week 10- cancer Flashcards
what are the stages of the cell cycle where things can go wrong
Gene expression
Cell signaling
The cytoskeleton and the cell cycle
Studying the cell cycle, cell survival, and cell death
what is a tumour
Abnormal and excessive growth of cells
what is the pathological features of cancer
Unrestrained proliferation is just one feature.
types of Tumors
Carcinomas: Arise from epithelial cells.
Sarcomas: Arise from connective tissues.
Both can be deadly if malignant.
Tumor Classification
Benign tumors grow slowly, don’t invade other tissues.
Malignant tumors spread rapidly, invade nearby tissues.
a -sarcoma’
is a connective tissue cancer
‘-carcinoma’
epitheal cell cancer
‘-oma
tumouos growth
Adeno
cellular arrangement seen in glands.
what are the 2 factors of cancer
genetic and environment
how is cancer caused
faulty genes
what are the effects of the faulty genes
then that is a loss-of-function mutation
gain-of-function
what is an example of a loss of function gene
loss of a protein that is required for a cell cycle checkpoint to operate normally.
what is an example of a gain in function gene
it may cause inappropriate production of an enzyme, or activate a regulated pathway when there is no signal for it.