WEEK 1: Chapter 2 Flashcards
Transmit information in the form of electric signaling
Neurons
Provide metabolic support, protection, and insulation
Glial cells
Convert physical stimuli into electrical signals
Sensory neuron
Direct bio-behavioral responses appropriate for the situation
Motor neuron
In brain and spinal cord; form interacting neural circuits; responsible for conscious sensations, recognition, memory, decision-making, cognition.
Interneurons
Cell body
Soma
Receive information from other cells across the synapse between
Dendrites
Conducts signal from cell body to terminal
Axon
Each neuron receives/integrates information from many cells
Convergence
Information may be transmitted from one neuron to a few or thousands of other neurons
Divergence
______ and ______ are constantly modified and can change in size, shape and in response to changes in synaptic transmission.
Dendrites and Spines
Terminal buttons have ____________ containing _______________ chemicals
Synaptic vesicles and Neurotransmitter
Are breaks in the myelin sheath, where action potentials are regenerated.
Nodes of Ranvier
Most axons are wrapped with _________, a fatty insulating coating created by layers of glial cells
Myelin Sheath
___________: Proteins that promote or obstruct formation of mRNAs by binding to the ______________ of the gene, modifying its rate of transcription
Transcription factors: promoter region
Production of complementary mRNA from DNA; takes place in nucleus
Transcription
_____________: Building protein molecules by linking amino acids specified by mRNA; takes place on ___________ in the cytoplasm
Translation and Ribosomes
Control of gene expression by chromosome modifications that don’t affect the DNA code
Epigenetics
Form myelin sheaths in the PNS, wrap one axon, promote regeneration of damaged axons
Schwann cells
Form myelin sheaths in the CNS; wrap many axons
Oligodendroglia
Structural support for neurons; modulate the extracellular environment; take up excess neurotransmitters
Astrocytes
Remove dying cells by phagocytosis at sites of nerve damage; source of immune response in the CSN
Microglia
Proteins made in the soma must be transported to the axon terminals
Axoplasmic transport
Depends on structures in the ____________–microtubules and neurofilaments that provide the cell shape
Cytoskeleton
Form a track for protein transport to the axon terminals, and back
Microtubules
Motor protein activated. Packet with newly synthesized protein
Anterograde
Motor protein activated. Organelle carrying waste materials
Retrograde
Proteins in the cell membrane include: _________, ___________, _____________, and _______________
Receptors, enzymes, ion channels, and transporters
Opens when a ligand binds to a receptor
Ligand-gated channel
Opens when electrical potential across the membrane is altered
Voltage-gated channel
_____________: inside of cell is more negative than outside: -70 millivolts (mV); it is _________.
Resting membrane potential and polarized
Elements that are more concentrated outside the cell
Na+ and Cl-
Helps maintain the ion distribution.
Na+-K+ pump
Rapid change in membrane potential that is propagated down the length of the axon
Action potential
Are Small, Transient Changes in Membrane Potential
Local Potentials
A stimulus opens Na+ channels to allow a few ions into cell; inside of cell becomes slightly more positive (excitatory)
Depolarization