Week 1 UWorld and Case Files 1-4 Flashcards

1
Q

when does risk of MS onset increase in women? signs?

A

post partum period…fatigue and CNS symptoms

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2
Q

2 main signs on cerebral venous thrombosis in women

A

HA and papilledema

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3
Q

2 imaging modalities for CVT

A

CT first then MR venography

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4
Q

what is management of Ovarian torsion?

A

diagnostic laporoscopy

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5
Q

common cause of ovarian torsion?

A

ovarian mass

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6
Q

what is treatment of opioid dependent pregnant patients? why?

A

methadone throughout pregnancy…better than detox and medication withdrawal management because this has increased risk of relapse

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7
Q

signs of malignant hyperthermia

A
hypercapnea
tachypnea
tachycardia
myoglobinuria
muscle rigidity
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8
Q

symptom of uterine rupture? risk for? manage?

A

sudden abdominal pain in labor…risk is prior uterine surgery…manage with immediate c xsn

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9
Q

2 complications of uterine rupture in labor?

A

cord compression…decreased fetal HR

hypoxic placenta if placenta involved

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10
Q

three parts of initial eval of patient with AUB-O

A

CBC, preg test, coag studies

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11
Q

rx for AUB-O if patient is stable?

A

high dose estrogen will control bleeding…if contraindicated can give progesterone

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12
Q

when does peripartum cardiomyopathy occur? Signs? management?

A

happens in last month of preg or 5 mos after delivery
signs are those of HF, mitral regurg
manage with echo and follow…rx like HF

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13
Q

what is murmur associated with peripartum cardiomyopathy

A

mR

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14
Q

number one cardio contraindication to pregnancy

A

mitral stenosis that is symptomatic

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15
Q

5 cardio contraindications for pregnancy

A

symptomatis MS and AS
PAH
LVEF less than 30%
bicuspid AV with enlarged AA

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16
Q

what can often co occur with granulosa cell tumor? why? how to evaluate for it?

A

endometrial hyperplasia/cancer because of the increase inestrogen from the tumor…so do biopsy to rule in/out

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17
Q

what is AFLP?

A

acute fatty liver of pregnancy

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18
Q

when does AFLP occur?

A

in 3rd trimester

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19
Q

sx and management of AFLP

A

hypoglycemia, elevated liver enzymes and bilirubin

manage by immediate delivery

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20
Q

complication of AFLP?

A

DIC

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21
Q

Most common SE of tamoxifen?

A

hot flashes

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22
Q

what qualifies as recurrent cystitis in women?

A

2 infxns in 6 mos or 3 in a year

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23
Q

what is good way to treat recurrent cystitis in women if happening post intercourse?

A

postcoital abx

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24
Q

what is a urethral diverticulum?

A

urethral outpouching that can cause an anterior vaginal wall mass that is tender

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25
Q

what is a prolonged postoperative ileus?

A

greater than 72 hours after surgery the bowel still isnt moving…no flatus

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26
Q

signs of prolonged postoperative ileus

A

no flatus..abdominal distension on Xray and N/V

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27
Q

tubovarian abscess is from what? what does it look like?

A

from PID…is a complex multiloculated adnexal mass

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28
Q

what is prevention rx for preclampsia?

A

12 weeks gestation give low dose aspirin

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29
Q

what imaging is done for any unilateral spontaneous nipple discharge?

A

always US…if older than 30 then add on mammogram too

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30
Q

how does uterus feel in adenomyosis?

A

bulky and tender

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31
Q

how does uterus feel in fibroids?

A

irregularly enlarged

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32
Q

2 signs of uteroplacental insufficiency in late/post term pregnancies

A

fetal decelerations in non stress test and largest pocket of amniotic fluid on US is less than 2 cm

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33
Q

what is contraindicated in females with migraine history? why?

A

estrogen containing contraception because of increased risk of thrombotic stroke in patients with migraine…and estrogen increases that risk further

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34
Q

what is cutoff for fetal bradycardia/tachycardia?

A

110 and 160

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35
Q

when is non stress test done on fetus?

A

when there is concern for lack of fetal mvmnt, hypoxia and acidosis

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36
Q

what normally happens with non stress test in fetus?

A

when fetus moves…HR increase

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37
Q

if HR does not increase in non stress test, what is MC cause of this finding?

A

quiet sleep cycle in fetus…extend study

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38
Q

short interval between pregnancy is considered how long? what are risks?

A

6-18 mos

risk for PPROM, maternal anemia, pre term delivery and low birth weight

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39
Q

if corpus luteum is lost before week 10 of gestation what do you need to do?

A

give progesterone replacement

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40
Q

what is reason to check fetal heart rate patterns during delivery?

A

to be aware of brain hypoxia

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41
Q

what is category 1 of fetal heart rate patterns?

A

110-160 BPM

with variability and no late deceleration

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42
Q

what is category 2 of fetal heart rate patterns?

A

in between 1 and 3

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43
Q

what is category 3 of fetal heart rate patterns?

A

absent variability with late decels, variable decels or bradycardia

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44
Q

what is rx for cat III fetal heart pattern?

A

stop uterotonics…administer oxygen and reposition mom to see if that helps…if not go direct to c sxn

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45
Q

what is second stage of labor? when is it arrested?

A

second stage is after full cervical dilation and effacement and actively pushing…if actively pushing for 3 hrs with no fetal change then in second stage arrest

46
Q

what is cause of gestational diabetes? when to screen?

A

human placental lactogen secretion

screen at 24-28 wks

47
Q

what is first and second line rx for gestational diabetes?

A

1st is diet and exercise

2nd is insulin followed by metformin and glyburide

48
Q

what is shoulder dystocia?

A

impaction of fetal anterior shoulder into moms pubic symphis…head is out

49
Q

what is first thing to do for shoulder dystocia?

A

elevate legs and flex hips then apply suprapubic pressure

50
Q

what are screenings at 12 weeks gestation?

A

HIV, syphilis, blood types, nuchal translucency and PAPP-a

51
Q

what does nuchal translucency and PAPP- a test for at 12 weeks?

A

T21

52
Q

is weight gain common with OCPS?

A

NO…just depo

53
Q

when do you need backup for OCPs?

A

if you start more than 7 days after last period

54
Q

what are some dietary changes to help with first tri N/V?

A

small frequent meals low in fat with ginger root and ale

55
Q

what are two supplements for N/V in 1st tri?

A

B6 and doxylamine

56
Q

what are anti emetics for N/V in 1st tri?

A

metocloprmaide and pomethazine

57
Q

what abx decrease OCP effectiveness?

A

rifamipin, rifabutin and rifamixin

58
Q

patient in labor develops fever and has prolonged membrane rupture, what is diagnosis?

A

chorioamnionitis

59
Q

what is rx for chorioamnionitis?

A

continue labor and give broad spectrum abx

60
Q

a fever in immediate post partum setting should be considered as what?

A

endometritis

61
Q

what is the bishop score?

A

score to determine need for cervical ripening agents…takes dilation, effacement and position into account

62
Q

what are some ways to induce labor without medication?

A

nipple stimulation
amniotomy
membran stripping

63
Q

what is most effective labor analgesia agent?

A

epidural, pudendal nerve blocks are useful in second stage of labor

64
Q

name the four risks of assisted vaginal delivery

A

shoulder dystocia, facial nerve palsy, cephalohematoma and brachial plexus injury

65
Q

4 drugs for postpartum hem

A

oxytocin
carboprost
methylergonivine
misoprostol

66
Q

what is contraindication to carboprost?

A

asthma

67
Q

what is contraindication to methylergonivine

A

HTn

68
Q

what does fetal fibronectin test for?

A

it is a test to determine likelihood of preterm delivery…if negative then good

69
Q

what are tocolytic meds used for?

A

prevention of pre term labor

70
Q

name the tocolytics

A

nifedipine
magnesium sulfate
prostaglandin inhibitors

71
Q

effects of magnesium toxicity?

A

somnolence, loss of DTRs and respiratory depression

72
Q

risk for magnesium toxicity?

A

renal insufficiency `

73
Q

wht age for significant fertility decline?

A

35…minimal ovarian reserve

74
Q

what is infertility at 35 or older likely from ?

A

diminshed ovarian reserve

75
Q

what do you do if patient has seizure from eclampsia in labor?

A

prompt delivery

76
Q

what two things elevated in T21? what is low?

A

hcg and inhibin a

afp is low

77
Q

what are levels of afp, hcg and estriol in T18?

A

all low

78
Q

what is rx of uterine inversion?

A

manual replacement of uterus

79
Q

what causes uterine inversion?

A

excess fundal massage and traction on umbilical cord

80
Q

most common cause of term oligohydrmnios?

A

rupture of membranes

81
Q

what are signs and symptoms of chorioamnionitis?

A

fever, tachycardia, leukocytosis, N/V and uterine tenderness

82
Q

what are two risks for chorioamnionitis?

A

PPROM and prolonged rupture of membranes

83
Q

what is rx for chorioamnionitis?

A

abx and delivery

84
Q

Define pprom

A

preterm prelabor rupture of membranes before week 37

85
Q

three risks for PPROM

A

GU infxn, antepartum bleeding and prior PPROM

86
Q

how do you manage PPROM?

A

if less than 34 wks give abx and steroids if more then deliver

87
Q

risk factors for cervical cancer?

A

immunosupression, HPV, lot of sex partners, early sex, tobacco

88
Q

risk factors for ovarian cancer?

A

family history, emdometriosis, early menarche and later menopause

89
Q

risk factors for endometrial cancer

A

annovulation and obesity

90
Q

what four things to give in preterm labor?

A

ampicillin
steroids
magnesium sulfate
tocolytics

91
Q

why is magnesium sulfate given in pre term labor?

A

because it is neuroprotective against CP

92
Q

what is rx for labial adhesion?

A

estrogen cream

93
Q

who gets labial adhesions? sx?

A

2-3 yo girls

usually asymptomatic but can cause GU infxn and be itchy

94
Q

symptoms of inflammatory breast cancer?

A

peau de orange, edema, erythema and lymphadenopathy

95
Q

classic finding in inflammatory breast cancer?

A

peau de orange…dimpling of skin with edema

96
Q

what is rx for inflammatory breast cancer?

A

mastectomy and chemo

97
Q

how to dx inflammatory breast cancer?

A

punch or core biopsy

98
Q

three common reasons for elevated AFP?

A

NTD,

gastric wall defect like omphalocele and multiple gestations

99
Q

what is TTTS?

A

twin twin tranfusion syndrome

100
Q

explain what happens in TTTS?

A

anastomosis btw umbilical artery of one twin and vein of other twin so one twin loses blood and gets anemic and oligohydramnios while other gets polycythemia and polyhydramnios

101
Q

what must be present to have TTTS?

A

monochorionic twins

102
Q

what is treatment for endometrial hyperplasia if patient desired future preg?

A

IUD with progesterone

103
Q

what is treatment for endometrial hyperplasia if patient does not desiree future preg?

A

hysterectomy

104
Q

what is common bleeding sign for endometrial polyps?

A

regular menses with intermenstrual light bleeding

105
Q

what is rx for endometrial polyps?

A

hysteroscopic polypectomy

106
Q

what is uterine exam like for endometrial polyps?

A

normal usually because polyps are within the uterine cavity

107
Q

what is goal of giving combined OCP to patient with AUB who is less than 45yo?

A

estrogen will help build endometrium the progesterone will help shed it

108
Q

if a patient with AUB less than 45yo is started on OCP for control of AUB but it does not improve, what should be done? why?

A

they should have endometrial biopsy because the progesterone in the combines OCP likely isnt able to completely shed endometrium so they may be having hyperplasia

109
Q

what are some contraindications to IUD placement?

A
unexplained vaginal bleeding
pregnancy
wilson disease (copper0
liver disease (progestin)
pelvic infection
endometrial and cervical cancer
110
Q

main sx of vesicovaginal fistula?

A

continuous urinary leakage

111
Q

what are three common causes of vesicovaginal fistulas?

A

post radiation, surgery and childbirth