Week 13 Antidepressants

Question 1

All antidepressants hold a Black Box Warning risk of suicidal thoughts and behaviors. Under which circumstances does this risk increase most?

Answer 1

During the first 2 months of treatment and when the patient is less than 24 years of age

Question 2

Which statement describes the mechanism of action among tricyclic antidepressants (TCAs) versus a newer antidepressant, such as escitalopram (Lexapro)?

Answer 2

TCAs are less selective.

TCAs have many sites of action. They bind to histamine, dopamine, serotonin, and norepinephrine, which makes them nonselective.

Question 3

An 8-year-old has been diagnosed with major depression. Which medication is preferred for this patient?

Answer 3

Fluoxetine is an approved serotonin reuptake inhibitor for children in treating major depression.