Week 3: Antenatal Development and Birth Flashcards
What are the three stages of conception?
1 - Zygote. As the zygote moves down the fallopian tube it duplicates, at first slowly and then more rapidly
2- Blastocyst. By the fourth day it forms a hallow fluid-filled ball, called a blastocyst. The inner cells, called the embryonic disk will become the new organism. The outer cells, or trophoblast will provide protective covering
3- Implantation. At the end of the first week the blastocyst begins to implant in uterine lining
What is the embryonic disk ?
Inner cells of the blastocyst
part that becomes the organism
What is the trophoblast?
Outer cells of the blastocyst providing protective covering
Antenatal stages names (3 stages)
- The period of the zygote or The germinal period
- The period of the embryo or The embryonic period
- The period of the fetus or The fetal period
Period of zygote/ geminal period
- 2 weeks (30% of zygotes don’t last this)
-Beings with fertilisation in the upper end of the fallopian tube ends when the blastocyst invades the uterine wall and implants in it
-series of cell division occurs, 36 hours - 2 cells, 48 hours - 4 cells.
-3 days = small compact ball of 16-32 cells called blastocyte
Fertilisation
sperm penetrates the ovum (most sperm never reach the fallopian tube in order to be able to fertilise the ova) After one sperm does penetrate the surface changes no other sperm can penetrate.
Embryonic period key structures
Placenta – Provides oxygen and nutrients; removes waste
Yolk Sac – Produces early blood cells before the liver takes over
Amniotic Fluid – Cushions and protects the embryo
Chorion – Forms the outer membrane and helps develop the placenta
Umbilical Cord – Connects embryo to placenta; delivers nutrients and oxygen
Amnion – Inner membrane filled with amniotic fluid for protection
Ectoderm
-becomes hair, nails, skin and nervous system
Mesoderm
-Becomes circulatory system, lungs (epithelial layers) , skeletal system, muscular systems
Endoderm
-Becomes the digestive system, liver, pancreas, lungs (inner layers)
Embryonic Period processes/ timeframe
-3 weeks to 8 weeks (i.e. end of 2nd Month)
-Rapid growth: eyes, ears, nose, jaw, and neck form
- Buds become arms, legs, fingers, and toes
- At 7 weeks, the production of neurons (nerve cells) begins
-By the end of the 2nd month the embryo can sense its world and move
Dating pregnancies
-Most countries count from first day of last period (including NZ)
-Other countries do the actual conception date
Fetal period
From 9th week to end of pregnancy
-spans all three trimesters (1st , 2nd, 3rd) which are typically talked about
-Rapidly increases in size and and development
1st trimester
1-12 weeks
-By 12 weeks organ muscles and nervous system becomes organised form (genital)
-heartbeat
Second Trimester
13-24 weeks
-By middle of second trimester the baby to feel movements of baby, vernix develops to prevent chafing of embryonic fluid against skin (sticky white grease ), laungo develops (white downy hair to allow vernix to stick).
-By end of second trimester many organs including the brain are developed, glial cell levels increase rapidly
-Age of viability (i.e. could survive if born) is 22-26 weeks but continues to decrease as technology advances
Third Trimester
-25-38 weeks
-Age of viability reached at 22-26 weeks
-Cerebral cortex enlarges
-Fetus spends more time awake
-Gains 2kg and gros approx 18 cm
-Personality begins to be present
-Assume upside-down position to prepare for birth in final weeks
Teratogen
Any environmental agent that causes damage during the antenatal
period.
* E.g. Prescription and non-prescription drugs, illegal drugs, alcohol, and
tobacco i.e. things that pass through the placenta blood flow to the baby from the mum
The harm teratogens do is shaped by:
- Dose and duration (small doses of the substance might be fine)
- Heredity or genetic makeup (i.e. the baby might be more sensitive to it like an allergy + might be the mum’s genetic makeup i.e. they might be more resistant to the teratogen)
- Other negative influences
- Time of exposure → A sensitive period (a particular period during babies development which has more of an impact than other times)
Sensitive period + what theory of development is it associated with?
-A period where a behaviour or part of the body is biological prepared to develop rapidly and particularly sensitive to it’s surrounds
-associated with ethology theoretical approach
-There are various sensitive periods throughout the antenatal period e.g. nervous system all the way from 3 weeks to full term 20 weeks whereas teeth has smaller sensitive period from 6 to 8 weeks
Teratogens: Prescription Drugs and pregnancy
-Metsafe has a lot of information about the risks associated with certain drugs
-Should be used with caution and only be prescribed if benefits outweigh risks
Infectious Diseases & Pregnancy
-Chicken pox : not known to cause miscarriage but can cause physical malformations, intellectual disability, low birth weight and prematurity.
-> suggest have a shot if haven’t had in childhood
-Rubella : cause miscarriage, physical malformations, intellectual disability and low birth weight. Most common side effect of rubella in pregnancy is deafness.
-> strongly suggested to get the MMR vaccine
-Syphilis (STD): devasting effects on fetus causing miscarriage, physical malformations, intellectual disability, low birthweight
3 stages of labour
-Stage 1 = 6 and 36 hours for first time mum. Longest period involves the dilation (opening) and effacement (thinning) of cervix. Contractions progressive get more intense. Transition is the term used when intensity + frequency of contractions are at most, women might vomit, feel overwhelmed / distressed and cervix is open completely.Complete dilation of cervix is 10 cm.
-Stage 2 = pushing the head emerges (hardest part) and then the neck and shoulders follow reasonably quick resulting in the birth of the baby
=Stage 3= Delivery of the placenta with a few pushes. Usually umbilical cord is cut immediately after birth and before placenta birth but others leave the placenta attached and research shows that the placenta blood can continue to nourish the baby (good for vulnerable, premature babies). Maori have been doing this technique for years but has been hailed as ‘new’ within the wester world.
The Apgar scale: A assessment of newborn’s physical condition
- An assessment that takes place twice
At 1 minute after birth
At 5 minutes after birth - Baby is assessed & rated as either 0, 1, or
2 on each of the following 5 characteristics …
Appearance (skin color) 0 blue -> 2 pink and tinged (i.e. good)
Pulse (heart rate)
Grimace response (reflexes)
Activity (muscle tone)
Respiration (breathing rate and effort)
- A score of 7+ → good physical condition
- A score of 4–6 → assistance required in
establishing breathing and other vital signs - A score of less than 3→ emergency medical
attention required
Usually Apgar goes up from 1 min to 5 mins
What are the three primary germ layers in early embryonic development?
ectoderm, mesoderm, and endoderm
Each layer gives rise to specific tissues and organs in the body