Week 4: Limbic system Flashcards

1
Q

What does the term ‘limbic’ mean?

A

Border or edge; describes the ring-like arrangement around the corpus callosum.

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2
Q

What are the four basic functions of the limbic system?

A

Olfaction, Memory, Emotions/Drives, Homeostasis.

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3
Q

What is the mnemonic for the limbic system functions?

A

HOME: Homeostasis, Olfaction, Memory, Emotions.

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4
Q

What structure is responsible for olfaction in the limbic system?

A

Olfactory cortex.

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5
Q

What limbic structure is involved in memory formation?

A

Hippocampal formation.

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6
Q

Which structure is responsible for emotions and behavioral responses?

A

Amygdala.

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7
Q

What limbic structure regulates homeostasis and autonomic control?

A

Hypothalamus.

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8
Q

What cortical structures are part of the limbic cortex?

A

Parahippocampal gyrus, cingulate gyrus, medial orbitofrontal cortex, temporal pole, anterior insula.

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9
Q

What are the three components of the hippocampal formation?

A

Dentate gyrus, hippocampus proper, subiculum.

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10
Q

What is the function of the hippocampus?

A

Consolidation of short-term to long-term memory.

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11
Q

Where is the amygdala located, and what is its function?

A

Temporal lobe; emotion processing, especially fear and aggression.

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12
Q

What are the roles of the thalamus and hypothalamus in the limbic system?

A

Relay and regulation of autonomic, endocrine, and emotional functions.

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13
Q

What basal ganglia components are connected to the limbic system?

A

Nucleus accumbens and ventral tegmental area (VTA).

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14
Q

What role does the nucleus accumbens play?

A

Reward, motivation, and addiction.

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15
Q

What is the function of the septal nuclei?

A

Associated with reward and reinforcement.

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16
Q

What brainstem area involved in dopamine release connects to the limbic system?

A

Ventral tegmental area (VTA).

17
Q

Which part of the basal forebrain is involved in the limbic system?

A

Cholinergic nuclei related to memory and arousal.

18
Q

What are the limbic functions of the cingulate gyrus?

A

Emotional regulation, pain processing, and behavior initiation.

19
Q

Which limbic structure is closely linked to the sense of smell?

A

Olfactory cortex.

20
Q

What is the general role of the limbic system in behavior?

A

Integrates emotion, memory, motivation, and autonomic responses.

21
Q

What are the two main components of the limbic cortex seen on the medial view?

A

Cingulate gyrus and parahippocampal gyrus.

22
Q

What is the uncus and where is it located?

A

A visible bump on the anterior medial parahippocampal gyrus.

23
Q

What gyri does the cingulate gyrus continue into anteriorly and inferiorly?

A

Subcallosal gyrus and paraterminal gyrus.

24
Q

What limbic cortex region is linked with social behavior?

A

Medial orbitofrontal cortex.

25
What clinical case is associated with damage to the orbitofrontal cortex?
Phineas Gage – personality change and inappropriate behavior.
26
What are the effects of prefrontal lobotomy on behavior?
Inappropriate behavior and lowered moral standards.
27
What function is associated with the anterior part of the insular cortex?
Olfaction, nausea, vomiting, and disgust.
28
Where is the entorhinal cortex located?
Anterior portion of the parahippocampal gyrus.
29
What are the functions of the entorhinal cortex?
Memory processing and olfactory input; gateway to the hippocampus.
30
What structure is considered part of the olfactory cortex and memory system?
Entorhinal cortex.
31
What part of the limbic cortex is associated with sadness and depression?
Subcallosal part of the cingulate gyrus.
32
Which limbic structure contains the "inhibitory control center" or "second thoughts"?
Anterior part of the cingulate gyrus.
33
What is the function of the parahippocampal gyrus?
Memory encoding and retrieval, especially spatial memory.
34
What role does the cingulate gyrus play in emotion?
Regulates emotions, pain, and behavioral outcomes.
35
What limbic structure acts as a bridge between emotion and action?
Cingulate gyrus.