Week 3 study notes Flashcards

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1
Q

pros and cons of sexual reproduction?

A

pros: increased genetic variability decreased genetic disorders
cons: time and energy
low

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2
Q

pros and cons asexual reproduction?

A

cons: limited diversity
difficult to adapt
pros: only one parent
more time efficiency

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3
Q

what is fertilizations and what types of cells are required for fertilizations to occur?

A

The joining of two haploid gametes (egg and sperm) restoring the diploid condition. Haploid gametes are produced from diploid germ cells

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4
Q

Phases of Meiosis l
what order and what occurs during each phase.

A

Prophase I : “before” homologous chromosomes pair up, crossing over occurs
Prometaphase I : attachment of spindle fibers microtubules to kinetochore protein at centromere, homologous chromosomes are attached to opposite poles
Metaphase I : homologous chromosomes arrange in center of cell
Anaphase I : spindle fibers pull the linked chromosomes apart, sister chromatids remain bound at the centromere
telophase I : separated chromosomes arrive at the opposite poles
Cytokinesis : separated into two daughter cells

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5
Q

Phases of Meiosis ll what order and occurs during each during phase

A

Meiosis ll : connected sister chromatids remaining in the cells will split to form four haploids cells.
Prophase ll : chromosomes reconvenes, forming new spindles
Prometaphase II : spindles are fully formed, nuclear envelopes are completely broken down, sister chromatids form an individual kinetochore and attaches to microtubules from opposite poles
Metaphase ll : sister chromatids are aligned in the center of the cell
Anaphase ll : sister chromatids are pulled apart by spindle fibers and move towards opposite poles
telophase ll : chromosomes arrive at opposite poles and begin to decondense, nuclear envelopes form around them
Cytokinesis : separating the newly formed, unique, haploid cells

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6
Q

Know how crossing over and random, independent assortment lead to 4 gametes that each unique

A

Variety — during meiosis produce gametes with unique combinations of DNA, which results in a unique combination of genes

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7
Q

Compare/ contrast mitosis and meiosis

A

Mitosis : single nuclear division resulting two nuclei.
new cell is genetically identical to origin, contains same number of chromosomes
cells produced by mitosis function in body for growth, replacing damaged cells.

Meiosis : two nuclear divisions that results into four nuclei
new cells are never genetically identical, only one chromosome set, half of original cell
Meiosis I very different from the events of mitosis, crossover chromosomes line up as tetrads

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8
Q

Be able to explain case study of fatherless snake

A

During meiosis II did not split occur which in result a diploid egg, The diploid egg contained 2 copies of Z chromosomes

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9
Q

What is nondisjunction? When can it occur?

A

Non disjunctions when pairs of homologous chromosomes or sister chromatids fair to separate during meiosis
- Can occur during meiosis I or Meiosis II

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10
Q

What does Monosomy and Trisomy mean? identify them on a karyogram

A

Monosomy = loss of one chromosomes
Trisomy = gain of an extra chromosomes

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11
Q

discuss different human trisomies covered in class today

A

Trisomy 18 - Edwards Syndrome
Trisomy 13 - Patau Syndrome
Trisomy X - Triple X syndrome

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12
Q

What is biotechnology? How has it improved human lives

A

Artificial methods to modify the genetic material of living organisms or cells to produce new compounds or functions

Finding cures to diseases
improving crops
Insulin

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13
Q

What is genomics?

A
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14
Q

What is genetic engineering and gene therapy? what is the goal?

A

Gene therapy is a specific type of genetic engineering that may be able to cure genetic diseases someday

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15
Q

Gene editing and predicting disease rick at the individual level are two applications of genomics and what each does

A

Predicting Disease Risk at the Individual level – Screening healthy people for likelihood of developing illness/disease in the future

Gene Editing - Technology allows for more precise and direct alteration of DNA – Used to edit DNA of plants, animal, and humans, overcoming illness

example cancer cell removed

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16
Q

Structure and function of DNA and RNA

A

DNA -
Has 3 parts - deoxyribose, phosphate group, and a nitrogenous base
- Contains instructions to develop, survive and reproduce
- mRNA is made from DNA

RNA -
has 3 parts - ribose, phosphate group, nitrogenous base
- single stranded molecule (no helix)
Functions : messenger RNA (mRNA) , transfer RNA (tRNA) , ribosomal RNA (rRNA)
- Involves the production of proteins from DNA

17
Q

What is the central dogman of molecular biology

A

Staes that genetic information flows only one direction -

DNA - RNA - protein

18
Q

Understand the 3 stages of Transcription and explain what occurs during each
- know what the goal of transcription is

A

Transcriptions - DNA to RNA
- occurs in Nucleus
3 stages - Initiation, elongation, termination
Initiation - partial unwinding of DNA helix, proteins involved in transcription bind at promoter
Elongation - mRNA strand is a complement to the DNA template strand A - U , T - A , C - G , G - C
Termination - Once a gene has been transcribed, the mRNA dissociates from the DNA template, process is complete

19
Q

Understand how mRNA is coded from DNA, give appropriate mRNA strands from a template stand of DNA

A
20
Q

Understand the 3 stages of Translation and explain what occurs during each
- know what the goal of translation is

A

Translation -
protein synthesis
Initiation - ribosome assembles around the mRNA, initiates the building of the amino acid chain
elongation - ribosome shift once codon at a time , each adds an amino acid to the amino acid chain
Termination - occurs when a stop codon is encountered , polypeptide is released - will fold into its final structure