Week 2 module 2 Flashcards
What is the normal physiology of cognitive changes?
Loss of synaptic connections
• Creates memory impairment (slowed but intact)
• Evidence of mild decline in executive functioning
What is the pathological physiology of cognitive changes?
- Certain growth factors in brain are inhibited
- Death and loss of neurons
- Dementia
What is the continuum of cognitive changes?
Normal Aging –> Mild Impairment –> Dementia
Not everyone follows the continuum
What are the most common types of dementia?
- Alzheimer’s Disease
- Vascular
- Lewy Body
What does dementia commonly affect?
Commonly affect memory and language
What are the other cognitive deficits seen with dementia?
- Aphasia
- Apraxia
- Disturbance of executive function
___ is the most common form of dementia
Alzheimer’s Disease is the most common form of dementia
What are the characteristics of Alzheimer’s Disease?
- Early onset (30-60 years of age)
* Late onset
What are the risk factors for Alzheimer’s Disease?
- Advancing age
- Positive family history
- Women > Men
- > African American and Hispanic populations
What are the clinical presentation for Alzheimer’s Disease?
- Memory impairment
- Lapse in judgment
- Personality changes
- Depression possible
- Language problems
- Difficulty with ADLs
- Visual spatial problems
- Short tempered, hostile
- Loss of motor function (swallowing, bowel/bladder)
___ is the second most common type of dementia
Vascular Dementia is the second most common type of dementia
What are the risk factors for Vascular Dementia?
- HTN
- Smoking
- Hypercholesteremia
- Diabetes mellitus
- Cardiovascular disease
- Cerebrovascular disease
What are the clinical presentation for Vascular Dementia?
• Memory
• Abstract thinking
• Judgement
• Impulse control
• Personality changes
• Characterized more by abrupt onset, step by step
deterioration, fluctuating course, and emotional lability
What is lewy body dementia?
Progressive cognitive decline with 1. Fluctuations in alertness and attention • May be drowsy or lethargic 2. Visual hallucinations 3. Parkinsonian motor symptoms
What are the clinical presentation for lewy body dementia?
- Gait and balance issues
- Visual spatial issues
- Poor executive functioning
- Sensitivity to antipsychotics
- May be depressed
What is delirium?
Sudden, rapid change in mental function
• Often confused with Dementia
• Usually short term, temporary
What is delirium associated?
- Medical illness
- Recovery from surgery
- Hospital admission
What are the clinical presentation for delirium?
- Shouting and resisting
- Refusal to cooperate with medical care
- Potential to be injured falling
- Combative
- Pulling of lines and tubes
What does the treatment of delirium focus on?
- Increased time OOB
- Walking
- Managing hydration
- Hypoxia
- Nutrition
What is a major depressive episode?
Depressed mood or loss of pleasure in all activities
AND at least 5 associated symptoms for at least 2 weeks that impact function, social, or occupational endeavors
What are the associated symptoms of major depressive episode?
- Weight loss
- Insomnia
- Hypersomnia
- Decreased or hyperactive motor activity
- Fatigue
- Loss of energy
- Feelings of worthlessness
- Excessive inappropriate
guilt - Diminished ability to think or concentrate
- Recurrent thoughts of death
- Suicide ideation or attempt
What is an adjustment disorder with depressed mood?
Maladaptive reactions to identifiable psychosocial
stressors that occur within 3 months of onset of stressors
What does adjustment disorder with depressed mood do?
Impairs social or occupational function or marked
distressed in excess of normal or expected reaction.
What are the symptoms of adjustment disorder with depressed mood?
- Depressed mood
- Tearfulness
- Feelings of hopelessness
What are the characteristics of the Two Question Depression Test?
• “Over the past two weeks, have you ever felt down,
depressed, or hopeless?”
• “Have you felt little interest or pleasure in doing things?”
An answer of yes to these two questions indicates a need for referral or follow up with MD
What are the characteristics of the Geriatric Depression Scale?
30 questions, yes (1 point), no (0 point)
• Score greater than 10, need referral or follow up
• 0-9 normal, 10-19 mild depressive, 20-30 severe depressive
What are the characteristics of the Center for Epidemiological Studies Depression Scale (CES-D)?
- 20 questions
- Likert scale questions > 16 points may need referral
- The higher the number the more likely depression is an issue
Why is addressing depression in the aging population important?
• Suicide is more prevalent in the aging population (16%) than in the teenage population (14%)
• Highest suicide rates are in the greater than 65 year of age
group
• Aging adults may have been born and raised to feel that mental illness is stigmatized and emotions should not be emphasized, making them less likely to talk about it or seek help
What are the physical illness that aging adults may face that can increase the risk of depression?
- Restricted mobility
- Assistance with self care
- Dependency
- Feeling burdensome
What are the characteristics of depression and the older adult?
- Depression can lead to further reduction in functional capacity
- Depression can increase the risk of developing new illnesses
What are the different ways of managing depression?
- Pharmacotherapy (SSRIs, TCAs, etc.)
- Psychotherapy
- Exercise and Physical Activity
What are the characteristics of pharmacotherapy as a method of managing depression?
Be aware that patient on Tricyclic or Tetracyclic Antidepressants (Amitril, Elavil, Aventyl, Pamelor), may experience hypotensive side effects.
What are the characteristics of psychotherapy as a method of managing depression?
Aging adults are less likely to seek this option, and health
professionals also often demonstrate ageism with these patients
What are the characteristics of exercise and physical activity as a method of managing depression?
- Reduces depressive symptoms
* Improves function
What are the characteristics of PT with the depressed aging adult?
• Timeline may need to be longer to accomplish goals
• May need to focus on ADL training as these tasks require more energy and may be more difficult for the patient
• Matter of fact approach is better than overly cheerful approach
• Discourage negative self perception and emphasize
achievement
• Demonstrate a genuine and respectful regard for the patient
• Realize, these patients aren’t “fun” at times because they
appear unmotivated, but they aren’t lazy. It just takes a lot of
energy to accomplish simple tasks
Many CVP changes common in aging adults are due to _____
Many CVP changes common in aging adults are due to modifiable factors, not necessarily aging!
What does aging do to the cardiopulmonary and cardiovascular system?
Aging changes the resiliency of the system to adapt to previously silent abnormalities/latent disease or respond to system insults
___ is a major cause of death in > 65
Cardiovascular disease is a major cause of death in > 65
What are the morphological and structural changes that happens to the thorax due to normal aging?
• Calcification of bronchial and costal cartilage
• ↑stiffness of costovertebral joints
• ↑anteroposterior diameter
• ↑wasting of respiratory muscles (diaphragm and
intercostals)
• Structural changes in thoracic cage and spine
What is the functional significance of the morphological and structural changes that happens to the thorax due to normal aging?
- ↑resistance to chest wall deformation
- ↓forced expiratory volume (FEV1)
- ↓forced vital capacity (FVC)
- ↓cough force
- ↑aspiration or choking risk
What are the morphological and structural changes that happens to the lungs due to normal aging?
- ↑size alveolar ducts/↑alveoli size
- ↑alveolar compliance
- ↑mucous glands/↓mucous clearance
- ↑stiffness of pulmonary vasculature
- ↓bronchial smooth muscle integrity
- ↓lung elasticity
What is the functional significance of the morphological and structural changes that happens to the lungs due to normal aging?
- impaired gas exchange
- air trapping
- ↓inspiratory /↓expiratory reserve volumes
- ↑resistance to airflow in small airways
- ↓pulmonary artery pressure
- ↓pulmonary capillary network
- ↓mucous clearance
What are the morphological and structural changes that happens to the other cardiopulmonary organs due to normal aging?
- ↓autonomic control
- ↓muscular ATP reserves
- ↓immune function
- ↓protective reflexes (i.e., gag & cough)