WEEK 13 ANEMIA PART 1 Flashcards

1
Q

decrease in the O2 capacity of blood

A

Functional

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2
Q

reduction from the baseline value for the total number of RBCs, circulating Hb and RBC mass (Hct

A

Operational

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3
Q

below the previously established reference value of healthy individuals of the same age, gender, race and environment

A

Conventional

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4
Q

most common symptoms of anemia

A
  • shortness of breath
  • fatigue
  • weakness
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5
Q

Example of lab procedures for detecting anemia

A
  • CBC
  • Iron studies
  • Hb electrophoresis
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6
Q

Unhealthy diet causes a reduction of how much volume of iron

A

1 mg per day

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7
Q

Decrease of oxyhemoglobin on skin

A

pallor

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8
Q

Skin indication of start of hemolysis

A

jaundice

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9
Q

Breakage of capillaries

A

Petechiae

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10
Q

in physical examination, what is the indicator of patient having a severe case of anemia

A

Eyes (hemorrhage)

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11
Q

general causes of anemia

A

Decreased RBC prod
Increased RBC destruction
Blood loss

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12
Q

Anemia that is the most common and easiest to treat

A

Iron Deficiency Anemia

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13
Q

Blockage in the heme synthesis

A

Sideroblastic anemia

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14
Q

Deficiency of Vitamin B12 and Folate

A

Megaloblastic Anemia

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15
Q

anemia associated with decreased production of WBC, RBC and platelets. Associated with the Bone Marrow

A

Aplastic Anemia

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16
Q

Hallmark of aplastic anemia

A

pancytopenia

17
Q

What are the diseases under
Anemia due to endocrine disorders

A

Cushing syndrome
Addison’s disease

18
Q

Associated anemia due to marrow infiltration

A

Myelophthisic anemia

19
Q

What are the main causes of Increased destruction of RBC

A

Intracorpuscular Abnormality (intrinsic)
Extracorpuscular Abnormality (extrinsic)

20
Q

Intracorpuscular Abnormality (4)

A
  • membrane defect
  • enzyme deficiency
  • paroxysmal nocturnal hemoglobinuria
  • globin abnormality
21
Q

Diseases associated under Mechanical in Extracorpuscular Abnormality

A

MAHA (HELLP)
Hemolysis elevated liver low platelet count
- thrombotic thrombocytopenic purpura
- hemolytic uremic syndrome
Traumatic cardiac hemolytic anemia

22
Q

HELLP is commonly seen in

A

pregnant patients

23
Q

What are the diseases associated in Infection under Extracorpuscular abnormality

A

Hemolytic anemia
- malaria
- babesia
- bartonella