Week 4 Flashcards
How much of the adult body, lean body tissues, and fat mass are made up of water?
Adult body = 50-60% water
Lean body tissues (muscle, heart, liver) = approx 75% water
Fat mass = approx 5-10% water
What are key functions of water
Functions: nutrient transport (blood and plasma is water), protection (tears, lubrication, synovial fluid), temperature regulation, biochemical reactions, (hydrolysis is splitting something with water) medium for reactions
Intra and extracelluar fluid in relation to water content
Intracellular fluid – 2/3 of total body water content, but in context of hydration status, the extracelluar fluid is most important
Extracelluar fluid – contains the interstitial fluid (between cells) and blood plasma
What is in fluid (water) balance (euhydration)
Fluid gain = fluid loss
How do you gain, and hoe do you lose fluid?
Fluid gain – drink, food, metabolic (e.g. breakdown of glycogen). Usually matched with respiration in fluid loss.
Fluid loss – respiration, skin, feces, urine
If someone lost 1000ml of fluid through exercise, what would they be in?
And what would kick in to restore euhydration?
Extra 1000ml fluid loss from exercise meaning negative fluid (water) balance (dehydration, hypohydration). If they drunk/ate 1000ml, then they would return to euhydration. Thirst and hunger kick in to regulate fluid balance.
What is net body water balance
Net body water balance is the difference between fluid water gain (intake and production) and fluid loss.
Is net water body balance well maintained on a day to day basis?
What challenges it?
Typically, well maintained on a day to day basis (within 1% body mass) (thirst and hunger drives).
Net body water balance can be challenged during period of high sweat rates
What is dehydration or hypohydration
> 2% body mass reduction
Body water deficit greater than normal daily fluctuation
How would you statically assess hydration status in someone?
Best static physiological index of hydration status is plasma osmolality – a measure of the total dissolved particle concentration in mOsm/kg
Plasma osmolality going down is related to dehydration
T or F?
F - Increased Osm means dehydration - any value over 295 mOsm/kg is related to dehydration
(Typical value is 275-295)
How can dynamic dehydration be tracked?
Body mass change – through sweating
Plasma osmolality
Urine specific gravity – urine density relative to water – water = 1.00. euhydrated at 1.003-1.035 (Eu)
What is Reference change value
Reference change value (RCV) - change from baseline to after exercise – probability that you will be dehydrated
As dehydration liklihood increases, what happens to plasma osmolality, % body mass loss, and urine specific gravity?
Plasma osmolality increases with dehydration probability
Urine specific gravity also increases
% body mass loss also increases. 2% body mass loss relates to 90% chance you are dehydrated
Why do we sweat?
For every L of oxygen consumed 4kcal of heat is produced and only about 1kcal is used to perform mechanical work (most is wasted on heat production)
Most of this heat is passed to body core via bloodstream
Hypothalamus senses increase in body and skin temperature
Responds to increase blood flow to skin and initiate sweating to dissipate heat through sweat. Preventing excessive rises in temp (hyperthermia).