WEEK 2: Chapter 3 Flashcards
Axon to dendrite
Axodendritic
Axon to cell body
Axosomatic
Axoaconic
Axon to axon
Axon to muscle
Neuromuscular junction
Electric current flows along specialized proteins
Electrical
Both chemical and electrical transmission
Mixed
Neurotransmitters are manufactured in ______________
Presynaptic cells
Receptors for the chemical are located on the ___________ and _____________.
Postsynaptic cell, mediate the response of that cell
Neurotransmitters encompass several different kinds of Chemical Substances
1) Amino acids and monoamines
2) Acetylcholine (ACh)
3) ATP and adenosine
4) Neuropeptides, lipids, and gases
Synthesized by a different mechanism than other transmitters. Synthesized from precursor proteins that are synthesized in the cell body and shipped to the axon terminals.
Neuropeptides
Alter the action of standard neurotransmitters. Chemicals that do not act like typical neurotransmitters.
Neuromodulators
Ca2+ mediates release of transmitter from vesicles
Exocytosis
Transmitters are released only at ___________.
Active Zones
Vesicles are recycled by ____________.
Endocytosis
Three models of Vesicle recycling
1) Clathrin-mediated endocytosis
2) Ultrafast endocytosis
3) Kiss-and-run
Recycles large amounts of vesicle membrane during high rates of neuronal activity
Bulk Endocytosis
________ and _________________ Transmitters that are not released from synaptic vesicles
Lipid and Gaseous
Regulate the firing patterns of dopamine neurons and control the timing and amount of dopamine released from their terminals in target regions.
Autoreceptor
Inhibit further transmitter release
Terminal autoreceptors
Receive transmitters at axoaxonic synapses; either enhance or reduce transmitter release.
Heteroreceptors