Week 11 Developmental Disabilities and Pediatric/Adolescent Mental Health Flashcards

1
Q

adolescent depression is higher:

A
  • females
    • by age 14, it is 2x in girl
  • having depressed parents have 3x the risk
    • peak 15-20 yrs
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

what framework gathers info about young person’s life and aids in gathering history:

A
  • HEADSS
    • Home
    • Education, employment, eating, exercise
    • Activities and peer relationships, social media
    • Drug use, prescribed meds, cigarettes, vaping, alcohol and other drugs
    • Sexuality and gender
    • suicide, self harm, safety, and spirituality
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

when to start MDD screening in adolescents? what tools?

A
  • ALL adolescents beginning age 12-18
  • pediatric symptoms checklist (PSC) - 4 yrs to 18 yrs
  • Beck Depression inventory - adolescents
  • PHQ-2 (if > 3, do PHQ-9) - 6 yrs and up
  • CDRS-R
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

depression in adolescents vs adult

A
  • adolescents: don’t admit to “feeling sad” but have mood swings, irritability, short tempered, temper tantrum, social w/drawal, somatic complaints
  • toddlers: lack energy, too eager to please others, clingy
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

depression diagnosis criteria

A
  • _>_5 symptoms below AND depressed mood or anhedonia x 2 weeks:
  • SIGECAPS:
    • Sleep changes/insomnia
    • Interest (loss) - anhedonia, hopelessness
    • guilt, worthlessness
    • energy loss, fatigue
    • concentration/cognition (decreased)
      • school/hw
    • appetite (changes)
      • increase/weight gain
    • psychomotor (agitation/retardation)
    • suicide
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Management for adolescents with depression

A
  • Cognitive behavioral therapy
  • mild: CBT. if no response in 6-8 weeks, meds!
  • complex: CBT + SSRI (1st line) [or SNRI/citalopram]
    • fluoxetine (Prozac) for > 8 yrs
    • escitalopram (Lexapro) > 12 yrs citalopram (Celexa) and sertraline (Zoloft)
    • always CBT with meds (never alone)
  • always assess suicide risk
  • r/o underlying causes (CBC, TSH, CMP, B12, Folate)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

avoid what medication as treatment for adolescent depression?

A
  • paroxetine (Paxil)
    • a/s with increased suicide ideation
  • TCA’s (-tyline/nortripyline) = no benefit either
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

follow up interval for SSRI in adolescent

A
  • EVERY week x 4 weeks, then every other for at least 2 visits
  • again 12 wks later
  • Once remission of sx’s, f/u every 3 months
    • continue meds for 6-12 months after remission WITH CBT
  • always screen for SI/recurrent depression & document
  • if stop meds, taper slowly over 1-2 months
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

why follow up so quickly for adolescents on SSRI’s?

A
  • slight increase in suicidal ideation when starting SSRI educate to look out for it
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

if SSRI not helping adolescent depression and you maxed out the dose…

A
  • switch to another SSRI!
  • if 2nd SSRI no work → refer to psychiatrist (they will switch to another class, venlafaxine or bupropion)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

General screening q’s for youths about nutrition and body dissatisfaction

ask this T/F question for diabetic youths

A
  • how do you feel about your weight?
  • how much do you like to weigh?
  • do you, ur friends, or ur fam have any concerns about your eating, exercise, or weight?
  • “I sometimes take LESS INSULIN than I should”
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

purging behavior (bulimia) can lead to

A
  • loss of gastric acid
  • hypokalemic hypochloremic
  • metabolic alkalosis
  • laxative abuse → hypokalemia
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

DSM 5 diagnosis of ADHD

A
  • < 17 yrs old:
    • need 6 or more hyperactivity/impulsivity sx’s
    • OR 6 or more of inattention sx’s
  • > 17 yrs old, need 5 or more
  • sx must:
    • occur often, in 2 or more settings for at least > 6 months
    • present before 12 months, impair work, school, home, severe
  • inattention sx’s:
    • fails to pay attention/careless mistakes
    • difficulty paying attention
    • doesn’t listen
    • avoids tasks that require sustained mental effort
    • loses things to complete tasks
    • easily distracted
    • often forgetful in daily activities
  • hyperactivity/impulsivity sx’s:
    • fidgets /squirms
    • leaves seat when needed to be seated
    • runs/climbs when inappropriate
    • trouble playing quietly
    • always on “go”
    • talks excessively
    • answers q’s before q is completed
    • difficulty waiting for his or her turn
    • interrups/intrudes others
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

ADHD scales/screening

A
  • Vanderbilt ADHD
  • ADHD rating scale IV
  • Connor Parent & Teacher rating scale
  • Child attention profile
  • CDC checklist
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

types of ADHD

A
  • primary inattentive (6 or more positive behaviors in inattentiveness category)
  • primary hyperactive/impulsive (^)
  • combined type (6 or more positive in each category)

ADD term no longer used

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

ADHD treatment plan

A
  • identify comorbid conditions & treat
    • hearing/vision screening
    • tutoring
  • behavior management plan
    • identify specific goals (2-3 behaviors)
    • reward system for meeting goals
    • online resources AAP, CDC< CHADD
  • medication - stimulants + CBT
    • NO meds for preschoolers unless severe/refractory to CBT
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

challenges in diagnosing and treating ADHD in adults

A
  • comorbidities (anxiety, depression, drug use)
    • refer mental health
  • childhood symptom recall (sx’ before age 7?)
    • mostly primary inattentive bc not disruptive
  • behavior scales
    • ASRS scale with 18 behaviors, need to be in 2 settings
    • tx difficult bc CVD, abuse,
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

meds for ADHD

A

SNRI - Atomoxetine (Strattera) non stimulant

methylphenidate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Down syndrome features

A
  • most common: hypotonia (poor muscle tone) & short stature
  • microcephaly
  • flattened midface
  • brachycephaly (flattened occiput), round face
  • up slanting palpebral fissures “almond eyes”
  • epicentral folds (vertical folds of skin b/t medial acanthi and bridge)
  • brush field spots
  • protruding tongue
  • macroglossia
  • short neck, skin folds
  • broad shortened hands
  • clinodactyly of little finger
  • transverse palmar crease
  • sandal toe deformity (inc spacing b/t 1st and 2nd toe)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

Causes and variations of Down syndrome

A
  • nondisjunction of 21st chromosome [most common]
  • translocation
  • mosaicism
  • increasing in rates and affects all racial/socio levels
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

Down syndrome evaluation before discharge

A
  • ECHO! (50% have congenital heart defects) even with no murmur
  • TSH
  • hearing screening
  • CBC (hem abnormalities, myeloproliferative disorder, leukemia reaction, polycythemia)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

Down syndrome screening

A
  • ECHO
  • CBC

screen for:

  • congenital heart disease
  • childhood leukemia
  • thyroid disease (hypo/hyper)
  • autoimmune dz (celiac, diabetes, dermatological)
  • seizure disorders
  • decrease hearing/vision
  • autism; behavior problems
  • Atlantoaxial subluxation
  • sleep apnea (eval by age 4)
  • other:
    • otitis media
    • bronchitis
    • GI illnesses
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

what tendencies do Down syndrome have that’s normal?

A
  • the “Groove” / OCD tendencies
  • self talk / imaginary friends (esp when stressed)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

neuropsychiatric disorders in down syndrome and what to exclude?

A
  • depression
  • Alzheimer disease (1 gene of Alz on 21st chromosome)
  • anxiety disorders
  • compulsive disorders
  • autism
  • ADHD
  • exclude treatable medical conditions:
    • obstructive sleep apnea
    • hypothyroidism
    • celiac sprue
    • atlantoaxial subluxation → behavioral changes
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
Q

screenings for adults with down syndrome

A

Screen TSH annually/yearly!

  • testicular, ovarian, cervical, breast (routine), colon, leukemia (but would have found as child)
  • celiac screen in children, not adults
  • echo if haven’t already
  • ophthalmologic and hearing q 2 years
  • sleep study for OSA using polysomnography by age 4 (not routine)
  • karyotype is used for diagnosis
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
26
Q

PE of Down syndrome that warrant special attention

A
  • obesity
  • HEENT: cerumen impact, hearing impairment, chronic sinusitis, allergies, reflux, cataracts, keratoconus, vision impair, airway compromise
  • thyromegaly, thyroid nodules, atlantoaxial subluxation
  • pneumonia
  • murmur, cardiomegaly, cyanosis
  • testicular masses, cryptochordism, Pap screen
  • arthritic changes, hallux valgus (bony deformity on 1st MTP)
  • cervical cord compression, nerve root compression, vertebrobasilar insufficiency, motor weakness, ankle conus
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
27
Q

dysthymic disorder criteria

A
  • category of depression
  • depressed mood for most days for at least 2 years
  • must not have gone more than 2 months w/o 2 or more of:
    • poor appetite or over eating
    • insomnia
    • low energy
    • low self esteem
    • poor concentration
    • difficulty making decisions
    • feelings of hopelessness
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
28
Q

most important risk factor for suicide

A

previous attempt!

29
Q

warning signs of adolescent suicide

A
  • obsession/poems essay on death
  • dramatic change in appearance
  • threats
  • guilt/shame/reflection
  • making amends
  • changes in eating/sleeping
  • giving away personal items
  • drop in grades
30
Q

hospitalize adolescent for SI if

A
  • plans to access lethal means
  • hx of prior attempts
  • impaired judgment
  • question of safety at home
31
Q

management on generalized anxiety

A
  • excessive anxiety/worry NOT focused on specific person/situation/stressor
  • toddler/preschool: CBT and play therapy
  • older child: ped mental health therapy + CBT
    • consider SSRI
    • NO BENZOs
32
Q

first line treatment for mild to moderate OCD in adolescents

A

CBT

if severe: SSRI

33
Q

what psych disorder has the highest risk of suicide?

A

bipolar disorder

90% recurrent after 1st manic. episode

34
Q

bipolar disorder treatment

A
  • SAFETY!
  • refer to child behaviors health provider
  • lithium (mood stabilizers) alone or with anti seizure meds (valproate, divaproex) or with antipsychotics (risperidone)
  • non pharm:
    • healthy diet
    • stress reduction
    • routine exercise
    • good sleep hygiene
35
Q

what meds can worsen manic response and cause metabolic disorders?

A

antidepressants can potential manic

36
Q

what is the most common mental health problem in childhood?

A

ADHD

more in males

37
Q

ADHD med management (stimulant vs non stimulant)

A
  • stimulant:
    • low dose amphetamine (Adderall)
    • methylphenidate: Concerta, Ritalin
    • Amphetamines: adderall, Vyvanse
      • more potent than methylphenidate
  • non stimulant:
    • atomoxetine (Strattera) SNRI for > 6 yrs old
      • increase SI risk
    • guanifacine + clonidine > 6 yrs old
      • takes 1-2 wks for effect
38
Q

autism stats/patho

A

5x more common in boys, all racial groups

  • MUST have sx at young age and can’t be late onset
  • fragile X most common cause
39
Q

autism screening gold standard

A
  • 18 and 24 months during wellness checks
  • EARLY INTERVENTION!
    • prognosis better if diagnosed < 5 years
  • Autism Diagnostic Observation Schedule (ADOS-2) and Autism Diagnostic Interview (ADI-R) gold standard
    • M-CHAT screen at 16-30 (toddler) quick, easy
  • screen autistic sibling
    • if + = refer
      • if < 3 yrs: refer for early intervention
      • if > 3 yrs: refer for special education
    • if - & parents concerned, rescreen next visit
  • citalopram contraindicated
40
Q

autism behaviors to look for/red flags for early dx

A
  • lack of social smile and eye contact by 2-3 months
  • lack of joint attention 9 months
  • doesn’t point at objects to show interest by 14 mo
  • no babbling/cooing by 12 mo
    • doesn’t say a single word by 16 mo
  • no pretend by 18 mo
  • loss of language/social skills by 2 yrs
  • does not respond to name by 1 yr
  • gets upset by minor changes
  • avoids eye contact / wants to be alone
  • repeats words/phrases
  • monotone
  • flaps hands, rocks body, spins circles
  • self injury behaviors (head banging, biting, pinching)
41
Q

autism diagnosis criteria

A
  • deficits in ALL 3:
    • social-emotional reciprocity: reduced sharing of interest
    • nonverbal communicative - poor eye contact
    • developing, maintaining and understanding relationships
  • 2 or more of:
    • repetitive movements, use of objects, speech (echolalia)
    • insistence on sameness, routines, ritualized patterns
    • highly restrictive interest
    • hyper or hyperactivity to sensory or input
  • must impair function, present in early development
42
Q

anorexia / bulimia questionnaire

A

SCOFF

  • do you make yourself Sick bc u feel uncomfortably full?
  • control - do you worry u lost control over what you eat?
  • loss more than One stone in 3 months period
  • do you think you’re fat when ppl think you’re thin?
  • would u say food dominates your life?
43
Q

anorexia diagnostics

A
  • R/o pregnancy → get UA
    • bone density studies with amenorrhea (osteopenia)
  • CBC (anemia), electrolytes, fasting glucose (new onset diabetes), thyroid studies (hyperthyroid), LFTs, FSH, LH
    • hypokalemia, hypochloremia (purging)
  • EKG (PVC’s and QT elongations)
44
Q

anorexia management

A
  • refer behaviors health + dietician + rehab + therapy
  • meds that decreases binging/purging:
    • antidepressants
      • fluoxetine (PRozac) -
      • TCAs [NO in SI pts]
    • atypical antipsychotics
      • topiramate (Topamax)
      • olanzapine (Zyprexa) - stimulate appetite/weight gain instead of decreasing binging
  • Expected weight gain 1.1 lb per week from referring
    • monitor for refeeding syndrome: confusion, irritability, organ dysfunction, seizure)
45
Q

how is Fragile X inherited

A
  • X linked dominant inheritance (FMR1 gene mutation)
    • females have XX
      • milder sx’s bc have 2 X’s to compensate
    • males have XY
      • more sx’s
  • 2nd common after Down syndrome
  • women: 50% passing chance (carrier or syndromic)
  • carrier men:
    • pass premutation to ALL daughters (carriers only), none to sons
46
Q

fragile X screening in who?

A
  • pts with autism
  • children with intellectual disability (idiopathic)
  • children with family hx of
47
Q

Fragile X clinical findings

A
  • (think elephant)
  • prominent forehead & jaw
  • long ears
  • long narrow face
  • epicanthal folds
  • high arched palate
  • increased head circumference
  • large testes (macroorchidism)
  • club foot/ples planus, hip dislocation, scoliosis
  • OSA
  • follow age appropriate health promo per AAP Bright futures
48
Q

Turner syndrome

A
  • ONLY females
  • Missing X / altered chromosome from error in division
  • UNLIKELY TO BE INHERITED
49
Q

Turner syndrome sx’s

A
  • most common: short stature
  • loss of ovarian function/immature ovaries/infertility
  • no puberty
  • heart defects
  • webbing of neck (NB)
  • lymphedema of hands/feet
  • MOST INFERTILE
  • normal IQ
50
Q

turner syndrome management

A
  • refer to endocrinology for tx → start Growth Hormone before 4 yrs old for puberty to hit 12-14 yrs
  • low dose estrogen first then add progesterone 1-2 years after
51
Q

Klinefelter syndrome

A
  • extra X chromosome (XXY) → getting more feminine features
  • MALES ONLY
  • NOT an inherited disorder; it’s an error in cell division
52
Q

klinefelter syndrome sx’s

A
  • tall with long arms
  • reduced facial/body hair
  • gynecomastia/boobies
  • small testes
  • less facial hair
  • narrow shoulders, wider hips
  • osteoporosis/weak bones
  • infertility
  • metabolic syndrome
  • cryptocordism / undescended tests
  • normal IQ but language/learning problem
53
Q

klinefelter syndrome screening

A
  • if infancy had hypotonia, delayed milestones, screen!
  • or all, abdominal fat, clumsy, slow dev skills from 1-5 yrs old
54
Q

klinefelter syndrome management

A
  • testosterone RT at puberty age
    • stimulates deeper voice, hair, muscle, libido
  • improves bone density
    • DOES NOT IMPROVE FERTILITY
    • most men unable to father a child without help of fertility specialist
  • fertility treatment: intracytoplasmic sperm injection right into egg
  • monitor scoliosis
  • annual thyroid screen
  • increased risk of autoimmune and malignancies (breast cancer)
55
Q

Marfan’s syndrome features

A
  • cardiac - monitor ~
    • aortic root dilation
    • Mitral valve prolapse, regurgitation
  • tall, long limbs
  • pectus deformities (pigeon)
  • joint hyperextensibilities
  • eyes: ectopic lentis, myopia, retinal detachment, esotropia/strabismus
  • spontaneous pneumothorax
  • normal IQ
56
Q

marfans syndrome management

A
  • avoid contact sports
  • annual eye exam
  • monitor cardiac
57
Q

watch out for evidence of what in patients with anxiety?

A

physical trauma

58
Q

separation anxiety disorder

A
  • 5-16 yrs old
  • most common pediatric anxiety disorder
  • meds are NOT helpful
  • manage with psycho/education
59
Q

generalized anxiety disorder management in preschoolers

A

**preschoolers benefit from play therapy

60
Q

peds depression diagnostics/labs

A
  • CBC
  • EBV titers
  • Vit D
  • TSH
  • HCG
  • UA
  • drug screening with NEW onset of depression
61
Q

what can occur 4-6 weeks after a stressful infection?

A
  • PANDAS - pediatric autoimmune neuropsychiatric disorder associated with streptococcus infection
  • in peds with OCD and Tourettes
  • give PO corticosteroids or IVIG
62
Q

bipolar diagnostics/labs

A
  • urine/saliva/serum sample for toxicology screening if no known previous diagnosis
  • CBC
  • CMP
  • TSH
  • renal profile
63
Q

before giving a stimulant for ADHD…

A

screen for cardiovascular risk (family history, obese, DM, dyslipidemia, hx of stroke/MI/TIA)

64
Q

Prader Willi Syndrome treatment

A
  • loss of function on chromosome 15 → constantly hungry (hyperphagia) at 12-24 months
  • hypogonadism → infertile
  • give sex hormone, growth hormone
65
Q

Beckwith Wiedemann Syndrome

A
  • overgrowth syndrome affecting infants
  • macrosomia
  • parts of body growth big and uneven
  • omphalocele
  • macroglossia
  • risk for wills tumor, hypoglycemia
66
Q

what is the expected weight gain per week after refeeding of anorexia?

A

1.1 lb (0.5kg) per week

monitor for refeeding syndrome (confusion, irritability, organ dysfunction, seizure) from severe fluid and e- imbalance

67
Q

bulimia treatment

A
  • my role: screening & early identification
  • referral for children/adolescents bc of sociopyschological dynamics
  • nutritional rehab
  • cognitive behavioral psychotherapy
  • antidepressant (SSRI)
  • PE: parotid glands, mouth, dental caries, esophageal or gastric injury, dehydration (from laxatives), ipecac a/s hypotension, tachycardia, arrhythmias
  • check e-, Mg, amylase levels
68
Q

diagnostics for eating disorders

A
  • CBC (anemia)
  • e- (K, Na, acid-base imbalance)
  • fasting glucose (diabetes)
  • TSH (hyperthyroidism)
  • LFT
  • FSH
  • LH
  • ECG (premature ventricular contractions and QT elongation)
  • bone density
69
Q

which medications cause metabolic disorders (Diabetes, dyslipidemia)

A

atypical antipsychotics