Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

HEMATOLOGY > WEEK 3 - RED BLOOD CELL MORPHOLOGY > Flashcards

WEEK 3 - RED BLOOD CELL MORPHOLOGY Flashcards

1
Q

ERYTHROCYTES

A

RED BLOOD CELL

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

MATURE RBCs SIZE

A

6.8 - 7.5 micrometers

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

AVERAGE SIZE OF MATURE RBCs

A

7.2 um diameter

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

THICKNESS OF RBC

A

1.5 - 2.5 micrometers

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

AVERAGE THICKNESS OF RBC

A

2um

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

SHAPE OF RBC

A

Round, Biconcave disc; discocyte

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

COLOR AND DIAMETER OF THE CENTRAL PALLOR OF RBC

A

Salmon Pink with central pallor
( 1/3 of the cell )

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Increased variation in the size of the RBCs

A

Anisocytosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Normal size of RBC

A

Normocytic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Smaller Size of RBC

A

MICROcytic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Larger Size of RBC

A

MACROcytic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Discocyte

A

Normocytic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

smaller than the normal size of RBC

A

MICROcytic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

associated with decreased hemoglobin
synthesis

A

MICROcytic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

MEANING OF ATIS

A

Anemia
Thalassemia
Iron deficiency anemia
Sideroblastic anemia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

larger than normal RBCs

A

MACROcytic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

resulted from a defect in either nuclear
maturation or stimulated erythropoiesis

A

MACROcytic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

disease that can be seen in
rbc size: microcytic

A

ATIS

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

disease that can be seen in
rbc size: macrocytic

A

Megaloblastic Anemia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

mature
erythrocyte that have a shape other than the its
normal shape

A

Poikilocytosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

SHAPE: lacks central pallor

A

Spherocyte

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

SHAPE: deficient in spectrin protein

A

Spherocyte

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

SHAPE: Associated with hereditary spherocytosis, G6PD

A

Spherocyte

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

SHAPE: Decreased surface volume ratio

A

Spherocyte

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
Q

SIZE: smaller, lower MCV

A

Microcytic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
26
Q

SIZE: larger, higher MCV

A

Macrocytic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
27
Q

average range of mean corpuscular volume?

A

80 - 100 fL

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
28
Q

tests that can evaluate the size variation of RBC

A
  • PBS (Peripheral blood smear)
  • RBC INDICES RESULTS: MCV, MCH, MCHC
  • RDW
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
29
Q

refers to how much surface area is available compared to the cell size

A

Decreased surface volume ratio

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
30
Q

SHAPE: known as ovalocyte

A

ELLIPTOCYTE

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
31
Q

SHAPE: caused by defects of red cell membrane
proteins

A

ELLIPTOCYTE

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
32
Q

SHAPE: appears cigar to egg shaped

A

ELLIPTOCYTE

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
33
Q

SHAPE: seen in Hereditary Elliptocytosis,
Megaloblastic anemia, Thalassemia

A

ELLIPTOCYTE

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
34
Q

SHAPE: target cells, leptocytes

A

CODOCYTE

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
35
Q

SHAPE: darkly stained at the center with light
outer rim

A

Codocyte

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
36
Q

SHAPE: surface volume to ratio is excessive;
increased

A

CODOCYTE

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
37
Q

SHAPE: crenated cell/sea urchin cell

A

Echinocyte

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
38
Q

SHAPE: has regular spicules (consistent)

A

Echinocyte

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
39
Q

SHAPE: caused by imbalance in the osmotic
pressure within the cell

A

Echinocyte

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
40
Q

SHAPE: can be seen with artificially drying
of smears or overly dried smears

A

Echinocyte

41
Q

SHAPE: sickle cell

A

DREPANOCYTE

42
Q

SHAPE: thin, elongated, pointed ends or has a
crescent shape

A

DREPANOCYTE

43
Q

SHAPE: polymerization of hemoglobin S (abnormal hemoglobin)

A

DREPANOCYTE

44
Q

SHAPE: caused by cell membrane alteration due to
amino acid substitution

A

DREPANOCYTE

45
Q

SHAPE: prone to low oxygen levels and
decreased blood pH because these are
non-functional RBCs

A

DREPANOCYTE

46
Q

SHAPE: fragmented RBC with pointed projections
(due to ruptures)

A

SCHISTOCYTE

47
Q

SHAPE: can be seen in MAHA (microangiopathic hemolytic anemia), Uremia, DIC
(disseminated intravascular coagulation)

A

SCHISTOCYTE

48
Q

SHAPE: Teardrop cell/pear-shaped with one blunt projection

A

DACRYOCYTE

49
Q

SHAPE: mouth cell

A

Stomatocyte

50
Q

SHAPE: slit-like central pallor

A

Stomatocyte

51
Q

caused by osmotic changes due to cation
imbalance (Na+, K+)

A

Stomatocyte

52
Q

Two types of Hereditary Stomatocytosis

A

Overhydrated, Dehydrated

53
Q

What is Overhydrated Hereditary Stomatocytosis ?

A

increased Na+ inside the
cell

54
Q

What is Dehydrated Hereditary Stomatocytosis?

A

decreased intracellular K+
- associated with Rh null (patients without
Rh antigen), Alcoholism, Severe liver
disease

55
Q

SHAPE: thorny cells/spur cells

A

ACANTHOCYTE

56
Q

SHAPE: irregular spicules (opposed to echinocytes)

A

ACANTHOCYTE

57
Q

Shape: caused by excessive cholesterol in the
membrane

A

ACANTHOCYTE

58
Q

Normal RBC appearance

A

pinkish red with a lighter-colored when stained

59
Q

What is the color in the middle of the RBC?

A

hemoglobin present in the cell

60
Q

BIGGER central pallor: _______ hemoglobin content

A

LOWER

61
Q

SMALLER central pallor: _________ hemoglobin content

A

HIGHER

62
Q

________ central pallor: HIGHER hemoglobin content

A

SMALLER

63
Q

_______ central pallor: LOWER hemoglobin content

A

BIGGER

64
Q

term for a variation
in the normal coloration of RBCs

A

ANISOCHROMIA

65
Q

Normal hemoglobin content

A

Normochromasia

66
Q

Low hemoglobin content

A

Hypochromasia

67
Q

High hemoglobin content

A

Hyperchromasia

68
Q

HEMOGLOBIN CONTENT: RBC contains residuals of RNA,
somehow immature; reticulocytosis

A

Blue-colored: polychromasia

69
Q

HEMOGLOBIN CONTENT: Central pallor exceeds 1/3 of the cell
diameter

A

Hypochromia

70
Q

HEMOGLOBIN CONTENT: Associated with Iron deficiency anemia,
Thalassemia, Sideroblastic anemia

A

Hypochromia

71
Q

HEMOGLOBIN CONTENT: Low MCH, MCHC, and decreased red cell
size, low hemoglobin

A

Hypochromia

72
Q

HEMOGLOBIN CONTENT: A condition wherein the red cells are
deeply stained to abnormal thickness of
cells

A

Hyperchromia

73
Q

INCLUSION BODIES: red cells have fine to coarse granular
inclusion bodies evenly dispersed
throughout the cell

A

BASOPHILIC STIPPLING

74
Q

INCLUSION BODIES: visualized by Wright stain and Supravital
stain (dark blue)

A
  • BASOPHILIC STIPPLING
  • Cabot Rings
  • Howell Jolly Bodies
75
Q

INCLUSION BODIES: blueberry-bagel appearance

A

BASOPHILIC STIPPLING

76
Q

INCLUSION BODIES: appear as figure of eight, ringed shape,
loop shaped

A

cabot rings

77
Q

INCLUSION BODIES: probably microtubules remaining from
mitosis (spindle remnants)

A

Cabot Rings

78
Q

INCLUSION BODIES: abnormal histone biosynthesis

A

Cabot Rings

79
Q

INCLUSION BODIES: represent denatured and precipitated
hemoglobin

A

HEINZ BODIES

80
Q

INCLUSION BODIES: must use supravital stain to visualize

A

HEINZ BODIES

81
Q

INCLUSION BODIES: pitted golf ball appearance

A

HEINZ BODIES

82
Q

INCLUSION BODIES: irregular granules (opposed to solid
granules of Howell Jolly bodies)

A

HEINZ BODIES

83
Q

INCLUSION BODIES: they are nuclear remnants predominantly
compared of Heinz bodies

A

Howell Jolly Bodies

84
Q

INCLUSION BODIES: round, solid staining, dark-blue to purple
inclusion with Wright/Supravital stain

A

Howell Jolly Bodies

85
Q

INCLUSION BODIES: due to overstimulation of erythropoiesis

A

Howell Jolly Bodies

86
Q

INCLUSION BODIES: remnants predominantly composed
of DNA

A

Howell Jolly Bodies

87
Q

INCLUSION BODIES: siderotic granules

A

Pappenheimer Bodies

88
Q

INCLUSION BODIES: dark-stained particles of iron, visualized by means of Prussia blue (iron
stain)

A

Pappenheimer Bodies

89
Q

INCLUSION BODIES: aggregates of iron, mitochondria, and
ribosomes

A

Pappenheimer Bodies

90
Q

INCLUSION BODIES: Appear as rod-shaped, angular opaque
structure within some RBCs

A

Hb C Crystals

91
Q

INCLUSION BODIES: Precipitated bodies of polymers of beta
chain of Hb A

A

Hb H bodies

92
Q

ALTERATION: stacked RBCs

A

Rouleaux formation

93
Q

ALTERATION: even if washed
with saline and it keeps it’s stacked
formations

A

Rouleaux formation

94
Q

ALTERATION: associated with high protein levels

A

Rouleaux formation

95
Q

ALTERATION: pseudo rouleaux formation can be washed with?

A

NSS

96
Q

ALTERATION: It can be washed with NSS

A

pseudo rouleaux

97
Q

ALTERATION: no pattern of RBC clumping

A

Agglutination

98
Q

ALTERATION: due to reaction of red cells when coated
with antibodies

A

Agglutination

99
Q

MCV meaning

A

Mean Corpuscular Volume

HEMATOLOGY (4 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions