Week 35/36 - stress Flashcards

1
Q

Contractiemechanisme glad spierweefsel

A

actine filamenten aan dense bodies, myosine met sidepolar kruisbruggen trekken actine naar zich toe

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2
Q

Verschillen glad en skeletspierweefsel

A

langer vasthouden -> minder energie, sterkere contractie
Ca²⁺ komt ook uit extracellulaire vloeistof
goed beïnvloedbaar door hormonen

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3
Q

Contractie glad spierweefsel

A

Ca²⁺ -influx -> bindt aan calmoduline -> fosforylatie lichte keten myosine -> myosine bindt aan actine

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4
Q

relaxatie glad spierweefsel

A

Ca²⁺ -efflux + myosine fosfatase

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5
Q

Effect hormonen op glad spierweefsel

A

openen/ sluiten kanalen
verminderen Ca²⁺ concentratie sarcoplasma

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6
Q

pre- en postganglionisch (cholinerg of adrenerg)

A

pre = kort en cholinerg (myelinated -> PS sneller)
post PS = cholinerg
post S = adrenerg (behalve zweetklier)

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7
Q

neurotransmitter secretie

A

AP -> Ca²⁺ -influx -> varocisiteiten -> exocytose -> binden receptor -> verandering membraanpermeabiliteit/ aanzetten second messenger

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8
Q

HPA-axis

A

hypothalamus -(CRH)> hypofyse -(ACTH)> adrenale medulla -(cortisol)>

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9
Q

3 gebieden adrenale medulla:
- zona glomerulus
- zona fascicularis
- zona reticularis

A
  • aldosteron (angiotensine II en kalium)
  • cortisol (ACTH)
  • androgeen
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10
Q

synthese corticosteroïden

A

cholesterol

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11
Q

functies mineraalcorticoïden (aldosteron)

A
  • meer K-secretie en Na-reabsorptie
    -verhoging ECV en bloeddruk
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12
Q

functies glucocorticoïden (cortisol)

A
  • meer vrij glucose (gluconeogenese)
  • meer vrije aminozuren
  • meer vetverbranding
  • stress-resistensie
  • anti-inflammatoir
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13
Q

Criteria overspannen

A
  • > 3 symptomen
  • controleverlies
  • beperkingen
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14
Q

Criteria burn-out

A

> 6 maanden overspannen + vermoeidheid op voorgrond

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15
Q

Benaderingen stress

A
  • stimuli = belasting van individu door omgeving
  • reactie = fysiologische reactie
  • transactie = in ruil voor een ervaring
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16
Q

Coping strategiën

A
  • probleemgericht (aanpak)
  • emotiegericht
  • ontwijkend