Week 2

Question 1

Sterility depends on:

Answer 1

Environmental quality
Proper hand washing
Proper hand hygiene
Use of personal protective equipment
Primary and secondary engineering controls
Maintenance of equipment and environment
Aseptic technique

Question 2

Hand washing is

Answer 2

essential and critical step in preventing contamination

Question 3

Transient hand flora + Hand Washing

Answer 3

15% of all flora

Removed with hand washing

Question 4

Resident hand flora + Hand Washing

Answer 4

85% of all flora

Not removed by hand washing

Question 5

Spores + Hand Washing

Answer 5

Requires physical removal with hand washing

Not removed with hand sanitizers or alcohol

Question 6

Personal Protective Equipment (PPE)

Answer 6

Shoe Covers
Beard Covers
Hair covers
Jacket/gown
Gloves (sterile, powder-free)

Question 7

Donning PPE is used to:

Answer 7

Protect preparation from the operator

Protect the operator from the preparation

Question 8

Wash hands prior to donning gloves:

Answer 8

Hands can contaminate gloves when donned

Hands can transport particles onto gloves when donned

Question 9

When do you disinfect your gloves

Answer 9

Immediately after being donned
Prior to and after cleaning
Priot to each preparation
Prior to re-entering ISO Class 5 environment
If suspected to be contaminated
Periodically during prolonged duration of compounding in the PEC

Question 10

Critical sites are at

Answer 10

great risk of contamination via touch, moisture, contact with unclean air

Question 11

Needle Critical sites

Answer 11

Hub, tip and shaft of the needel

Question 12

Syringe Critical Site

Answer 12

Tip and ribs of the plunger

Question 13

Vial and Ampules Critical Site

Answer 13

Rubber closure when penetrated and opening of an ampule

Question 14

Steps of Aseptic Technique

Answer 14

Gather supplies
Disinfect
Prepare syringes and needle
Enter vial
Withdraw contents
Inject into diluent/solution
Mix and check final admixture
Cover and label

Question 15

Check against light and contrasting background for:

Answer 15

Incompatibilities
Particulate matter
Coring

Question 16

When is a priming infusion set necessary?

Answer 16

When the administration set needs to be attached to admixture prior to leaving the compounding facility

Question 17

When do you prime?

Answer 17

Before drug is added to bag

Question 18

Define Positive Pressure

Answer 18

If air added exceeds volume of solution withdrawn

Spraying or dripping of solution

Question 19

Define Negative Pressure

Answer 19

If air removed exceeds volume of solution removed

Difficulty removing volume needed from vial

Question 20

Define Batch Compounding

Answer 20

Involves the compound of multiple preparation containing the same ingredients
Requires specific documentation