Week 3 UWorld and Cases 9-12 Flashcards
what is a severe toxicity of oxytocin to be aware of?
hyponatremia
how does oxytocin cause hyponatremia?
can act as a vasopressin analog and stimulate the collecting ducts
of trichomonas, gardnerella and candida, which vaginosis occurs with normal pH? what is normal ph?
candida…3.8-4.5
what is difference in superficial wound dehiscence and deep wound dehiscence?
deep involves the rectus fascia and is a surgical emergency whereas superficial is just subcutaneous tissue and is managed with regular dressing changes
what is a sign for primary ovarian insufficiency?
no bleeding with progesterone withdrawal
what are some risks for primary ovarian insufficiency?
cancer drugs, radiation, Turner, fragile X carrier
what bHCG levels indicate a molar pregnancy?
greater than 100,000 IU/L
what are some risks for postpartum urinary retention?
epidural is number 1, laceration, assissted vaginal delivery, c sxn
define post partum irinary retention?
6 hrs post op no void
what is a common cause of postpartum urinary retention?
pudendal nerve injury
what determines which pill to give in hormone replacement for menopausal symptoms?
if there is a uterus or not
if menopausal woman has uterus what do you give?
estrogen and progestin
if menopausal woman doesnt have uterus what do you give?
estrogen only
at what age are endometrial cells on pap smear concerning? what is next step?
45+…need to biopsy the endometrium because there may be hyperplasia or cancer
in addition to tampon use, what is another case for females to get toxic shock syndrome from staph a?
post delivery or surgical incision repair
what is rx for toxic shock syndrome?
clindamycin and vancomycin
what are signs of toxic shock syndrome?
macular rash including hands and feet with high fever and hypotension
what are risks to fetus with chorioamnionitis?
preterm birth, pneumonia, encephalopathy
what are the signs in mom with chorioamnionitis?
fever with tachycardia or leukocytosis or purulent amniotic fluid
what is lactational mastitis? who gets it?
moms with first pregnancy over 30 yo…staph A gets into the breast
what are sx of lactational mastitis?
fever, malaise, tenderness an erythema
what is a complication of lactational mastitis?
breast abscess
how do you dx lactational mastitis and breast abscess?
US
how do you treat lactational mastitis?
dicloxacillin or cephalexin
how do you treat a breast abscess?
drainage
mom with GBS has penicillin allergy, what is option for rx?
cephazolin
are NSAIDs used in pregnancy>
typically not
what is the first stage of labor?
onset contractions until cervix fully dilated
what is full dilation of cervix?
10 cm
what are the two parts of the first stage of labor?
latent and active phase
what is the latent phase of the first stage of labor?
cervix going from 0-6cm dilation
what is the active phase of the first stage of labor?
cervix going from 6 cm to 10 cm dilated at 1cm/2hr
what is first line treatment for acute cystitis of asymptomatic bacteruria in pregnancy?
nitrofurantoin…
what should you do in follow up with patient who had either acute cystitis or asymptomatic bacteruria in pregnancy?
another urine culture in a couple weeks
where is bartholin duct cyst located?
posterior vaginal introitus, posterior to labia majora
/what are sx of bartholin duct cyst?
soft mobile non tender cystic mass
what is a complication of a bartholin duct cyst?
development of infected abscess
three conditions that increase risk for preeclampsia?
SLE, chronic HTN, diabetes and twins
what should be done at first prenatal visit with a patient at higher risk of developing preeclampsia
go ahead and get a baseline urine protein 24 hours
what is the main difference between a breast abscess and inflammatory breast cancer?
cutaneous edema and skin dimpling are seen in inflammatory breast cancer
what is active phase protraction?
when cervix is dilating less than a cm every 2 hrs btween hrs 4 and 8 of labor
what is a common cause of active phase protraction?
cephalopelvic disproportion
what is cephalopelvic disproportion?
head too big for moms pelvis
what are some other risk factors for active phase protraction?
advanced maternal age
obesity
excessive wt gain
inadequate contractions
what is vaginal hematoma? when does it occur? why?
bleeding from injured uterine arteries during delivery
what are the signs of vaginal hematoma?
low bp, tachy, vaginal mass, minimal bleeding
where does bleeding occur in vaginal hematoma?
paravaginal space…so it is occult bleeding
what are two risks for vaginal hematoma?
operative vaginal delivery and large baby (8.8lbs)
if patient develops significant proteinuria and elevated creatinine prior to 20 weeks gestation what is most likely underlying cause?
not preeclampsia…most likely is underlying renal pathology like diabetic nephropathy
what are two treatment options for stress urinary incontinence?
urethral sling and pelvic floor exercises
what is aromatase deficiency?
when female karyotype cannot convert testosterone into estrogen
what are signs of aromatase deficiency?
normal internal female genitalia with external virilization, normal XY karyotype, low estrogen
what are lab values of FSH/LH and estrogen in puberty with aromatase deficiency?
high FSH and LH low estrogen
what happens in pregnancy to mom with aromatase deficiency?
she can be masculinized
are vaginal petechiae a common menopausal exam finding?
yes..
what is the test to determine dose of rhogam to give mom?
Kleihauer Betke test
how do you manage delivery of fetus that is non viable? what about if pre term?
you focus on the well being of the mom…allow for delivery to occur spontaneously because this is safest to mom…even if it is preterm
what testing should be done to fetus with intrauterine fetal demise?
autopsy and genetic testing
what testing should be done to mom in intrauterine fetal demise?
Kleihauer Betke test and antiphospholipid antibody screen
other than mom and fetus, what else should be checked in intrauterine fetal demise?
placenta
what are some risks for uterine atony?
prolonged labor, assisted delivery, macrosomia, retained placenta
what are signs of uterine atony?
PPH and enlarged soft boggy uterus
what is first line rx for uterine atony
massage and oxytocin
what is second line rx for uterine atony?
trenaxemic acid
clear cervical mucus is what?
mucus associated with ovulation
what happens if epidural is accidentally put into vasculature?
get CNS overactivity…can be fatal
what are signs of epidural accidentally put into vasculature?
perioral numbness
metalic taste
tinnitus
seizures
how long after delivery must one go without voiding to have postpartum urinary retention?
6hrs
what is rx for postpartum urinary retention?
foley catheter
what is level of thrombocytopenia that is normal in pregnancy?
100-150
what level of thrombocytopenia in pregnancy is concerning for preeclampsia or HELLP?
100 or less
what is a luteoma in pregnancy?
solid mass of ovaries that is stimulated by hcg and secretes androgens
what can happen to mom and fetus with luteoma in pregnancy?
virilization
what is a theca lutein cyst in pregnancy?
uni or bilateral cyst of ovary stimulated by hcg
what can happen to mom with theca lutein cyst in pregnancy>
virilization
what is main difference between theca lutein cyst and luteoma in pregnancy?
luteoma is SOLID
what is rx for theca lutein cyst and luteoma in pregnancy?
watchful waiting
what is treatment of cornual ectopic pregnancy?
not methotrexate…need to do surgery to minimize risk of rupture
what are some contraindications to methotrextate therapy for ectopic pregnancies?
breastfeeding
anemia and immunosuppression
pulmonary disease
hepatic or renal disease that would affect clearance
what level hcg do you want to start methotrexate therapy for ectopic?
LESS than 5000
what is reversal agent of Mg?
Ca2+
what is treatment for eclampsia?
immediate Mg and c sxn
what is treatment for preeclampsia with severe features?
Mg and induced delivery
what should fibrinogen levels be in pregnancy?
elevated
what should D dimer level be in pregnancy?
elevated
what two lung volumes change in pregnancy?
increased tidal volume and decreased FRC
what is a PUBS test? what does it test for?
percutaneous umbilical blood sampling for fetal anemia
what is a TCD test ? what does it screen for?
transcranial doppler that screens for fetal anemia
what is an indication to perform either a trans cranial doppler or a PUBS?
if you think theres a chance of alloimmunization
when can CVS be performed?
10 weeks and after
when can amniocentesis be performed?
16 weeks and after
when can PUBS be performed?
between 20 and 34 weeks
what is the rule with ultrasound dating in each trimester?
1st tri +- 1 week
2nd tri +- 2 weeks
3rd tri +- 3 weeks
what is preventative med used for migraines in prgenancy?
propanolol