Week 12 Opioids Flashcards

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1
Q

Leading cause of accidental death

A

Opioid drug overdose

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2
Q

Any substance that activates the mu- opioid receptor

A

Opioid

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3
Q

Opioids can be 3 things

A

Syntethic
Semi senthetic
Naturally occurring

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4
Q

What 3 characteristics make heroine highly addictive

A

Short half life
Rapid
Potent

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5
Q

Is opioid withdrawal fatal?

A

No

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6
Q

How can opioid withdrawal be fatal

A

Poorly treated withdrawal can result with patients leaving treatment and dying

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7
Q

Opioid intoxication

A

A cute - pinpoint pupils, dry mouth, intensity (lower dose) nodding out (high dose) , pale skin, depressed respiration’s, euphoria

Long term- weight loss, malnutrition, poor hygiene, constipation, urinary hesitantancy, scarring

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8
Q

Opioid withdrawal

A

7-14 days
Protracted 6 months or longer
Tachycardia, sweats, dysphoria, insomnia, pain, dialated pupils, runny nose, agitation, nausea, tremors, yawning, goose flesh skin, drug craving

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9
Q

Suboxone has both

A

Naloxone - opioid antagonist

Buprenorphrine- opioid partial agonist

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10
Q

Difference between buprenophrine and methodone

A

Buprenorphrine- opioid partial agonist

Methadone- opioid full agonist

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11
Q

What two things is tramadol

A

Weak mu-receptor agonist

Has snri properties

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12
Q

How many half lives does it take to clear a substance from the body

A

Takes 5 half lives to get to steady state and to clear out of system

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