Week 2 - Types of Research

Question 1

Randomization in randomized clinical trials allows researchers to _______

Answer 1

ensure that the observed outcomes are due to treatment

Question 2

Concealed allocation prevents anyone from anticipating ____________

Answer 2

which group patients will be assigned to.

Question 3

List drawbacks about randomized clinical trials.

Answer 3

• In some instances it is impractical or unethical to randomly assign patients to an exposure.
• The results of RCTs are difficult to generalize to patients in clinical practice
• They usually take a long time to complete

Question 4

List strengths of randomized clinical trials.

Answer 4

They use methods that minimize bias

Question 5

Basic science research often measures what type of outcomes?

Answer 5

Disease-oriented measures, such as cell counts, cell changes, or biochemical markers

Question 6

Basic science research provides ________

Answer 6

• New findings about genetic and environmental factors
• Information leading to new tests that can detect illness
• Explanations for how treatments already in use may work

Question 7

What is a limitation of basic science research?

Answer 7

It cannot be immediately applied to patients.

Question 8

When biochemical, tissue, and animal data point to a mechanism of action or demonstrate the desired biological effect, this is known as ______

Answer 8

Biological plausibility