Week 2 Flashcards
Main functions of carbohydrates
-provide energy for physical activity and muscle contraction
-provide energy for the central nervous system and the brain to carry out cell signalling
Link between glucose metabolism and the brain
Brain has preference for glucose metabolism (comes from breakdown of carbs). Body places high priority on maintaining glucose levels to a narrow range due to its link with the brain.
What challenges the ability to maintain blood glucose?
PA and muscle contraction places a high demand on cho metabolism – trade off between maintenance of blood glucose for brain and muscle increasing turnover of fuel – challenging ability to maintain blood glucose.
How much cho stores do we have compared to fat stores?
And why are cho stores preferred as ex intensity increases?
CHO stores are extremely limited compared to the vast amounts of fat that we have available in the body
Increasing ex intensity leads to greater cho oxidation as it generates atp faster than is possible through fat ox.
Key sources of carbohydrates in the body
Blood glucose – must be maintained to a narrow range (3-5g)
Liver glycogen – gluconeogenesis keeps this liver glycogen sufficient, also topped up via feeding. This trickles into the blood glucose store to keep it maintained.
Muscle glycogen
What happens to the contribution of blood glucose and muscle glycogen as exercise intensity increases/
During exercise intensites of over 70% vo2 max, increase in cho’s ability to provide atp, and decline in fat – increase in contribution of blood glucose and muscle glycogen.
How does the muscle affect blood glucose from deviating from its narrow range?
Muscle contracting, extracting glucose from blood to provide energy it needs. This means blood glucose may fall.
Due to the muscle contraction extracting blood glucose, what other mechanism ensures the narrow range of blood glucose is maintained?
Liver pumps out more glucose. Exercise increases liver glucose output in an intensity dependent manner. Close matching between muscle glucose uptake and liver glucose output
How does blood glucose change in response to liver glucose output and muscle uptake?
Blood glucose tries to stay the same – however, sometimes goes up slightly due to adrenalin. (more glucose pumped by liver than muscle uptake)
However, this is only possible for as long as the liver has glycogen. Therefore, longer periods of ex, cause glycogen to run out, meaning blood glucose might fall.
How are fatigue and muscle glycogen related
Exhaustion was associated with depletion in muscle glycogen.
What analogy is used to describe muscle glycogen during exercise
Muscle glycogen can be seen as a petrol tank
Lots of fuel = lots of muscle glycogen, but how long the journey is determined by the fuel. How long you exercise for = how long it takes for MG to run out.
How is blood glucose related to cho oxidation
What happens as a result?
Decline in blood glucose during placebo trial coincides with low rates of cho oxidation. This makes fat the primary source, meaning we start to feel fatigued, as atp production doesn’t meet atp demand.
What does supplementation of cho during exercise (e.g. sugary drinks) do to muscle glycogen depletion?
Supplementation of cho during ex (e.g. sugary drinks) does not slow muscle glycogen depletion. Rate of muscle glycogen depletion is the same regardless of consumption of cho or not. It slows liver glycogen depletion, not MG depletion.
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What are daily carbohydrate recommendations based on?
They are based on body weight, not % of energy intake
e.g. 5 g/kg/d NOT 50% of energy intake