week 3 Flashcards
define life expectancy
average number of years individuals in a particular birth cohort can be expected to live on the basis of current information that affects mortality
define life span
maximum longevity, or extreme upper limit of time, members of a species can live. As life expectancy approaches life span, the survival curve takes on a more rectangular shape
define morbidity and mortality
illness and disease, and mortality refers to death.
these two terms are related, but they are not the same.
describe the trends seen in human life expectancy and human life span
human life expectancy has been increasing, but human life span has changed very little over time
what is the life expectancy for Canada in 2023? what was the increase from 2022? 2021?
82.96 years
0.18% increase from 2022. that was a 0.18% increase from 2021.
differentiate between primary and secondary aging
Primary aging refers to unavoidable (inevitable), intrinsic biological processes that affect all members of a species.
Secondary aging refers to biological processes due to disease, disuse, and abuse.
what are the types of biological theories of aging? briefly describe
Programmed theories focus on genetic blueprints of various species.
Stochastic theories focus on random events and damage that occur as a function of living.
differentiate between ADL and IADL
Activities of daily living (ADL) include basic personal care tasks required for self-maintenance
instrumental activities of daily living (IADL) include more complex activities required for carrying out the business of daily life.
Limitations in either or both occur more frequently in the 85+ age group.
what are some unique features of the nun study?
multiple evaluations over many years
extensive data from early life
homogeneity in living conditions, working conditions, lifestyle
brain donation is a requirement
follow up easy - live in congregation
single cohort - 75 yrs old +
what could be used to predict the presence of alzheimers?
those with higher brain and volume had lower chance of alzheimers.
bigger predictor is the vascular effect
low linguistic ability in early life
differentiate between compression of morbidity and mortality
compression of morbidity: illness or extreme disability will occur only during a narrow period of time immediately prior to death
compression of mortality: where a greater proportion of deaths will occur during a very narrow time period toward the upper limit of the human life span. can be shown with rectangular survival curve
what are the programmed theories of biological aging? describe them
time clock theory (cellular aging): suggests that the life span is controlled by a genetically determined time clock operating at the cellular level - inferred from the amount of cell division a cell undergoes
immune theory: immune system is programmed to maintain efficiency for a certain amount of time, after which it starts to decline
evolutionary theory: members of a species are genetically programmed to bear and rear their young. once they reproduce and raise their offspring to independence, they fulfilled their service in perpetuating the species.
what are the stochastic theories of biological aging? describe them
error theory: errors occur at the cellular level from the organism’s metabolic processes or exposure to environmental factors such as radiation
wear and tear theory (rate of living theory): begins life with a fixed amount of physiological energy. if expended quickly, aging begins early and proceeds rapidly
stress theory: biological system sustains damage from prolonged exposure to stress
cross-linking theory: cross-linking affects metabolic functioning because it obstructs the passage of nutrients and waste products into and out of cells
free radical theory: focuses on unstable molecular fragments (free radicals), which are formed as a byproduct of the body’s normal metabolic processes. because of their instability, free radicals unite with molecules that happen their way, thereby preventing those molecules from functioning normally
describe how nature affects the life expectancy?? of an individual
most people who live beyond age 70 have at least one parent or grandparent who lived into the 70s. the age of the mother’s death seems to be a better predictor of a person’s longevity
differentiate between osteoarthritis and osteoporosis
Osteoarthritis (OA) is the most common form of degenerative joint disease, and risk factors include increasing age, obesity, heredity, low socioeconomic status, and female gender.
Osteoporosis is a skeletal disease characterized by extreme loss of bone mass and deterioration of bone tissue, resulting in bone fragility and susceptibility to fracture.