests, then a gravid female was introduced
Female removed after spawning, and male fanning behaviour observed
Fathers were removed before eggs hatched

28
Q

How heritable is the fanning trait?

A

ℎ𝑒𝑟𝑖𝑡𝑎𝑏𝑖𝑙𝑖𝑡𝑦=45/50=0.9

29
Q

Why is understanding parental behaviour heritability important?

A

There is a genetic component to parental care in this species that can be selected on, and strong selection could lead to rapid change

30
Q

How does selection act on a behavioural trait?

A

Difference between the mean of the population, and those with viable offspring is called the Selection Differential (S)
The mean of the time spent fanning for the offspring is to the right of the parental mean. The difference between the offspring and parent means is called the response to selection (R)

31
Q

If a heritability of a behaviour is 1 what does this mean for the relationship between the selection differential and response to selection?

A

If heritability is equal to 1, then the response will be the same as the selection differential.
High heritabilities combine with strong selection to produce rapid changes

32
Q

If a heritability of a behaviour is 0.3 what does this mean for the relationship between the selection differential and response to selection?

A

If heritabilty is 0.3 then the response to selection will be smaller than the selection differential (r will be 0.3).
Low heritabilities combine with strong selectrion to produce change but much more slowly

33
Q

If a heritability of a behaviour is 0 what does this mean for the relationship between the selection differential and response to selection?

A

A heritability of 0 means that there will be no response to selection

34
Q

What can also be used to apply to heritability for understanding?

A

Thinkng about heritability as selectabilty is useful for understanding evolution

35
Q

What is the difference between hertiability and genetic determination?

A

Heritability is a measure of what is associated with variation in a trait, not what causes a trait

36
Q

What is an example of heritability and genetic determination being different?

A

Most humans are born with 10 fingers and 10 toes - because our genetics determine our body plan
There is some variation though, some humans have missing digits or extra digits
Most of this variation can be explained by environment eg amputatiosn or thalidomide affecting faetal development

37
Q

What is heritability like on a temporal scale?

A

Heritability is not fixed
Heritability estmiates are calculated for a given population at a given time in certain environmental conditions

38
Q

What is investigating heritability of human behaviours?

A

Studies on heritability of human behaviour are difficult to conduct
People share genetics also usually share environments
We cant put clones of humans into controlled environmental conditions
We cant separate children from their parents and do a regression analysis
We rely on twin studies

39
Q

What the different types of twins and their genetic differences?

A

Monozygotic twins - identical DNA, no variation
Dizygotic twins - share 50% of genetic variation

40
Q

How can you look at the genetic differences between genetic behaviours?

A

Genetic variance (Monozygotic = 0, dizygotic = 0.5)
Shared environmental variants = family, parenting, home
Unshared environment environment = illness, random effects, individual perception

41
Q

How can you determine genetic inheritance of a human behaviour?

A

If monozygotic twins resemble each other more on a certain trait than the dizygotic twins do, that trait is genetically influenced

42
Q

What are examples of human behaviours an their genetic heritability?

A

IQ (age 5) = 22%
IQ (Age 18) = 82%
Major depression = 37%
Religousness = 30% - 45%
Personality = 40% - 60%

43
Q

Is the concept of heritability of human behaviour useful?

A

Yes, heritability estimates can be used to identify traits that have a genetic or environmental contribution. This could inform health studies
However, it doesnt tell us how much a trait is genetic and it doesnt explain differences between populations