Final: IE, Murmurs Flashcards
infectious endocarditis
- microbial infection w/in endothelium of heart veg
- vegetation forms on endothelial structures
- 50% are > 50 yrs old (2men:1women)
- acute: death days-6wks: staph aureus
- subacute: death 6 wks-3 months: & chronic: death > 3 months
- viridan’s streptococci
*risk factors of infectious endocarditis
- IV drug use
- structural cardiac abnormalities
- implantable devices
- cardiac/vascular prostheses
- immunosuppression
- IE hx
IE clinical presentation
- fever
- (absent in elderly, immune comp, CHF, renal failure, tx’ed with previous antibiotics)
- chills, weight loss
- conduction disturbances, heart block, pericarditis, fistulas, fibrosis leaflets
- murmurs
- CHF (poor prognosis)
- emboli
- neurologic or opthalmologic → Roth spots
- PE - IVDU or indwelling central line
- splenic septic emboli
- petechiae
- janeway lesions - macules palms, soles from septic embolization
- osler nodes - painful nodules finger, toe pads
- renal failure
- arthralgias/myalgias
- proximal joints/lower extremities, monocular unilateral
infectious endocarditis diagnostics
- gold standard to dx: THREE sets of blood cultures (from 3 diff sites before antib started)
- 2nd set 1 hr after 1st
- CBC
- CRP/ESR
- EKG
- continuous monitoring for perivalvular abscess
- TransthoracicEcho (TTE)
- TransesophagealEcho (TEE)
- cardiac CT if echo not clear
Infectious endocarditis management/treatment
- transfer to ED if have fever and sus IE! consult specialist
- infectious dz consult: IV antibiotics (IV!! only)
- improve in 1 week - recheck cx’s (should be - )
- if fungal org → antifungals + valve replacement surgery
**infectious endocarditis prophylaxis for dental, oral, respiratory procedures and WHAT ANTIB?
- antibiotics prior to procedure (dental or other surgical procedures)
- cardiac transplant and valvulopathy
- Prosthetic valve
- prosthetic material in valve repair w/in first 6 months of surgery
- hx of infectious endocarditis
-
amoxicillin oral 2g once 30-60 mins before procedure
- or clindamycin oral 600 mg if PCN allergy
if suspect IE…
refer to ED!!! ideally with cardiac surgery availability
where is aortic area?
Right upper sternal border or 2nd ICS
**where is pulmonic area?
Left upper sternal border or 2nd intercostal space
where is the tricuspid area?
left lower sternal border
where is the mitral area?
apex
Grade III murmur
moderately loud
Grade IV murmur
loud, palpable thrill
grade V murmur
very loud with thrill, heard when stethoscope partly off chest
early systolic murmur
- least common
- high pitched, sharp
- pathologic
- mitral or tricuspid regurgitation
*midsystolic murmur
- most common
- crescendo-decrescendo that build in intensity as velocity increases then decreases well before S2
- heard in aortic or PS
- valsalva maneuver increases murmur in hypertrophic cardiomyopathy
late systolic murmur
- start mid or late systole
- continue to s2 in crescendo pattern
- in MVP or tricuspid valve prolapse
pansystolic
- result from blood flow transferring from high pressure chamber to low pressure
- mitral regurgitation or tricuspid valve or VSD
what does diastolic murmurs indicate
pathologic and heart disease bc of regurgitation or stenosis
*Stills murmur
- benign innocent murmur
- classic vibratory/musical parasternal precordial murmur
- mid systolic
- mid left sternal border and apex
- common in healthy infants, children 3-6 yrs or 8-12 yrs
- asymptomatic, no abnormal findings
****when to refer with murmurs?
pathologic murmurs:
- diastolic, holosystolic murmur
- grade 3 and up systolic murmurs
- murmur with extra heart sounds (S3, S4, or click)
- murmur that increases in intensity when pt stands
murmur diagnostics
- EKG
- chest xray
- ECHO
- stress test if asx severe VHD
Stages of valvular heart disease
- Stage A: has risk factors
- Stage B: with progressive VHD (mild-mod, asx)
- Stage C: Asx with severe VHD
- C1 - asx w/ severe VHD with L or R ventricle compensating
- C2 - asx w/ severe VHD with decompensation of L or R ventricle
- Stage D: have sx’s
*valvular heart disease complications
- heart failure
- volume overload → leads to changes in heart muscle wall
- reduced functional status
- L ventricular pump failure
- Death - from dysrhythmias
NP role in VHD
- history - know risk factors in PMH
- PE - recognize early heart sound changes
- aus / inspect chest wall, palp pulse, PMI
- diagnosis - if SOB, fatigue, edema, new murmur
- get diagnostics and refer
- refer to Level 2 primary valve center - surgery (w/w/o CABG) or Level 1 for transcatheter valve replacement
- get diagnostics and refer
Systolic murmurs
MR. Peyton Manning AS MVP
- Mitral regurgitation
- physiological murmur
- aortic stenosis
- mitral valve prolapse
diastolic murmurs
ARMS
- aortic regurgitation
- Mitral Stenosis