Week 2 Flashcards

1
Q

COPD signs and symptoms

A

Cardinal symptoms of COPD include dyspnea, chronic cough, and or sputum production

Other signs and symptoms include decreased activity tolerance, wheezing, recurrent lower respiratory infections, chest tightness, fatigue, weight loss, anorexia, increased anterior posterior diameter of the thorax, use of accessory muscles for aspirations, prolonged expiration, hyperresonance on percussion, decrease heart/breath sounds, tachypnea, neck pain dissension during expiration and absence of heart failure, cyanotic skin color and clubbing of nail beds

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2
Q

COPD

A

Obstructive disease not fully reversible due to airflow limitations and hyper reactivity of airways, hyperinflation of lungs

Exacerbations and comorbidities determine the severity

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3
Q

COPD risk factors

A

Smoking, aging high and 65 to 75 year old, recurrent infections, repeated chemical/gases/irritants exposures, long-term asthma, alpha-1 antitrypsin defficiency

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4
Q

COPD diagnostic criteria

A

Gold standard is spirometry testing. Should be done and symptomatic patients only.

FEV1/FVC less than 0.70 & FEV1 less than 80%

Chest x-ray is not used to diagnose COPD however can rule out other diagnoses such as CHF, pneumonia, cardiomegaly, and pulmonary fibrosis

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5
Q

Spirometry testing for COPD

A

Symptoms for considering a diagnosis and performing spirometry including dyspnea, cough, chronic sputum production, recurrent lower respiratory tract infections, history of risk factors including family history of COPD and or childhood factors

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6
Q

COPD stage of severity

Stage 1: mild COPD

A

FEV1 greater or equal to 80% predicted

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7
Q

COPD stage of severity

Stage 2: moderate COPD

A

FEV1 less than 50% to less than 80% predicted

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8
Q

COPD stage of severity

Stage 3: severe COPD

A

FEV1 greater than 30% to less than 50% predicted

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9
Q

COPD stage of severity

Stage 4: very severe COPD

A

FEV1 less than 30% predicted

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10
Q

Management of COPD

A

Smoking cessation, flu vaccination annually, pneumonia vaccination at the age of 65 and older, reduce risk factor exposures, person centered and shared decision-making management plan, pulmonary rehab, oxygen use

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11
Q

COPD medication goals

A

Reduce symptoms, reduce exacerbations risk in severity, and prove exercising overall health

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12
Q

COPD radiographic findings

A

Chest x-ray alone is not diagnostic of COPD but can provide value in excluding differential diagnosis such as pulmonary disease, pneumonia, cardiomegaly.
Abnormalities associated with COPD may be present on a chest x-ray findings such as hyper inflation of the long, hyperlucency of the long, or tapering of vascular markings. Structural long disease may be seen on the chest imaging which is consistent with COPD.

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13
Q

COPD lab test

A

CBC with differential to rule out anemia, polycythemia which occurs in advanced COPD with hypoxemia, detecting the presence of infection with the white blood cell count, or if eosinophilia is present, considering an allergic/asthmatic component

Serum alpha-1 anti-trips in levels are recommended for individuals presenting with COPD at early ages less than 45 years in age and in non-tobacco users with emphysema or family history of COPD

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14
Q

COPD EKG changes

A

And COPD patients atrial arrhythmias are common. Peaked P waves and leads II, III, and AVF are often apparent in patients with pulmonary disease. An EKG in advance COPD may demonstrate evidence of a right axis deviation, sinus tachycardia, and pulmonary hypertension with the presence of ongoing as waves in the lateral precordial leads.

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15
Q

COPD exacerbations medication management

A

Usually occurs after URI‘s

Mild: Saba only
Moderate: Saba and oral corticosteroids
Severe: ER/hospital for acute respiratory failure
COPD action plan imperative to reduce rest of future exacerbation

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16
Q

COPD pharmacological treatment

SABA

A

Bronchodilation, relaxes smooth muscles in airway. Rapid onset. Rescue medication

Examples include albuterol, levoalbuterol, pirbuterol every 4-6 hours

17
Q

COPD pharmacological treatment

LABA

A

Bronchodilation, relaxes smooth respiratory muscles. Onset 10 to 20 minutes

Examples include salmeterol, formoterol every 12 hours

Daily LABAs include indacaterol and olodaterol

18
Q

COPD pharmacological treatment

Inhaled anti-cholinergics antimuscarinic
SAMA

Used in acute and maintenance

A

Blocks bronchoconstriction of acetylcholine

Caution and gloves, patience, BPH, bladder neck obstruction, allergy to atropine.

Anticholinergic side effects include can’t see, I can’t pee, I can’t spit, I can’t shit

Examples include ipratropium every 6-8 hours

19
Q

COPD pharmacological treatments

Inhaled anti-cholinergics LAMA
Maintenance treatment

A

Prevents bronchoconstriction, causes some bronchodilation

Caution and glaucoma patients, BPH, bladder neck obstruction, allergy to atropine

Examples include Tiotropium (Spiriva) and Umeclidinium (Ellipta) every 24 hours

20
Q

COPD pharmacological treatment

Combo LABA with ICS

A

FEV1 less than 60%. Best and combo with bronchodilators

Play improved bronchodilation reducing inflammation

Examples include Budesonide/formoterol (Symbicort), fluconazole/salmeterol (Advair), Vilabterol/flucanazole (Breo Ellipta)

21
Q

COPD pharmacological treatment

Systemic steroids

A

Short term used for a cute exacerbations

Anti-inflammatory actions

Examples include prednisone

22
Q

COPD pharmacological treatments

Methylxanthines

A

Risk for toxicity, drug interactions, toxic ADR

Oral bronchodilator

Examples include Theophylline