Week 13: Ocular Adnexa and Lacrimal System Flashcards
List the muscles of the forehead
- Frontalis
- Orbicularis oculi
- Corrugator
- Procerus
Describe the innervation of the muscles of the forehead and muscles surrounding the orbit
- Innervated by the frontal branch of CNVII (facial nerve)
- Frontalis
- Originates on scalp and inserts into superior orbital rim
- Raises the brows, forehead wrinkles, moves scalp posteriorly - Orbicularis Oculi
- Sphincter muscle arranged in concentric bands around the upper & lower lids
- Function: close lids and lowers the entire brow.
- Assists in tear drainage. - Corrugator
- Originates on the frontal bone & inserts into the medial side of brow
- Creating vertical furrows between brows - Procerus
- Originates on nasal bone & inserts into medial side of frontalis.
- Creating horizontal furrows over the bridge of the nose
List functions of the eyelids
- Cover the globe for protection
- Deliver oxygen supply during sleep
- Spreads tear film over the surface of the eye
- Move the tears toward drainage at the medial canthus on eye lid closure
Describe the eyelid
- Primary protectors of the tear film, corneal nerves, and conjunctiva
- Proper lid closure, innervation & blink mechanisms are designed to produce, mix, and spread the tear components across the ocular surface
- Guides movement of tear film and debris through the nasolacrimal apparatus
- When the lids fail to do their job, a host of problems will occur (e.g. dry eye/inflammation)
Describe the eyelid margin structure
- Rests against the globe, contains eyelashes and pores of the meibomian glands
- Orifices of meibomian gland located posterior to cilia
- Gray line: divides the lids into anterior and posterior portions, runs between cilia & meibomian gland pores
Two zones divided by the punctum:
- Lacrimal portion
- Ciliary portion
Describe what is in the ciliary portion
- It contains pores of meibomian glands and cilia (eyelashes)
What are the functions of the ciliary portion/eyelashes?
- Protect the eye via stimulation causing blink reflex
- Protect from airborne particles
- Prevent transfer of pathogens and allergens to the eye
- Involved in non-verbal communication
Describe the blink reflex
- Passes through trigeminal afferent (V1 stimulating eyelashes; cornea)
- Brainstem
- Facial efferent to orbicularis oculi
List the nerves and branches of the ophthalmic division of CNV and what the branches innervate
- Frontal (largest branch)
- Supraorbital: innervates upper eyelid, conjunctiva, scalp
- Supratrochlear: innervates upper eyelid, conjunctiva, forehead - Lacrimal (smallest branch)
- Receives branch from zygomatic nerve of CNV2 containing parasympathetic fibres
- Innervates upper eyelid, conjunctiva, lacrimal gland
- Contains parasympathetic & sympathetic efferent to lacrimal gland - Nasociliary
- Anterior ethmoid nerve: innervates mucous membranes of frontal, ethmoid sphenoid sinuses
- Posterior ethmoid nerve (~ 30% of people): innervates mucous membrane if sphenoid sinuses
- Infratrochlear nerve: innervates upper eyelid, conjunctiva, bridge of nose
- Long ciliary nerves (contains sympathetic fibres to dilator pupillae muscle: innervates eye
List the structures of the eyelid
- Orbicularis oculi muscle
- Palpebral portion
- Orbital portion - Superior palpebral levator muscle
Describe Orbicularis Oculi Muscle and its portions
- Innervated by frontal branch of CNVII
- Palpebral portion
- Consists of semi circle muscle fibres and occupies area resting on globe
- Contraction helps drain the tears through the canaliculi into the nasolacrimal duct
- Contraction of pretarsal orbicularis closes the lids & involved in involuntary blink - Orbital Portion
- Upper fibres of this portion blend with the frontalis and corrugator
- Contraction closes the eye tightly & muscles on face, forehead
Describe Superior Palpebral Levator Muscle
- Function: contraction of levator causes elevation of the eyelid
- Innervated by CNIII (oculomotor nerve)
- Originates from the sphenoid bone above the globe
Describe the conjunctiva and list them with a short description
- Consists of a surface epithelium overlying a well vascularized stroma
1. Limbal conjunctiva: where conjunctiva & cornea meet at the limbus
2. Bulbar conjunctiva: covers the anterior sclera
3. Palpebral conjunctiva: lines posterior surface of both eyelids
4. Fornix conjunctiva: folded conjunctiva where palpebral and bulbar conjunctiva meet
List the type of glands and function for:
- Meibomian
- Glands of moll
- Glands of zeiss
- Accessory lacrimal gland
- Meibomian
- Sebaceous
- Secretion. of meibum: lipid which is responsible for outer layer of tear film - Glands of moll
- Modified apocrine
- Secretion of antimicrobial peptides and proteins for protection of lashes and ocular surface - Glands of zeiss
- Sebaceous
- Release sebum to hydrate cilia - Accessory lacrimal gland
- Merocrine
- Secretion of antibacterial agents, lysozyme, lactoferrin, immunoglobulins
List the measurements of the tear film and the layers with its thickness
- Tear Film = 7 µm thick
- pH tear film = 7.6
- Composed of 3 layers:
1. Outer Lipid Layer/oily layer (0.1 µm thick)
2. Intermediate Aqueous Layer/watery layer (7 µm thick)
3. Inner Mucous Layer/mucous layer (0.5 µm thick)
What are the functions of tear films
- Optical: uniform interface between air and cornea
- Mechanical: remove intrinsic and extrinsic debris from tear film
- Lubricant: allows for smooth movement of lids over globe
- Waste removal: removes by products of metabolism from cornea
Explain the tear supply process
- Receives Parasympathetic input
- Consists of small clusters of secretory cells forming small lobules
- Lumen combine to form large ducts that open into the upper lateral fornix
- Tear fluid is produced at a rate of 1 µL/min = 1.5 mL/day
- Infants younger than 6 weeks do not produce tears
Describe the Lacrimal Gland Innervation (afferent and efferent)
Afferent:
- Sensory nerves on cornea (nasocillary nerve CNV1)
- Arrives at trigeminal nucleus
Efferent :
- Parasympathetic innervation of lacrimal gland
- Sympathetic innervation of lacrimal gland originate from Superior Cervical Ganglion
- Central Nervous System –> Facial nerve exits the pons –> Zygomatic branches of the maxillary nerve travel with the lacrimal nerve —> lacrimal gland
- Increases tear secretion
Describe the tear drainage during blink
- Tears move freely into puncta
- Puncta close at the start of blink due to orbicularis muscle and puncta contact
- Further compression of orbicularis compresses canaliculi & lacrimal sac moving fluid to nasolacrimal duct
- After blink lacrimal sac and canaliculi expand and pressure decreases drawing fluid in from open puncta
Describe evaporated dry eyes
- Tear Film instability
- Hyperosmolarity
- Neurosensory abnormalities
- Inflammation and damage
Describe Aqueous Deficient Dry Eye
- Low volume of tears
- Hyperosmolar tears
- Ocular surface inflammation – initiates a vicious cycle
Give examples of Dry Eye Management for:
- Dietary Modifications
- Local Environment Conditions
- Complementary Medicines
- Lid Margin and Tears
- Anti-Inflammatory Therapy
- Surgical Therapies
- Dietary Modifications = water hydration, essential fatty acids (omega 3)
- Local Environment Conditions = chronic topical medications
- Complementary Medicines = honey
- Lid Margin and Tears = topical antibiotics, IPL therapy
- Anti-Inflammatory Therapy = steroid therapy
- Surgical Therapies = lid corrections