week 2 genetics Flashcards
sister chromatids
identical copies of chromatids formed by DNA replication of a chromosome, with both copies joined by a common centromere
homologous chromosome
set one maternal and one paternal chromosome that pairs up inside a cell during cell division
centromere
essential for cell divisions of cell
ensures accurate segregation of chromosomes
the most constricted part of a chromosome
holds two chromatids together
telomere
a region of the repetitive nucleotide sequence at the end of a chromosome that protects it from deterioration or fusion of neighboring chromosomes
how are chromosomes classified
according to their position of the centromere
telocentric
centromere found at the end of a chromosome which means there is no p arm , it does not exist in humans
acrocentric
centromere severely offset the center leading up to a much shorter p arm
submetacentric
the centromere is off-center leading to a shorter p arm relative to q arm
metacentric
the centromere is at the middle which means p and q arm are of comparable length
karyotype
an individual s collection of chromosomes
it is the number and appearance of chromosomes in the nucleus of a eukaryotic cell
involves isolation, staining, and visual examination
karyotype technique
- culture
- harvest
- analyze
karyotype- culture
- sample collection
- culture in growth medium
- incubate for 3 days