Week 14- Designer Drugs Flashcards
Designer drugs are often developed as
Derivatives of other drugs of abuse or medications
How to buy designer drugs
Street or internet
Are designer drugs safe?
Said to be- but they are lethal and often not detected on drug screens
Another name for MDMA and what does it do
Ecstasy and Molly
Inscreases serotonin (fever, seizure, coma, death)
Ghbs primary mechanism of action
Activation of gaba receptor
Rapid - cause disinhibition- amnesia- sexual arousal
What receptor does phenibut act on
GABA
How can dextromethorphan be obtained and what does it cause
Over the counter
Hallucinations, mood liability, dissociation
What do ketamine and pcp act as
Glutamate antagonists
They are dissociatives and cause paranoia
Cathinones are
Stimulants derived from khat plant
What has stimulant properties at low doses and mu opioid agonist activity at high doses
Kratom
What drives the increase in fatal opioid overdoses
Heroine and high potency full synthetic opioids (fentynyl, carfentanil)
Hallucinogens that activate serotonin
Lsd and c2 analogue
How does campral work
Balances gaba and glutamate
Helps abstinence
How does antibuse work?
Alters metabolism of alcohol making ingestion of alcohol unpleasant
Methadone, Suboxone, vivitrol
Methadone- full agonist
Sub- partial agonist
Viv- antagonist
Stabilize brain chemistry, block euphoric effects, relieve physical cravings and normalize body functions
