week 10: karyotyping and genotyping

Question 1

karyotyping/genotyping is a collection of..

Answer 1

k - chromosomes
g - genes

Question 2

karyotyping/genotyping identifies…

Answer 2

k - changes in shape, size, number of chromosomes
g- allele/variants present in particular gene

Question 3

karyotyping/genotyping determines..

Answer 3

k - ploidy level (no of copies)
g - zygosity (homo or hetero)

Question 4

karyotyping/genotyping can be used to..

Answer 4

k - check for abnormalities (eg checking unborn baby)
g - identify pathogens, GMO presence, drug response etc.

Question 5

how does karyotyping/genotyping work?

Answer 5

k - metaphase chromosomes (FISH), interphase chromosomes (aCGH)
g - SNV detection through PCR Taqman, Sanger..
OR
Repear sequence detection (tells one person from another)