Week 11 - SCL Care Flashcards
Why do we bother with lens hygiene?
• reduce the number of microorganisms that accumulate on the lenses with wear
• minimise the risk of infection with contact lenses
• cleaning solutions can also improve comfort by conditioning and wetting the lens surface
What challenges do CL solutions face before being approved for use?
• Tested for ability to protect vs organisms:
- Pseudomonas (lens associated keratitis)
- Serratia (nun-ulcerising keratitis and endopthalmitis)
- Staphylococcus (microbrial keratitis - 25%)
- Candida (yeast infections)
- Fusarium (common fungus in 1st world)
What other challenges do CL solutions face?
• MRSA (methicillin-resistant Staphylcoccus aureus) - CL solutions have varying degrees of efficacy
• Acanthomoeba (amoeba) - found in tap water, very stubborn to kill in their cyst form. CL solutions have varying degrees of efficacy. Good compliance helps!
What 5 things must all solutions have in common?
• Sterile, stable at room temperature
• Harmless (relatively) to eye if accidentally instilled
• Have no adverse effects on contact lens materials
• Compatible with any other solutions
• Self-sterilising
What 3 steps are there to cleaning SCLs?
- Cleaning
- Rinsing
- Disinfecting / Storage
What is cleaning specifically?
• To clean debris from the lens
• To reduce deposit build up
• Important to include a lens “rub” step in cleaning regime to mechanically remove debris and deposits (oils, proteins,
“biofilm”)
What are the lenses cleaned with?
• Surfactant (surface-acting agent): poloxamer
• Hydrophilic and hydrophobic ends in molecule
• Hydrophobic interacts with debris to form micelles, hydrophilic reacts with water
• Effective against lipids and inorganic deposits
• Enhances lens wettability
What is rinsing?
• To clear the debris away that has been dislodged by the cleaning
• Prior to disinfection
• This can be done with MPS (multi-purpose solution) or sterile saline
Why is Disinfecting taken place, how is it done?
• Neutralise all microbes present on CL
• Different disinfectants take different lengths of time: check label
• Typically done overnight (once a week for EW)
• Refers to keeping solution in bottle safe, not just lenses
What are the 3 terms associated with antimicrobials, and their definitions?
- Sterilisation: the solution is sterile: BUT the solution does not sterilise lenses.
- Preservation: the preservatives present in the solution that prevent growth of micro-organisms in the bottle.
- Disinfection: the reduction of the level of micro-organisms to a level that is safe for the ocular surface without damaging the contact lens. This occurs in the contact lens case.
What are some examples if Biocides used in CL solutions?
• PHMB
• PAMB
• PQ-1
• MAPD
What are Multi-purpose solutions (MPS)
• The most convenient and common design
• Used for cleaning, rinsing and disinfecting
• Research showed apart for some fungal isolates, MPSs performed adequately (99.9% viability reduction) on FDA test-panel organisms
• Most CL companies have MPS options
- So do some of high street companies
MPS Steps - Bausch and Lomb example…
• Place 3 drops of MPS each side of lens, rub for 20s
• Rinse each side 5s with MPS
• Place cleaned lens in case, fill with fresh fluid at least 4hrs - discard solution from case after each use
What is the Hydrogen Peroxide CL system?
• Very different from MPS
• Hydrogen peroxide has broad antimicrobial activity - 3% concentration
• Destroys pathogens by oxidation, by denaturing protein; damaging membranes
• Preservative free!
• Requires catalyst to neutralise hydrogen peroxide, turning to water
• Disinfection takes 6hrs overnight
What are the 7 steps for REMOVING lenses with hydrogen peroxide?
- BEFORE handling your contact lenses wash, rinse, and dry hands
- Remove R lens and place into R basket, Carefully close the basket. Repeat for left eye.
- Rinse each eye in lens holder for 5s with peroxide
- Fill lens case up with peroxide solution
- Place lens holder in case, close cap securely. Solution will bubble.
- Allow 6hrs to soak, do not shake/turn upside down the case