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Anesthesia pharmacology > Week 2 opiods > Flashcards

Week 2 opiods Flashcards

1
Q

Morphine intrathecal dosing (adult and peds)

A

adults 0.1-0.5mg
peds 0.01mg/kg

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2
Q

Morphine epidural (bolus, infusing, and peds)

A

Bolus: 2-6 mg q8-24h
Infusing: 0.2-1mg/hr
Peds: 0.03-0.05mg/kg (MAX:0.1mg/kg or 5mg/24hrs)

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3
Q

Hydromorphone (dilaudid) analgesia dose (adult and peds)

A

Adult: 0.4-2mg IV
Peds: 0.005-0.02mg/kg

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4
Q

Hydromorphone PCA dose (adult and peds demand and basal)

A

Adult demand: 0.2-0.6mg q5-15min
Adult basal: 0-0.2mg/hr
Peds demand: 0.005-0.02mg/kg q6-20mins
Peds basal: 0-0.005mg/kg/hr

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5
Q

Meperidine sedation/analgesia (adult, peds, post op shivering)

A

Adult: 50-150mg IV, IM q3-4h
Peds: 0.5-2mg/kg IV, IM
Adult post op shivering: 12.5-25mg IV

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6
Q

Fentanyl intubation adjunct

A

1-3mcg/kg

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7
Q

Fentanyl sedation/analgesia(load and maint)

A

0.5mcg/kg(load); 0.01-0.04mcg/kg/hr(maint)

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8
Q

Fent GA adjunct(bolus and infusion)

A

2-20mcg/kg bolus; 2-10mcg/kg/hr infusion

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9
Q

Fent high dose

A

20-50mcg/kg

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10
Q

Fent cardiac surgery

A

up to 150mcg/kg as sole GA agent

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11
Q

Fent postop

A

0.5-1.5mcg/kg

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12
Q

Fent Intrathecal

A

10-25mcg

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13
Q

Fent epidural

A

10-100mcg, or mixed in local anesthetic 2-10mcg/ml

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14
Q

Fent PCA

A

10-20mcg q6-20min

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15
Q

Remifentanil induction dose

A

1-3mcg/kg over 1 min

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16
Q

Remifentanil GA adjunct(loading, bolus, maintenance)

A

Loading:0.5-2mcg/kg
Bolus:0.5-1mcg/kg
Maintenance:0.05-2mcg/kg/min

17
Q

Remifentanil sedation(load and maintenance)
Propofol warning*

A

Load: over 30-60seconds 0.5-1mcg/kg
Maintenance 0.025-0.2mcg/kg/min
* increased respiratory depression with propofol*

18
Q

Sufentanil GA(minor procedure)

A

1-2mcg/kg load then 10-50 mcg PRN

19
Q

Sufentanil GA (moderate procedure)

A

2-8mcg/kg load then 10-50mcg PRN, infusion 0.3-1.5mcg/kg/hr

20
Q

Sufentanil GA (major procedure)

A

8-30mcg/kg load then 10-50mcg PRN, infusion 0.5-2.5 mcg/kg/hr

21
Q

Sufentanil sedation (load and infusion)

A

Load: 0.1-0.5mcg/kg
Infusion: 0.005-0.01 mcg/kg/min

22
Q

Sufentanil epidural

A

10-15 mcg/10ml of 0.125 bupivacaine

23
Q

Methadone (PO, IV/IM/SC)

A

Adult: 2.5-10 MG PO
IV/IM/SC 2.5mg-5mg q8-12hrs
*titrate up q3-5 days

24
Q

Oxycodone(immediate and controlled release)

A

Adult IR- 5-15mg PO q4-6hrs
Adult ER- 10mg q8-q12
Titrate by 25-50% q1-2 days

25
Q

Hydrocodone

A

2.5-10mg q4hrs

*Morphine 10mg=hydrocodone 5-10mg

26
Q

Codeine (antitussive and pain-adult and peds)

A

Antitussive: 15mg
Pain adult:15-60mg PO q4-6h (max 120mg/d)
peds pain- 1-1.5mg/kg/day divided by q4-6hr
Age 2-6: 30mg/day max
Age 6-12: 60mg/day max

27
Q

Buprenorphine (IV/IM)

A

0.3-0.4mg q6-8h (may repeat initial dose in 30-60mins x1)
*Doses greater than 0.3mg/dose should ONLY be given IM

28
Q

Buprenorphine 2-12 years old

A

2-6mcg/kg IV/IM q4-6h (max 6mcg/kg/dose)

29
Q

Buprenorphine>13years old

A

0.3mg IV/IM q6-8h (max 300 mcg/dose)

30
Q

Buprenorphine epidural

A

0.3mg

31
Q

Buprenorphine intrathecal

A

0.15mg

32
Q

Naloxone (opiate OD)

A

0.2-0.4mg IV q2-3min PRN(MAX 10 10mg) then may infuse at 0.4mg/hr and titrate to effect

33
Q

Naloxone (reversal of opiate resp depression)

A

0.04-0.4mg doses IV titrated q2-3min

Infusion load of 5 mcg/kg followed by 2.5-160 mcg/kg/hr

34
Q

Naloxone reversal of opiate-induced pruritis

A

0.25 mcg/kg/hr

35
Q

Naloxone birth-5years or less than 20 kg

A

0.1mg/kg IV q2-3min PRN

36
Q

Naloxone >5yrs or greater than 20 kg (opiod OD)

A

2mg/dose q2-3 PRN, infusion 0.4mg/hr and titrate to effect (same as adult)

37
Q

Naloxone >5yrs or greater than 20kg (reversal of opiate resp depression)

A

1-10mcg/kg IV titrated q2-3min up to 0.4mg

38
Q

Naloxone >5yrs or greater than 20kg (treatment of opiate-induced pruritis)

A

0.25mcg/kg/hr

Anesthesia pharmacology (2 decks)

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