Week 10 - Birth Flashcards

1
Q

When does the uterus first become palpable?

A

At around 12 weeks

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2
Q

When does the uterus reach the level of the umbilicus?

A

At about 20 weeks of gestaton

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3
Q

When does the uterus reach the level of the xiphisternum?

A

At about 36 weeks of gestation

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4
Q

What is classified as premature or pre-term labour?

A

Expulsion of the products of conception before 37 weeks of gestation

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5
Q

What is the girth at the umbilicus until 24 weeks gestation? How much does it increase until term?

A

Remains at about 60 cm average

Should increase by about 2.5 cm per week until term, when it should be 100 cm

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6
Q

What is the approximate diameter of presentation when the baby lies longitudinally in a cephalic presentation, well-flexed so that its vertex presents to the pelvic inlet?

A

9.5 cm

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7
Q

What diameter does the birth canal need to have approximately to allow the fetus to pass through?

A

10 cm

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8
Q

What is the true diameter of the pelvic inlet?

A

Normally about 11 cm

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9
Q

What changes must occur in the cervix to create a birth canal?

A

The cervix must dilate and be retracted anteriorly

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10
Q

What structural changes does cervical ripening involve?

A
  1. Marked reduction in collagen and marked increase in glycosaminoglycans which reduce the aggregation of collagen fibres
  2. Keratin sulphate increases at the expense of dermatan sulphate
  3. In consequence, collagen bundles loosen
  4. There is also influx of inflammatory cells and increase in nitric oxide output
  5. All of these changes are triggered by prostaglandins - namely E2 and F2x
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11
Q

Identify the oestrogen mediated changes in the cervix and pelvis occurring in advancing pregnancy that will facilitate birth.

A
  1. Cervical softening

2. Relaxation of pelvic ligaments

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12
Q

Where is the pelvic inlet shorter?

A

In the anterior-posterior plane (obstetric conjugate = 10.5 cm)

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13
Q

Where is the pelvic outlet narrowest?

A

Mediolaterally (11 cm)

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14
Q

What may failure of progression in labour occur because of?

A
  1. Inadequate power - insufficient uterine contractions
  2. Inadequate passage - abnormal bony pelvis, rigid perineum
  3. Abnormalities of the passenger - fetus too big, fetal presentation
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15
Q

What is progress in labour plotted graphically on?

A

A partogram

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16
Q

What is the mechanism of action for prostaglandins and oxytocin in inducing labour?

A
  1. Prostaglandins: enhance release of calcium from intracellular stores
  2. Oxytocin: lower the threshold for triggering action potentials
17
Q

What is a major producer of prostaglandins?

A

The endometrium

18
Q

What controls the synthesis of prostaglandins?

A

Prostaglandin release is controlled by the release of phospholipase from liposomes - the major factor influencing this in the endometrium is the oestrogen/progesterone ratio

19
Q

What increases prostaglandin synthesis?

A
  1. A rise in oestrogen and a fall in progesterone

2. The action of oxytocin