HEMA LEC WEEK 14 Flashcards

1
Q

High WBC count

A

leukocytosis

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2
Q

what is the absolute leukocyte count of leukocytosis

A

11.0x10^9/L

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3
Q

what is the absolute leukocyte count of leukopenia

A

<3.0x10^9/L

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4
Q

other quantitative disorders with absolute leukocyte count of <3.0

A

neutropenia
granulocytopenia
lymphopenia
pancytopenia

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5
Q

what is the absolute neutrophil count of neutrophilia

A

> 7.0-8.0

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6
Q

pathologic causes of neutrophilia

A
  • infection
  • malignancy
  • inflammation
  • metabolic disorders
  • drugs
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7
Q

specific fungal that causes neutrophilia

A

actinomycosis

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8
Q

specific viral that causes neutrophilia

A

varicella
variola
rabies
herpes zoster

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9
Q

malignancy

A

neoplastic growth

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10
Q

abnormal growth of tissue

A

neoplastic growth

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11
Q

examples of inflammation that causes neutrophilia

A

serosal
visceral
blood cell destruction
post traumatic
thermal injury
chemicals or drugs

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12
Q

what are the common metabolic disorders that causes neutrophilia

A

diabetes
renal dysfunction
liver disease

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13
Q

common drugs that causes neutrophilia

A

corticosteroids
lithium

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14
Q

examples of physical stimuli that causes neutrophilia

A

exercise
excessive temp changes
nausea
vomiting
pregnancy
labor

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15
Q

emotional stimuli that causes neutrophilia

A

rage
panic
stress

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16
Q

most common type of leukopenis

A

neutropenia

17
Q

what is the absolute neutrophil count of neutropenia

A

<1.76 - 1.8

18
Q

extreme neutropenia

A

agranulocytosis

19
Q

absolute neutrophil count od agranulocytosis

A

<0.5

20
Q

what are the causes of neutropenia

A

decreased neutrophil prod
inherited stem cell disorders
acquired stem cell disorders
increased neutrophil destruction
infections
immune reactions
drug induces
increased sequestration
pseudoneutropenia

21
Q

what is an example of inherited stem cell disorder that causes neutropenia

A

fanconi syndrome

22
Q

what are the common examples of acquired stem cell disorders that causes neutropenia

A

chemical toxicity
marrow replacemsnt
nutritional deficiencies
cytotoxic drugs

23
Q

example of bacterial infections that causes neutropenia

A

bacterial
- typhoid
- paratyphoid
- brucellosis

24
Q

examples of viral infections that causes neutropenis

A

measles
yellow fever
hepatitis
mononucleosis
rubella

25
Q

immune reactions that causes neutropenia

A

neonatal isoimmune neutropenia (maternal IgG)
autoimmue

26
Q

common examples of immune reaction that causes neutropenia

A

lupus
felty’s syndrome

27
Q

common examples of drug induced that causes neutropenia

A

amidopyrine
cephalosphorins

28
Q

associated with splenic enlargement and increased margination

A

increased sequestration

29
Q
A