Week 12 GI Flashcards
What are the main components of the GI tract?
Oral cavity
Esophagus
Stomach
Small & large intestines
What are the 4 basic histological layers of the GI tract?
Mucosa
Submucosa
Muscularis externa
Serosa/Adventitia
Describe the gingiva
Gingiva = gums
Lightly keratinized stratified squamous epithelium
Richly vascularized lamina propria
What is the most common dental pathology in children and adults?
Gingivitis
Bacterial invasion results in accumulation of plasma cells/B cells in the lamina propria and destruction of collagen.
Describe oral mucosa
Stratified squamous epithelium
Basement membrane
Lamina propria
3 types:
Lining (lips, cheeks, soft palate)
Masticatory (gingiva, hard palate)
Specialized (dorsum of tongue)
What are the major salivary glands?
Parotid
Sublingual
Submandibular
Structure and function of salivary glands
Salivary glands are made up of serous and mucous cells surrounded by myoepithelial cells.
Striated ducts modify secretions by resorbing Na creating a hypotonic secretion.
What types of secretions come from the:
1. Parotid gland
2. Submandibular gland
3. Sublingual gland
- Totally serous
- Mostly serous
- Mostly mucous
What do glands secrete?
Amylase
Mucous
Bacterial lysozyme
Immunoglobulins
What is the 25 rule?
The GI tract is about 25 ft long
The esophagus is about 25 cm long
Discuss the structure of the esophagus
Mucosa
Submucosa
Muscularis externa
Adventitia
Mucosa: strat squam nonkeratinized epithelium, with underlying lamina propria and muscularis mucosae.
Small mucous glands release thin highly viscous mucous film to lubricate luminal surface.
Multilayer epithelium protects against abrasion. Renews 14-21 days.
Discuss the difference between the upper esophagus, middle esophagus, and lower esophagus
Upper: 2 layers of skeletal muscle
Middle: mixed skeletal and smooth muscle
Lower: 2 layers of smooth muscle
What delineates the esophagogastric junction?
Zigzag (Z) line: juncture of esophageal and gastric mucosa.
SSNKE transitions to simple columnar epithelium.
What are the anatomic regions of the stomach?
Cardia
Fundus
Body
Pylorus
What are the 4 layers of the stomach wall?
Mucosa
Submucosa
Muscularis externa
Serosa
What are the main cells types of the stomach?
Surface mucous cells
Mucus neck cells
Parietal cells
Chief cells
Enteroendocrine cells