Week 4 - GI Flashcards
What are the defense mechanisms of the stomach?
- Mucosal barrier
- Buffer of bicarbonate
- Blood flow to help heal injured cells
- Prostaglandins to protect epithelial lining
What does PG do in the stomach?
Increase mucus production, decrease acidity
What is PUD?
PUD is when there is a breakdown in one of the stomach’s defense mechanisms.
Direct contact point between stomach acid in epithelial cells
Usually as a result of H. pylori which chews through protective mucosal layer
Hard to get mucosal layer fixed without eradicating H pylori with appropriate meds
Prior to the administration of bismuth, the nurse should perform
percussion of the abdomen, auscultation of the abdomen, palpate the abdomen
Can bismuth be given PR?
No, only PO
Would it be safe to give bismuth to someone with an aspirin allergy?
No - an allergy to aspirin is a contraindication
Are antiandrogen effects of ranitidine are reversible?
Yes
What cells within the gastric lining does ranitidine work on?
Parietal cells that release acid and intrinsic factor
Clients placed on long term PPI therapy are at greater risk for
Cancer, Increased risk of dementia, Electrolyte imbalance, Rebound reflux
Contraindications for sucralfate
previous allergic reaction to sucralfate
Bowel obstruction
Why should you not give sucralfate with food?
Food alters the stomach’s pH and the gel like substance might not form if the pH is off
Why should you not give antacids with sucralfate?
Antacids alter the stomach’s pH potentially preventing the formation of the gel like substance
Without the correct education, a patient is at risk for what due to the side effects of metoclopramide?
dehydration due to diarrhea. Also sedation could –> decreased water intake
Metoclopramide works mainly by its ability to what?
increase gastric contraction
Metoclopramideis indicated in the treatment of what disorders?
GERD, N/V, Diabetic associated gastroparesis
