WEEK 3 Flashcards

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1
Q

what do betablockers do?

A

block catecholamines (NE & E)

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2
Q

what are the two arms of the immune system?

A
  1. INNATE: fast acting, nonspecific
    - monocytes (macrophages): engulf/digest and signal other immune cells
  2. ADAPTIVE: specific, slow acting
    - T-cells + B-cells that protect against pathogens
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3
Q

what triggers inflammation and what is it designed to do?

A
  • triggered by “danger signals” released by macrophages (cytokines);
  • designed to bring immune cells into damaged area
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4
Q

CD4 T cells:

A

helper cells that direct other immune cells to attack

pathogens

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5
Q

CD8 T cells:

A

find infected cells and kill them

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6
Q

___ attack INSIDE of the cell while ___ attack from the OUTSIDE

A

T-cells; B-cells

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7
Q

during ____ stress, T and B cells are suppressed.

A

chronic

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8
Q

during ____ stress, parts of the immune system are enhanced.

A

actute

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9
Q

what types of stressors are associated with greater risk of developing a cold?

A
  • interpersonal problems with family and
    friends
  • work-related stressors
    lasting at least one month
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10
Q

HIV infects and kills ___ cells

A

CD4 T cells

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11
Q

animal research on stress and HIV demonstrated that:

A

social stressors –> quicker death

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12
Q

what is the Y in HIV and stress?

A

reduced anti-viral immune response

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13
Q

NE + HIV cells = ?

A

higher viral load

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14
Q

results of nonprimate research on stress and HIV:

A

stress increases viral replication; effects mediated by NE increase

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15
Q

what was the intervention in Antoni’s study?

A

CBSM: group based intervention + stress appraisal, coping skills, social support

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16
Q

HIV leads to elevated _____ activity + reduced ____

A

sympathetic nervous system; CD4T cels

17
Q

what type of control group was used in Antoni?

A

wait list

18
Q

in Antoni’s study, anxiety was mediated by _____

A

NE and CD8 count

19
Q

what did the Antoni study find?

A

improved psychosocial effects (reduced anxiety, depression, distress, improved QOL) but not biological

20
Q

what’s the X–>Y–>Z in Antoni’s study?

A

X: stress management
Y: decreases in NE
Y: increases in CD8 T cells
Z: disease