Week 2 Flashcards

1
Q

What are the CNS, PNS, and Nerves

A

Central Nervous System- contains the brain and spinal cord
Peripheral Nervous System- contains the nerves and most sensory organs
Nerves- Bundles of individual neurons contained within a protective membrane

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2
Q

what are the three types of neurons

A

sensory neurons; a neuron that detect changes in the external or internal environment and sends information about these changes to the CNS.
Motor neurons; a neuron that controls the contraction of a muscle or the secretion of a gland.
Interneurons; a neuron located entirely within the CNS and have a communicative role

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3
Q

List the 4 key parts of a Neuron

A

1, Soma
2, Dendrites
3, Axon
4, Terminal Buttons

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4
Q

Explain the Soma

A

The Soma is the brain of the cell. It contains membrane cytoplasm nucleus and mitochondria

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5
Q

explain membrane cytoplasm nucleus and mitochondria

A

membrane is a double layer of lipid molecules within protein molecules in bedded that is substance detectors, security guards and transport is.
Cytoplasm fills the space surrounded by the membrane and contains organelles
nucleus contains the chromosomes – jeans – protein production – important for structure and function
Mitochondria is the energy extraction and ATP

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6
Q

explain dendrites and the synapse

A

Dendrites help individual neurons talk with one another

Synapse is neural messages that are transmitted from neuron to neuron across the small gap

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7
Q

Explain the Axon and the myelin sheath

A

an axon is a long tube that carries information from the Soma of a neuron to its terminal buttons called the action potential. The myelin sheath is a fatty substance that works as an insulator of the action potential

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8
Q

Describe axoplasmic transport, anterograde transport, retrograde transport, and microtubules

A

Axoplasmic transport: Active processes by which substances are propelled along the inside of the length of an axon.

anterograde transport: movement from cell body to terminal buttons

Retrograde transport: movement from the terminal buttons to the cell body

Microtubules: bundles of protein filaments arranged in a hollow core the act as a train tracks to propel substances along the axon. Also provide structural support to a neuron

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9
Q

What are terminal buttons

A

Located at the end of an axon

They secrete a chemical into the synapse = neurotransmitter

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10
Q

List the 4 types of Glial Cells + brief explanation

A

Astrocytes (CNS): provide nutrients to neurons
Oligodendrocytes (CNS): provide support to axons and produce the myelin sheath
Microglia (CNS): a very small glial cells involved in phagocytosis
Schwann Cells (PNS): similar to oligedendrocytes, produce a myelin sheath covering pns

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11
Q

Explain the Blood Brain Barrier

A

The blood brain barrier is a barrier that exists between the blood and the fluid that surrounds the cells of the brain that is selectively permeable. BBB is thinner in some areas (area postrema - vomiting)

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12
Q

what are inhibitory synapses and inhibitory into neurons responsible for

A

they are the reason why you do not drop a coffee cup when it is too hot for your hand. You are able to stop the motor neuron action and reflex of dropping the cup

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13
Q

What is an action potential

A

The communication of information within a neuron

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14
Q

what is an membrane potential

A

The electrical charge across the cell membrane is called the membrane potential. It is the difference in electrical potential inside versus outside of the neuron

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15
Q

What is a resting potential

A

axons at rest have a negative electrical charge called the resting potential (inside of the axon is more negatively charged compare to the outside)

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16
Q

Explain hyper polarisation and depolarisation

A

hyper polarisation is when the electrical charge of an axon goes from resting potential – more negative

depolarisation is when the electrical charge of an axon goes from resting potential – more positive

17
Q

when is In action potential more likely to be sent

A

when the neuron is D polarised it is more likely to send an action potential. Hyper polarisation is less likely to send an action potential

18
Q

how is membrane potential established

A

The electrical charge within the neuron is the result of to opposing forces, diffusion and electrostatic pressure

19
Q

Explain diffusion and Electro static pressure

A

diffusion is the movement of molecules from regions of high concentration to regions of low concentration.

Electrostatic pressure is the attractive force between atomic particles charged with opposite signs, or repulsive force between atomic particles charge with the same sign

20
Q

what are ions, cations, anions

A

ions are charged particles

cations are positive

anions are negative

21
Q

what are the ions related to membrane potential

A

organic ions which are negatively charged and remain inside the cell

chloride ions which are negatively charged and are mostly outside the cell

potassium ions which are positively charged inside the cell

sodium ions which are positively charged outside the cell

22
Q

what is the sodium potassium pump

A

The sodium potassium pump contributes to the negative membrane potential by constantly pushing sodium ions outside of the cell and pushing potassium ions in.
Specifically three sodium ions are pumped out and 2 potassium ions are pumped in.

23
Q

what are ion channels

A

Ion channels are protein molecules in the neuron membrane to open and close to allow ions to rush in and out of a neuron

24
Q

what is action potential propagation

A

the all or none law and the rate law (rate law means the principle that variations in the intensity of a stimulus or other info being transmitted in an axon are represented by variations in the rate at which an axon fires; how often an action potential is triggered)

25
Q

What are the two types of postsynaptic receptors

A

Ionotropic receptors - directly open with NT binding

Metabotropic receptors - indirectly opens ion channels

26
Q

what are the two mechanisms which end postsynaptic potentials

A

Reuptake: neurotransmitter removed from the Psynapse via special transport of molecules that work like a vacuum sucking the neurotransmitter back up directly into the cytoplasm of the presynaptic cell.

Enzymatic deactivation: destruction of a neurotransmitter by an enzyme after it has been released

27
Q

What are auto receptors

A

auto receptors are receptor molecules located on a neuron that respond to the neurotransmitter released by the neuron. They play a regulatory role in the release of neurotransmitters

28
Q

what are axoaxonic synapses 

A

Synapses found in the axon that influence the overall amount of neurotransmitter being released into the axodendritic synapse

29
Q

What are neuromodulators

A

They are a naturally secreted substance that acts like a neurotransmitter, except that it is not restricted to the synaptic cleft. They modulate activity of neurons in particular brain areas and are involved with vigilance

30
Q

What are hormones

A

they are a chemical substance released by Endo Crine glands. Cells with hormone receptors are called target cells.