WEEK 3 - Neuropathy Flashcards

Carpal tunnel, Radiculopathy, Diabetic Neuropathy

1
Q

What is the most common peripheral neuropathy?

A

diabetic neuropathy

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2
Q

what is the most inherited peripheral neuropathy?

A

Charcot-Marie-Tooth Disease

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3
Q

there are 90 known causes of neuropathy true or false?

A

false

<100

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4
Q

______ refers to “pinching” or “irritation” of a spinal nerve root.

A

radiculopathy

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5
Q

what are the most frequently impacted cervical radiculopathies?

A

C6 spinal nerve root
C7 spinal nerve root
C8 spinal nerve root

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6
Q

what are the most frequently impacted Lumbar radiculopathies?

A

L4 spinal nerve root
L5 spinal nerve root
S1 spinal nerve root

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7
Q

________ may be caused by radiculopathy involving any of the following nerve roots (L4,L5,S1,S2)

A

Sciatica

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8
Q

what are the causes of radiculopathy

A

narrowing of vertebral bodies:

  1. spinal stenosis;
    • from DDD
    • Bone spurs
    • Osteophytes
  2. Disc Bulge/ Herniation
    from:
    - inner fluid
    - disc bulge
    - herniation irritates
    nerve root
  3. Spondylolisthesis
    - slipping of top vertebrae forward on lower vertebrea

Retrolisthesis:
- slipping of top vertebrea posteriorly onto lower vertebrea

  1. tumour

-

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9
Q

what are some symptoms of radiculopathy?

A
  • pain often radiating through limb
  • paresthesia (pins/needles)
  • numbness
  • weakness or heaviness
  • muscle spasm
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10
Q

how do u asses for radiculopathy?

A

clinical:
- dermatomal
- myotome weakness
- hyporeflexia or areflexia

neuroimaging
- X-Ray, CT, MRI

Nerve conduction test + EMG

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11
Q

what are the treatments for radiculopathy?

A

modalities:
- TENS
- Acupuncture
- heat
- massage

Physiotherapy/ chiro
- traction
- joint manipulation (MOBS)

Exercises:
- posture correction
- stretching
- muscle imbalance correction
- improved movement mechanics

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12
Q

what are some medications for radiculopathy?

A
  • NSAIDS
  • Neuropathic pain (Gabapentin, SSRIs)
  • epidural steroid injections
  • selective nerve blocks
  • muscle relaxants for muscle spasms
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13
Q

what is treatment for radiculopathy?

A

decompression surgery

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14
Q

what are the types of decompression surgery ?

A

disectomy + fusion (remove entire disc, put implant in and bone’s fuse together
microdisectomy (make tiny cut in back of spinal and only remove damaged disc)
foraminoplasty
fusion/fixation

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15
Q

carpal tunnel syndrom is due to _____ ________ inflammation

not talking about median nerve

A

flexor tendon inflammation

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16
Q

what is the lifetime risk for carpal tunnel?

more common in what gender

does > age mean > risk?

A

~10%

woman

yes

17
Q

what spinal nerve roots enter the carpal tunnel?

18
Q

What are some carpal tunnel risk factors?

A
  • family history
  • trauma
  • pregnancy
  • stress
  • other diseases (RA or Hypothyrodism)
19
Q

what are the sensory symptoms of carpal tunnel syndrome?

A
  • parasthesia: numbness + pain along median nerve
  • severe pain at night
    • burning, aching, numbness & tingling
20
Q

where does the median nerve supply what digit’s?

A

palm side of

thumb, index, middle, & half of ring finger

*can be unilateral or bilateral

21
Q

what are some motor symptoms of carpal tunnel syndrome?

A

muscle weakness

hand stiffness + clumsiness

observable Thenar eminence atrophy

22
Q

the median nerve primarily supplies _______ muscles

A

thenar muscles

23
Q

how to diagnose carpal Tunnel syndrome

A

EMG, nerve conduction velocity

US

MRI (looking for compression)

24
Q

what are sensory tests for testing carpal tunnel syndrome

A

tinel’s test:
- tapping of hand + forearm over median nerve

positive: if felt
- tingling
- numbness
- shock

phalens test:
- holding arms out + flexing wrists for min

positive if:
- tingling
- numbness
- pain

25
what is the treatment for carpal tunnel syndrome
- rest - night brace - modified activity to dec inflammation + stress - physio (US, Massage, acu) - cortisone shots - carpal tunnel surgery (last resort) - open - endoscopic
26
_____ - _______ of all diabetics have some degree of
60-70%
27
what are the sensory symptoms of diabetic neuropathy?
1. paresthesia (numbness, tingling of extremities) 2. dysesthesia: sense is distorted - primarily touch ( normal touch may be felt as burning, pins & needles, electric shock) 3. loss of proprioception - where ur limb is in space 4. glove-stocking distribution
28
true or false for diabetic neuropathy affects longer neurons more severely
true + symptoms appear fist in the toes
29
______ = the symmetrical sensory loss in hands and feet
glove-stocking distribution
30
what are the motor symptoms of diabetic neuropathy?
1. weakness - poor fine motor coordination - dropped foot, foot slapping, toe cuffing 2. Dysphagia: difficulty swallowing 3. fasciculations: small, local muscle twitch
31
true or false motor symptoms diabetic neuropathy come first?
false sensory do and motor occur later in progression
32
the key are characteristics of what? 1. hip step foot during gait 2. unable to dorsiflex foot
diabetic neuropathy GAIT
33
true or false diabetic neuropathy leads to sensory, motor, and autonomic symptoms
true
34
what are some examples of autonomic symptoms
digestive symptoms: - bloating - heartburn - nausea - vomiting diarrhea or constipation blood vessels: - orthostatic hypotension w/ dizziness - Low blood pressure - increased HR
35
the most common autonomic symptoms for diabetic neuropathy is often in?
- digestive system - blood vessels - urinary system - sexual dysfunction
36
what does hyperglycemia do to neurons?
directly damages neurons via pathways resulting in oxidative stress indirectly damages neurons through decreased elasticity + damage to blood vessels + peripheral perfusion (blood flow to extremeties)
37
how does diabetic neuropathy affect blood vessels
vasoconstriction hypoxia/ ischemia nerve damage / demyelination
38
how do you assess for diabetic neuropathy?
SENSORY: - microfilament testing - vibration testing - nerve conduction velocity testing
39
how to treat diabetic neuropathy?
1. Glycemic control; metformin, insulin, exercise, nutrition 2. neuropathic pain meds - NSAIDS - GABAPENTIN - antidepressant SSRI's