Week 4 - Protein Flashcards
What are essential amino acids?
amino acids that cannot be synthesized and must be consumed in the diet
What are nonessential amino acids?
amino acids that can be made from others in the body
How many essential amino acids are there?
9
What are BCAAs?
branch-chain amino acids - leucine, isoleucine, and vailne
what is the primary protein structure?
a sequence of amino acids that forms one or more polypeptide chains
what is the secondary protein structure?
the coiling or folding of its polypeptide chains as a result of hydrogen bonding between amino acid chains
What is tertiary protein structure?
a folded three-dimensional shape caused by weak interactions between side groups
What is the quaternary protein structure?
the final 3d structure formed by all the polypeptide chains making up the protein
how is protein broken down in the mouth?
by mechanical digestion (chewing), no enzymes
How is protein digested in the stomach?
hydrochloric acid unfolds protein into long polypeptide chains
How do the pancreas and small intestine contribute to protein digestion?
they contribute enzymes that break polypeptide chains into free amino acids and smaller chains
How and where are amino acids absorbed?
they are absorbed by enterocytes that line the small intestine, then sent to the liver and released into circulation
What are the three fates for absorbed amino acids?
- incorporated into body protein or used to make other nitrogen compounds
- be oxidized for energy (deamination)
- contribute to the body’s glucose, ketone, and lipid pool
how is protein synthesized?
- transcription - DNA is split and copied to mRNA which is a recipe for protein
- translation - mRNA recipe is read to make a polypeptide chain or peptide