Week 4 - Protein Flashcards

1
Q

What are essential amino acids?

A

amino acids that cannot be synthesized and must be consumed in the diet

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2
Q

What are nonessential amino acids?

A

amino acids that can be made from others in the body

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3
Q

How many essential amino acids are there?

A

9

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4
Q
A
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5
Q

What are BCAAs?

A

branch-chain amino acids - leucine, isoleucine, and vailne

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6
Q

what is the primary protein structure?

A

a sequence of amino acids that forms one or more polypeptide chains

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7
Q

what is the secondary protein structure?

A

the coiling or folding of its polypeptide chains as a result of hydrogen bonding between amino acid chains

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8
Q

What is tertiary protein structure?

A

a folded three-dimensional shape caused by weak interactions between side groups

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9
Q

What is the quaternary protein structure?

A

the final 3d structure formed by all the polypeptide chains making up the protein

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10
Q

how is protein broken down in the mouth?

A

by mechanical digestion (chewing), no enzymes

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11
Q

How is protein digested in the stomach?

A

hydrochloric acid unfolds protein into long polypeptide chains

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12
Q

How do the pancreas and small intestine contribute to protein digestion?

A

they contribute enzymes that break polypeptide chains into free amino acids and smaller chains

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13
Q

How and where are amino acids absorbed?

A

they are absorbed by enterocytes that line the small intestine, then sent to the liver and released into circulation

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14
Q

What are the three fates for absorbed amino acids?

A
  1. incorporated into body protein or used to make other nitrogen compounds
  2. be oxidized for energy (deamination)
  3. contribute to the body’s glucose, ketone, and lipid pool
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15
Q

how is protein synthesized?

A
  1. transcription - DNA is split and copied to mRNA which is a recipe for protein
  2. translation - mRNA recipe is read to make a polypeptide chain or peptide
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16
Q

What happens if the body is missing a non-essential amino acid during synthesis?

A

the body will make it or obtain from the pool of amino acids in the liver via bloodstream

17
Q

What happens if the body is missing an essential amino acid during synthesis?

A

synthesis will stop and the incomplete protein will be tagged for break down - amino acids will be recycled to the liver pool

18
Q

What is kwashiorkor caused by

A

a lack of protein in the diet

19
Q

what are the effects of kwashiorkor?

A

change in skin hair color texture, fatigue, diarrhea, loss of muscle, failure to grow,
edema (swelling) of the ankles, feet, and belly
damaged immune system, etc

20
Q

what is phenylketonuria?

A

a rare inherited disorder that causes the amino acid phenylalanine to build up in the body

21
Q

how can phenylketonuria be treated?

A

a carefully monitored low protein diet, or dietary supplements without phenylalanine

22
Q

what are the effects of phenylketonuria?

A

cognitive damage and intellectual disabilities

23
Q

What is the protein RDA for adults?

A

0.8g/kg

24
Q

What percent of daily energy intake should be made up of protein?

A

10-35%

25
Q

What is an RDA?

A

amount of a nutrient that is thought to meet the needs of ~98% of the population

26
Q

How much protein should athletes take in per day?

A

~1.6g/kg body mass

27
Q

How much protein should elderly people have per day?

A

1-1.2g/kg

28
Q

What is the energy density of protein?

A

4kcal/g

29
Q

What are three roles protein has in physical activity?

A
  1. maximizing gains in muscle mass and strength
  2. preserving lean mass during calorie deficit weight loss
  3. structural benefits to tendon and bone
30
Q

What do BCAAs do in the body?

A

can be directly oxidized by muscle, and appear to play an important role in triggering MPS

31
Q

What population would benefit from BCAA supplementation?

A

vegans and vegetarians

32
Q
A
33
Q

Why is it important for vegetarians/vegans to combine a variety protein sources?

A

anima proteins contain high amounts of all amino acids, but some plant based sources have higher amounts of specific amino acids compared to others - so in order to get all amino acids, multiple sources must be used

34
Q
A