Week 4 - Lymphatic system Flashcards
Fluid regulation
Drains fluids from interstitium and returns to bloodstream
20L/day moves into interstitium
Only 17 L reabsorbed by capillaries
Interstitium
Connective tissue providing structural support to all the other anatomic components of the lung
How fluid regulation works
Tiny lymphatic capillaries soak up excess fluid
one-way valves and muscle pumps help to squeeze “lymph” back to venous system
Immune system
First line of defense
second line of defense
third line of defense
First line of defense
Chemical barriers - stomach acid, mucus membranes
Mechanical barriers - skin, hair
reflexes - coughing
Second line of defense
protective proteins
natural killer cells
- neutrophils, monocytes
inflammation and fever - macrophages
Third line of defense
T cells
B cells
Antibodies
Neutrophils
Type of WBC
Helps fight infection
Monocytes
type of WBC
Finds and destroys germs and eliminates infected cells
T cells
lymphocytes
Fights germs - cell to cell
protects from disease
become activated by specific pathogens
B Cells
B lymphocytes
creates antibodies
lifelong production
mature in bone marrow
Fights pathogens indirectly
Neutrophils, monocytes and macrophages work as…
antigen-presenting cells
Natural killer cells
NK
destroy virally infected/cancer cells
help to kill foreign cells by releasing toxins
Second line of defense
Interferon and compliment proteins
Interferon system
Compliment system
Interferon system
protein secreted by virus-infected body cells
cover surrounding cells to prevent virus from entering
boost immune system by activating macrophages and NK cells
Compliment system
Series of events causing body proteins to attach to pathogen causing lysis
lysis
disintegration of a cell by rupture of cell wall or membrane
4 types of T cells
Killer
helper
suppressor
memory