Week 4 - Healthcare infections Flashcards

1
Q

What % of patients get HCI?

A

-8%

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2
Q

How do HCI have economic impact on NHS?

A

-If the pt stay is extended over the trimpoint then NHS does not get paid

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3
Q

What are the mose commonly acquired HCI?

A
  • C.diff

- Norovirus

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4
Q

What are the most common healthcare viruses?

A
  • Norovirus causing gastroenteritis

- Influenza

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5
Q

How is norovirus spread?

A

-Faecal-oral, person-person, aerosolization

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6
Q

What virus causes winter vomiting infection?

A

-Norovirus

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7
Q

What is the treatment for norovirus?

A
  • Usually self-limiting

- Fluid resuscitation in extreme cases

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8
Q

What is MRSA?

A

-Methicillin-Resistant staphylococcus Aureus

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9
Q

Why does MRSA have a high mortality?

A

-Develops in hard to treat places eg Heart valves

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10
Q

What are the common signs of C diff infection?

A
  • Diarrhoea
  • Fever
  • Abdo cramp
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11
Q

Why is c.diff associated with hospitals?

A

-It is a spore-forming bacteria which can survive on objects and surfaces in harsh conditions which are then ingested and become vegetative

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12
Q

What is the gram status of E.coli and Klebsiella?

A

-Gram negative

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13
Q

When are fungi seen in healthcare infections?

A

-In the immunocomprimised patient

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14
Q

What people are at risk of getting HCI?

A
  • Extremes of age
  • Smoker
  • Surgical patient
  • Emergency admission
  • Immunocomprimised
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15
Q

Why are premature babies at risk of HCI?

A
  • Poorer immune system

- Decreased skin quality

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16
Q

What patient factors can you apply to prevention and control of HCI?

A
  • Interactions with other patients, HCP, visitors
  • MRSA screen and antimicrobial prophylaxis if appropriate
  • Disinfectant bodywash
  • Optimise patient conditions eg decrease smoking, increase nutrition
  • Isolation of infected patients/protection of susceptible patients
  • Barrier nursing
17
Q

What pathogen factors can you apply to preventing and controlling HCI? Use C.diff as an example

A
  • Virulence factors affect prevention and control eg c.diff is opportunistic and toxin production is in the stationary phase so the infection is not recognised until well established and already contagious
  • High virulence -> single use equipment
18
Q

What practice factors can you apply to prevention and control?

A
  • HCP training on prevention and control

- Government policies and their implementation eg hand hygiene

19
Q

What place factors can you apply to prevention and control?

A
  • Space/layout of toilets and handwash basins
  • Furniture and furnishings to be easy clean, disinfectant use
  • Medical devices for single use only or to be sterilised
  • Good food hygiene and kitchen facilities
20
Q

What would you do if someone is highly infectious in hospital?

A
  • Isolation room with toilet/commode
  • PPE including apron and gloves
  • Barrier nursing
21
Q

Why is the use of some antibiotics liked to c.diff infections? Which abx?

A
  • Reduce the number of normal flora giving C diff the opportuity to grow
  • Ceftriaxone
22
Q

What toxins are produced by c.diff? How do they infer virulence?

A
  • Enterotoxin A -> alters the permeability of the intestinal wall (inflammation)
  • Cytotoxin B -> cytotoxic to cells
23
Q

What is the gram status of C.diff?

A

-Gram positive bacilli

24
Q

Name some other clostridium species apart from C.diff

A
  • C. tetani
  • C.Pefringes
  • C.botulinum
25
Q

Why is india associated with high rates of antibiotic resistance?

A

-Abx are available over the counter and there is no prescription control resulting in over-use of abx and non-compliance

26
Q

What are the complications associated with norovirus?

A
  • Dehydration
  • Malnutrition
  • Death
27
Q

What is a healthcare infection?

A

-Infections arising as a consequence of providing/receiving healthcare which is neither present nor incubating at time of admission (ie onset must be after 48 hours)